Results 91 to 100 of about 7,676,917 (278)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Análisis de la Ley 26659 sobre condiciones para la exploración y explotación de hidrocarburos en la plataforma continental argentina

open access: yesRevista Jurídica Austral
La Ley 26659 sobre condiciones para la exploración y explotación de hidrocarburos en la plataforma continental argentina fue sancionada para proteger los recursos de petróleo y gas presentes en dicha zona y reafirmar la soberanía argentina sobre las ...
Carlos Sánchez Mas
doaj   +1 more source

PENERAPAN SAN REMO MANUAL PADA PENGIRIMAN (SATGAS MTF) TNI DALAM MISI UNIFIL

open access: yesArena Hukum, 2016
At the year of 2009 for the first time Indonesia took part by send a warships (KRI) for peacekeeping mission in UNIFIL (United Nations Mission Interim Forces in Lebanon).
Martha Latu Retno
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Boletín de literatura antigua cristiana

open access: yesEstudios Eclesiásticos, 1975
El presente estudio realiza un recorrido por diferentes autores pertenecientes a la literatura antigua cristiana. De forma concreta, aborda los escritos y fuentes como san Ireneo, el Evangelium Petri, Lactancio, san Atanasio, san Eusebio de Cesarea, san ...
José A. de Aldama
doaj  

Ciencias humanas, creencias y literatura

open access: yesAustral Comunicación
En este trabajo se estudia, desde conceptos de la teoría de redes, la creación y articulación de las redes intelectuales católicas en la Europa de entreguerras.
Enrique Sánchez-Costa
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Méthode sans questions, questions sans méthods

open access: yesVersants. Revista suiza de literaturas románicas, 2017
Dans tous ces cas, l’analyse littéraire joue le rôle d’un indispensable garde-fou épistémologique et on voit bien qu’elle est susceptible de s’appliquer à des corpus de discours qui ne sont pas proprement ‘littéraires’. Déléguer aux experts ‘non-littéraires’ la tâche que ces derniers doivent assumer, ce n’est pas seulement réduire la littérature à des ...
openaire   +3 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

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