Results 31 to 40 of about 1,282,751 (309)

Nicotinamide riboside and pterostilbene reduces markers of hepatic inflammation in NAFLD: A double‐blind, placebo‐controlled clinical trial

open access: yesHepatology, EarlyView., 2022
NRPT 1X reduces ALT and ceramide 14:0 in 65% of subjects as compared to only 28% in the placebo group. Abstract Background and Aims The prevalence of NAFLD is increasing globally and on a path to becoming the most frequent cause of chronic liver disease. Strategies for the prevention and treatment of NAFLD are urgently needed.
Ryan W. Dellinger   +7 more
wiley   +1 more source

Archaeological and Historical Assessment of Brackenridge Park City of San Antonio, Texas [PDF]

open access: yes, 1979
During the last weeks of December 1976, an archaeological and historical survey was conducted within the boundaries of Brackenridge Park, San Antonio, Texas, to inventory and assess all identifiable prehistoric and historic remains.
Fox, Anne A., Katz, Susanna R.
core   +2 more sources

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Equal, equitable, or optimal : a comparative analysis of the regional policies and financial structures impacting residential solar adoption [PDF]

open access: yes, 2018
Diversification of energy production is increasingly important as concerns over emissions, energy independence and fuel costs emerge. As such, policies and incentive structures have been put in place by both federal and local government to increase solar
Poteet, Erin
core   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

421 Specific cephalosporin antibiotics deplete tumor PD-L1 to inhibit DNA damage sensing and sensitize to Chk1 inhibitors in vivo

open access: yesJournal of Clinical and Translational Science, 2022
OBJECTIVES/GOALS: Tumor PDL1 signals to immune cells for tumor immune evasion but has cell-intrinsic signals that promote tumor virulence. We identify novel tumor PDL1 depleting drugs (PDDs) to interrupt tumor-intrinsic PDL1 signals and sensitize tumors ...
Clare Murray   +6 more
doaj   +1 more source

Remarks in San Antonio, Texas [PDF]

open access: yes, 1984
Speech for campaign rally at San Antonio, Texas. References Texas Democratic candidates and politicians.https://ir.lawnet.fordham.edu/vice_presidential_campaign_speeches_1984/1000/thumbnail ...
Ferraro, Geraldine
core   +1 more source

An Archaeological Survey of the South Salado Creek Greenway: Rigsby Avenue to Southside Lion\u27s Park East, San Antonio, Bexar County, Texas [PDF]

open access: yes, 2008
In October and November of 2007, The Center for Archaeological Research (CAR) of The University of Texas at San Antonio conducted an intensive pedestrian archaeological survey of the South Salado Creek located in San Antonio, Bexar County, Texas.
Kemp, Leonard, Moses, Bruce K.
core   +2 more sources

Plasma Proteomic Signatures for Alzheimer's Disease: Comparable Accuracy to ATN Biomarkers and Cross‐Platform Validation

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background There is growing recognition of the potential of plasma proteomics for Alzheimer's Disease (AD) risk assessment and disease characterization. However, differences between proteomics platforms introduce uncertainties regarding cross‐platform applicability.
Manyue Hu   +9 more
wiley   +1 more source

Understanding Questions and Concerns Regarding COVID-19 and the COVID-19 Vaccine Among Populations Presenting at a COVID-19 Vaccine Clinic Hub: A Qualitative Study

open access: yesJournal of Primary Care & Community Health, 2022
Background: Skepticism among the public surrounding the COVID-19 vaccine is still prevalent despite vaccine-positive communication and many Americans having already received the vaccine.
Hari N. Krishnakumar   +13 more
doaj   +1 more source

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