Results 91 to 100 of about 3,325,360 (317)
Ninety-fourth annual Commencement of the University of San Francisco, Sunday, June 7, 1953
94th annual commencement held Sunday, June 7, 1953 at the War Memorial Opera House, San ...
University of San Francisco
core
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Effect of solution-blended poly(styrene-co-acrylonitrile) (SAN) copolymer on crystallization of poly(vinylidene fluoride) (PVDF) was investigated by Fourier transform infrared spectroscopy (FTIR), differential scanning calorimetry (DSC) and wide angle X ...
doaj +1 more source
Ninetieth annual Commencement of the University of San Francisco, Sunday, June 5, 1949
90th annual commencement held Sunday, June 5, 1949 at the War Memorial Opera House, San ...
University of San Francisco
core
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Eighty-third annual Commencement of the University of San Francisco, Sunday, May 31, 1942
83rd annual commencement, held Sunday May 31, 1942 at the War Memorial Opera House, San ...
University of San Francisco
core
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Yucca in residence garden, San Antonio, Texas, 1880s
Photograph shows a stereoscopic view of yucca ''Spanish daggers'' in the yard of an unidentified house. Note gingerbread design on house porch.Imprint on mount: ''San Antonio View Co.'
San Antonio View Company / Frank Hardesty (San Antonio, Tex.)
core
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Je rappelle ici l’une des plus constantes préoccupations de la pensée de Jean-Luc Nancy : celle du destin d’un Occident qui, au moment même où il paraît accomplir son élargissement au monde entier, est amené à faire, de plus en plus, le constat de son propre effacement, de son déclin, ou de sa finitude. Je le fais tout en déplaçant quelque peu le point
openaire +1 more source

