Results 101 to 110 of about 7,676,917 (278)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Erasto M. Villa: un diplomático argentino que prestigió su profesionalidad en Japón

open access: yesRevista Política Austral
Este artículo pretende destacar la profesionalidad y prestigio de los miembros del Servicio Exterior de la Nación de la República Argentina, especialmente la figura de quien fuera uno de sus miembros, el embajador Erasto M. Villa.
José Ramón Sanchis Muñoz
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Book Review: San Dictionary/San-woordeboek. San–Afrikaans–English/Eng-lish–San–Afrikaans/Afrikaans–San–English.

open access: yesLexikos, 2010
Ferdie Weich. San Dictionary/San-woordeboek. San–Afrikaans–English/Eng-lish–San–Afrikaans/Afrikaans–San–English. First edition/eerste uitgawe. 2004, xi + 377 pp. ISBN 0 7978 2704 8. Johannesburg: Macmillan South Africa Publishers (Pty) Ltd. Price/Prys: R198.
openaire   +3 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

VAI TRÒ VÀ TIỀM NĂNG CỦA NGÀNH THỦY SẢN ĐỐI VỚI SỰ PHÁT TRIỂN KINH TẾ CỦA ĐỒNG BẰNG SÔNG CỬU LONG, VIỆT NAM

open access: yesTạp chí Khoa học Đại học Cần Thơ, 2013
Vai trò và tiềm năng của thủy sản ở đồng bằng sông Cửu Long (ĐBSCL) đã được phân tích, đánh giá thông qua dữ liệu sẵn có. Kết quả thấy sản lượng khai thác cao nhất ở những tỉnh ven biển là Kiên Giang và Cà Mau, những tỉnh nội địa là An Giang và Đồng Tháp.
Trần Văn Việt
doaj  

Effect of solution-blended poly(styrene-co-acrylonitrile) copolymer on crystallization of poly(vinylidene fluoride)

open access: yeseXPRESS Polymer Letters, 2010
Effect of solution-blended poly(styrene-co-acrylonitrile) (SAN) copolymer on crystallization of poly(vinylidene fluoride) (PVDF) was investigated by Fourier transform infrared spectroscopy (FTIR), differential scanning calorimetry (DSC) and wide angle X ...
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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