Results 181 to 190 of about 129,549 (262)

Investigation of eosin Y as a colorimetric sensor for the detection of fentanyl hydrochloride and fentanyl freebase

open access: yesJournal of Forensic Sciences, EarlyView.
Abstract The increasing prevalence of fentanyl within the illegal global drug market underscores the need for rapid, low‐cost, and straightforward detection methods. Eosin Y demonstrates a measurable color change in the presence of fentanyl, making it a promising candidate for colorimetric sensing and preliminary identification of fentanyl ...
Alan J. Zhou   +4 more
wiley   +1 more source

What Causes Geographic Variation in Drug Prescribing? Evidence from Physician Migration

open access: yesThe RAND Journal of Economics, EarlyView.
ABSTRACT In this article, we examine the importance of individual physicians in explaining the significant variation in prescription drug spending in Medicare Part D. By tracking prescribing behavior before and after physician relocations, we find that movers' prescribing converges toward the average of their new location.
David Beheshti, Seth Neller
wiley   +1 more source

Decarbonising Respiratory Care: The Impact of a Low‐Carbon Salbutamol Pressurised Metered‐Dose Inhalers

open access: yesAllergy, EarlyView.
Healthcare systems contribute up to 5% of global GHG emissions, with inhalers contributing a proportion of these. The carbon footprint of current salbutamol inhalers (pMDI with HFA‐134a propellant and DPI) and a planned salbutamol pMDI with low‐GWP propellant HFA‐152a was quantified across seven countries.
James King   +7 more
wiley   +1 more source

Proteomic and Transcriptomic Signatures of Poor Asthma Symptom Control in the U‐BIOPRED Cohort

open access: yesAllergy, EarlyView.
No stable features were identified as associated with asthma symptom control in transcriptomics or sputum proteomics. Higher TWEAKR/TNFRSF12A and MBL/MBP‐C serum levels increased the odds of uncontrolled symptoms, while higher MK08/MAPK8 and CD5L serum levels decreased the odds, after adjustment for clinical variables.
Joana Antão   +294 more
wiley   +1 more source

MAIT Cells Suppress IgE‐Mediated Asthma via IFNγ‐Dependent B Cell Regulation

open access: yesAllergy, EarlyView.
In this study, we demonstrate that MAIT cell antagonism during sensitization and challenge with HDM worsens the development of airway hyperreactivity without effects on type 2 or 17 associated cytokine production or lung inflammation. Rather, MAIT cells appear to regulate HDM‐induced asthma through direct inhibition of IgE production.
Angela M. Cannata   +6 more
wiley   +1 more source

Magnetic Resonance Imaging Evaluation of Functional Differences Between In Vivo Human Kidneys and Discarded Human Kidneys During Ex Vivo Normothermic Machine Perfusion

open access: yesArtificial Organs, EarlyView.
Comparative MRI of in vivo kidneys and ex vivo donor kidneys during NMP revealed marked physiological differences and limited correspondence with conventional perfusion or injury metrics. These distinct ex vivo MRI signatures emphasize the need to consider parameters beyond conventional in vivo functional markers when assessing organ viability during ...
Tim L. Hamelink   +12 more
wiley   +1 more source

Clinical Burden of Symptomatic HEV‐3 Infection in Southern Spain

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
Clinical burden of symptomatic HEV‐3 infection in southern Spain. Between 2022 and 2025, 1124 patients with acute hepatitis, defined as ALT ≥ 3 times the upper limit of normal and negative screening for HAV, HBV, HCV, EBV and CMV, were evaluated in Andalusia.
María Casares‐Jimenez   +14 more
wiley   +1 more source

Wari Lithic Technology on the Northern Coast of the Andes: Geochemical, 2D Geometric Morphometric, and Technological Analyses of Obsidian Bifaces From San José de Moro

open access: yesArchaeometry, EarlyView.
ABSTRACT This study examines Wari obsidian production in a cache of 39 bifaces found at the Late Moche site of San José de Moro (Jequetepeque Valley, North Coast of Peru, 700–850 ad). Portable X‐ray fluorescence, geometric morphometric, and technological analyses were used to investigate raw material provenance and bifacial production.
Antonio Pérez‐Balarezo   +2 more
wiley   +1 more source

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