Results 101 to 110 of about 890,170 (340)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Optimal Sampling for Dynamic Complex Networks With Graph-Bandlimited Initialization

IEEE Access, 2019
Many engineering, social, and biological complex systems consist of dynamical elements connected via a large-scale network. Monitoring the network’s dynamics is essential for a variety of maintenance and scientific purposes.
Zhuangkun Wei, Bin Li, Weisi Guo
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Enhancement of Sparse Spasmodic Sampling using Novel Machine Learning Fusion Technique [PDF]

Iranian Journal of Electrical and Electronic Engineering
This research explores the demands of compressive sensing (CS) and Machine learning (ML) in biomedical signal processing. The sparse spasmodic sampling (SSS) technique has gained significant attention in compressive sensing.
Umesh Mahind, Deepak Karia, Vijay Kapure, Sankit Kassa   +3 more
doaj  

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

One-Bit LFM Pulse Radar: Harmonic Analysis and Target Reconstruction

IEEE Access, 2019
One-bit radar, adopting one-bit analog-to-digital converters to perform signal sampling and quantization, is a promising technology for low-cost and resource-limited applications.
Benzhou Jin, Xiaofei Zhang, Bo Zhao, Gang Wu   +3 more
doaj   +1 more source

Phase retrieval from low-rate samples [PDF]

, 2014
The paper considers the phase retrieval problem in N-dimensional complex vector spaces. It provides two sets of deterministic measurement vectors which guarantee signal recovery for all signals, excluding only a specific subspace and a union of subspaces,
Boche, Holger, Pohl, Volker, Yang, Fanny
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

A Hilbert Space Theory of Generalized Graph Signal Processing

, 2019
Graph signal processing (GSP) has become an important tool in many areas such as image processing, networking learning and analysis of social network data.
Ji, Feng, Tay, Wee Peng
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source