Results 121 to 130 of about 129,549 (262)

Monogenic and syndromic obesity in children: Clinical recognition, genetics, and precision management

open access: yesPediatric Investigation, EarlyView.
Monogenic and syndromic obesity in children often arises from defects in the leptin–melanocortin pathway. Understanding these rare genetic causes not only clarifies mechanisms of appetite regulation but also enables precision therapies, offering hope beyond lifestyle interventions.
Hadel Khalil   +2 more
wiley   +1 more source

Proteomic Changes in Cancer Cell Lines as a Result of Bacterial Infection

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Bacterial infections have been implicated in shaping the tumor microenvironment (TME), but their effects on cancer cell proteomes remain unexplored. In this study, we analyzed proteomic changes in melanoma (A375) and ovarian cancer (OVCAR3) cell line models following infection with Staphylococcus aureus strain USA300 or Salmonella enterica ...
Bo Ren   +7 more
wiley   +1 more source

Open letter: The need for a site‐based biodiversity standard measuring and certifying impacts from nature‐based projects

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Despite growing investment in restoration, weak accountability and poor biodiversity monitoring mean many projects fail to achieve ecological recovery. The Global Biodiversity Standard (TGBS) offers a practical way to ensure that restoration finance delivers measurable gains for nature.
David Bartholomew   +254 more
wiley   +1 more source

Nutritional properties, traditional uses and potential new applications for the sotol plant (Asparagaceae, Convallarioideae): A review

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Sotol (Dasylirion spp.) is a resilient desert plant that sustains ecosystems, cultures and livelihoods in Chihuahua Desert. Our review highlights its nutritional properties, traditional uses and potential new applications in food, pharmaceuticals, renewable energy and water remediation. By synthesizing evidence across disciplines, we show how sotol can
Dámaris Leopoldina Ojeda Barrios   +7 more
wiley   +1 more source

Drought stress modulates indirect defense via bottom‐up effects in tomato and wheat

open access: yesPest Management Science, EarlyView.
Different water regimes can have a significant impact on plant morphology and defense pathways in tomato and wheat, triggering multiple olfactory choices in biocontrol agents of key insect pests. These findings could be used to implement biocontrol strategies within the IPM context under a changing climate scenario.
Mariangela Milordo   +8 more
wiley   +1 more source

Outcomes in Military Blood Donors at Joint Base San Antonio With Reactive <i>Trypanosoma cruzi</i> Antibody Screening Results. [PDF]

open access: yesOpen Forum Infect Dis
Wells MJ   +10 more
europepmc   +1 more source

The Allium cepa Derived Compound Propyl Propane Thiosulfonate (PTSO) Improves Tumorigenesis Due to Its Immunomodulatory Effect: A Preclinical Study

open access: yesPhytotherapy Research, EarlyView.
In vitro and in vivo effects of PTSO in colorectal cancer preclinical models, highlighting antiproliferative, pro‐apoptotic, barrier‐enhancing, antitumor, prebiotic and immunomodulatory properties. Created using BioRender. ABSTRACT Allium‐derived organosulfur compounds offer significant health benefits.
María Jesús Rodríguez‐Sojo   +16 more
wiley   +1 more source

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