Results 71 to 80 of about 1,869,450 (267)

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Effect of solution-blended poly(styrene-co-acrylonitrile) copolymer on crystallization of poly(vinylidene fluoride)

open access: yeseXPRESS Polymer Letters, 2010
Effect of solution-blended poly(styrene-co-acrylonitrile) (SAN) copolymer on crystallization of poly(vinylidene fluoride) (PVDF) was investigated by Fourier transform infrared spectroscopy (FTIR), differential scanning calorimetry (DSC) and wide angle X ...
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

Méthode sans questions, questions sans méthods

open access: yesVersants. Revista suiza de literaturas románicas, 2017
Dans tous ces cas, l’analyse littéraire joue le rôle d’un indispensable garde-fou épistémologique et on voit bien qu’elle est susceptible de s’appliquer à des corpus de discours qui ne sont pas proprement ‘littéraires’. Déléguer aux experts ‘non-littéraires’ la tâche que ces derniers doivent assumer, ce n’est pas seulement réduire la littérature à des ...
openaire   +3 more sources

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Boletín de literatura antigua cristiana

open access: yesEstudios Eclesiásticos, 1975
El presente estudio realiza un recorrido por diferentes autores pertenecientes a la literatura antigua cristiana. De forma concreta, aborda los escritos y fuentes como san Ireneo, el Evangelium Petri, Lactancio, san Atanasio, san Eusebio de Cesarea, san ...
José A. de Aldama
doaj  

Book Review: San Dictionary/San-woordeboek. San–Afrikaans–English/Eng-lish–San–Afrikaans/Afrikaans–San–English.

open access: yesLexikos, 2010
Ferdie Weich. San Dictionary/San-woordeboek. San–Afrikaans–English/Eng-lish–San–Afrikaans/Afrikaans–San–English. First edition/eerste uitgawe. 2004, xi + 377 pp. ISBN 0 7978 2704 8. Johannesburg: Macmillan South Africa Publishers (Pty) Ltd. Price/Prys: R198.
openaire   +3 more sources

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