Results 161 to 170 of about 4,799,990 (289)

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

VISTA-SSM: Varying and irregular sampling time-series analysis via state-space models. [PDF]

Psychol Methods
Brindle B, Hull TD, Malgaroli M, Charon N.   +3 more
europepmc   +1 more source

The 28 + 28 day design is an effective sampling time for analyzing mutant frequencies in rapidly proliferating tissues of MutaMouse animals. [PDF]

Arch Toxicol, 2021
Marchetti F, Zhou G, LeBlanc D, White PA, Williams A, Yauk CL, Douglas GR.   +6 more
europepmc   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Determination of optimal sampling time of grape embryo rescue based on near infrared spectroscopy combined with machine learning. [PDF]

Plant Phenomics
Wang F, Bian L, Zhan Z, Chen Y, Ling C, Guo H, Gai Y, Liu G, Xu T, Wang Y, Xu Y, Huo Y.   +11 more
europepmc   +1 more source

Diagnostic performance of rapid antigen test for COVID-19 and the effect of viral load, sampling time, subject's clinical and laboratory parameters on test accuracy. [PDF]

J Infect Public Health, 2021
Amer RM, Samir M, Gaber OA, El-Deeb NA, Abdelmoaty AA, Ahmed AA, Samy W, Atta AH, Walaa M, Anis RH.   +9 more
europepmc   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Effects of the sampling time on the vaginal microbiota in healthy pregnant women: a prospective observational study. [PDF]

AJOG Glob Rep
Mori H, Shibata E, Kondo E, Saito M, Yoshino K, Fukuda K.   +5 more
europepmc   +1 more source

Accuracy of Broiler Activity Index as Affected by Sampling Time Interval. [PDF]

Animals (Basel), 2020
Yang X, Zhao Y, Tabler GT.
europepmc   +1 more source