Results 171 to 180 of about 139,353 (284)

An Evaluation of Pretrained Generative Models for Augmenting Small Health Data: Comparative Modeling Study. [PDF]

J Med Internet Res
Huet-Dastarac M, Dankar FK, Liu D, El Kababji S, Pilgram L, El Emam K.   +5 more
europepmc   +1 more source

Stochastic Beams and Where To Find Them: The Gumbel-Top-k Trick for Sampling Sequences Without Replacement

, 2019
The well-known Gumbel-Max trick for sampling from a categorical distribution can be extended to sample k elements without replacement. We show how to implicitly apply this ’Gumbel-Top-k’ trick on a factorized distribution over sequences, allowing to draw
Kool, W., Welling, M., van Hoof, H.
core  

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Effect of Care Bundle Approaches on External Ventricular Drainage-Related Infection: Systematic Literature Review and Meta-Analysis. [PDF]

Neurosurg Pract
Fariña Nuñez MT, Percuoco V, Parvin R, Barbagallo M, Voglis S, El-Hajj VG, Elmi-Terander A, Edström E, Thorne L, Serra C, Regli L, Staartjes VE, Vasella F.   +12 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Bayesian Dosing Simulator (BDS): A Pharmacokinetic Modeling Tool for Optimized Antibiotic Therapy. [PDF]

Pharmacotherapy
Valadez A, Scheetz MH, Neely MN, Donnelly HK, Korth E, Wunderink RG, Rhodes NJ.   +6 more
europepmc   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Fractionated testosterone gel replacement therapy in clinical practice: A real-world exploratory clinical experience. [PDF]

Endocrine
Maltese V, Delbarba A, Gatta E, Vetrugno S, Sansone A, Cappelli C.   +5 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source