Results 181 to 190 of about 4,129,026 (254)

Protein Corona Engineering of Lipid Nanoparticles Enables Efficient Functional Gene Silencing in the Liver

Small, EarlyView.
By shaping the protein corona, lipid composition directs LNP tropism and enables the preferential delivery of a TIMP1‐targeting siRNA to liver macrophages. In a murine model of primary biliary cholangitis, this strategy promoted macrophage reprogramming and attenuated liver fibrosis.
Naths G. Sukubo, Serena Renzi, Martina B. Violatto, Leila Altigieri, Anna L. Capriotti, Andrea Cerrato, Aldo Laganà, Luca Digiacomo, Erica Quagliarini, Antonio Minopoli, Massimiliano Papi, Daniela Pozzi, Carlo A. Scirè, Pietro Invernizzi, Paolo Bigini, Giulio Caracciolo   +15 more
wiley   +1 more source

“It's Not Equality, …It's Not Humanizing:” Content‐Area Teachers' Tensions Between CCR Curriculum and Linguistically Responsive Professional Development

TESOL Quarterly, EarlyView.
Abstract This qualitative study explores how secondary content‐area teachers of emergent bilingual (EB) students navigate tensions between linguistically responsive professional development (PD) and the implementation of state‐mandated College and Career Readiness (CCR) curricula in south Texas.
Caryn Calisi, Jerry Romero Jr., Bedrettin Yazan, Jorge Solís, Kristen Lindahl, Michael Cabantac Mauricio, María Leija, Gilberto Lara, Amanda de Oliveira Silva   +8 more
wiley   +1 more source

Investigating SME‐Inclusive Public‐Private AI Innovation Network: Evidence From U.S. Small Business Administration (1991–2023)

Thunderbird International Business Review, EarlyView.
ABSTRACT Understanding innovation policy is pivotal to enhancing national competitiveness for global value chain. This research investigates an SME‐Inclusive public‐private AI innovation network over time in the U.S. context (1991–2023), revealing how a government's demand‐based innovation policy bolsters technological prowess through isomorphism and ...
Jiyoon An
wiley   +1 more source

Environmental Mycotoxins and Brain Health: Protective Role of Bromelain Against Fumonisin B1 in SH‐SY5Y Cells

Environmental Toxicology, EarlyView.
ABSTRACT Fumonisin B1 (FB1), a mycotoxin commonly found in contaminated food and feed, has been increasingly implicated in neurotoxicity, although its mechanisms remain poorly understood. This study investigates the neurotoxic potential of FB1 in human SH‐SY5Y neuroblastoma cells, both undifferentiated and RA‐differentiated, and evaluates the ...
Gianluca Antonio Franco, Francesca Inferrera, Nicla Tranchida, Davide Di Paola, Roberta Fusco, Salvatore Cuzzocrea, Enrico Gugliandolo   +6 more
wiley   +1 more source

Cytogenotoxic Effects of Fluopyram in Allium cepa Root Cells Involving Microtubule Disruption

Environmental Toxicology, EarlyView.
ABSTRACT Fluopyram is a next‐generation fungicide widely used in agriculture; however, its persistence in soils and mobility toward aquatic systems have raised concerns regarding potential ecotoxicological risks. This study evaluated the cytogenotoxic effects of a commercial fluopyram‐based pesticide formulation on Allium cepa root meristem cells ...
Carlos Filipe Camilo‐Cotrim, Natanael Alves da Silva, Gabriela Gomes Lima, Igor Rodrigues Vasconcelos, Luciana Souza Ondei, Elisa Flávia Luiz Cardoso Bailão, Antônio Sérgio Nakao de Aguiar, Marcelino Benvindo‐Souza, Leonardo Luiz Borges, Virgínia Damin, Luciane Madureira Almeida   +10 more
wiley   +1 more source

A Multi‐Analytical Campaign on Reused Medieval Musical Parchment From the Archivio di Stato di Siena (Italy)

X-Ray Spectrometry, EarlyView.
ABSTRACT In this study, a non‐invasive, multi‐analytical approach combining hypercolorimetric multispectral imaging (HMI), stereomicroscopy, X‐ray fluorescence (XRF) spectroscopy, principal component analysis (PCA) and X‐ray radiography (RX) is used to investigate three reused musical parchment fragments dating from the late 14th or early 15th century ...
Mario Gentile, Chiara Delledonne, Michela Albano, Eleonora Verni, Antonio Calvia, Chaehoon Lee, Marco Malagodi, Giacomo Fiocco   +7 more
wiley   +1 more source

Herbivore and mesocarnivore carcasses trigger divergent short‐term changes in soil properties

Journal of Animal Ecology, EarlyView.
Scavengers reshape nutrient cycles in soils under carrion. Compared to herbivore carcasses, smaller but longer‐lasting carnivore remains boost nutrient levels and microbial activity in dry soils. Abstract Animal corpses act as pulses of organic matter (OM) and serve a key zoogeochemical role by providing localized nutrient inputs to soils and thereby ...
Adrián Colino‐Barea, Fuensanta García‐Orenes, Zebensui Morales‐Reyes, Moisés Gonzálvez, Carlos Martínez‐Carrasco, Marcos Moleón, Daniel Redondo‐Gómez, Evan A. N. Marks, Minerva García‐Carmona, Victoria Arcenegui, José Carlos Huerta‐del‐Bosque, Adrián Orihuela‐Torres, Santiago Soliveres, Sofia Albolafio, Esther Sebastián‐González, José Antonio Sánchez‐Zapata   +15 more
wiley   +1 more source

A New Playbook: State‐Driven Solutions for Resilient Health Data

The Milbank Quarterly, EarlyView.
Policy Points Disruptions to federal health data infrastructure threaten states’ ability to identify health disparities, target interventions, and evaluate programs, making state‐level investment in data infrastructure and systems especially urgent. States can build resilient, equity‐centered data systems by enacting data disaggregation legislation ...
NINEZ A. PONCE, RITI SHIMKHADA, TARA BECKER, SUSAN BABEY, A.J. SCHEITLER   +4 more
wiley   +1 more source

The Edification of Manuela Xiqués: Slavery, Finance, Biography, and the Construction of Modern Barcelona

Gender &History, EarlyView.
ABSTRACT An analysis of the dual biographies, economic and domestic, of Manuela Xiqués, an enslaver from nineteenth‐century Cuba and Spain, deepens our understanding of the role of European and Creole women in the nineteenth‐century Atlantic. This essay foregrounds the role of literature, namely family biography, as a locus of the processes of ...
Lisa Surwillo, Martín Rodrigo Alharilla
wiley   +1 more source

The Timely Rise of a Teenage Reformer: Youth Revolt, Feminism and the Struggle for a ‘New Sexual Morality’ at the Dawn of the Spanish Second Republic

Gender &History, EarlyView.
ABSTRACT The contributions of propagandist and writer Hildegart (1914–1933) to Spanish cultural life are overshadowed by accounts of her unusual upbringing and violent death. This article examines the conditions that enabled the teenager to become a prominent voice for feminism and sexual reform on the eve of Spain's Second Republic (1931–1939).
Micaela Pattison
wiley   +1 more source