Results 31 to 40 of about 4,129,026 (254)

Real‐world effectiveness and safety of secukinumab in giant cell arteritis: an Italian multicentre cohort study

open access: yesArthritis Care &Research, Accepted Article.
Objective The objective of this study was to evaluate the real‐world effectiveness and safety of secukinumab in giant cell arteritis (GCA) patients. Methods This multicentre retrospective study included patients with GCA who received secukinumab at 14 Italian centres with at least 6 months of follow‐up.
Luca Iorio   +29 more
wiley   +1 more source

Analgesic Effects of Oxycodone in Combination With Risperidone or Ziprasidone: Results From a Pilot Randomized Controlled Trial in Healthy Volunteers

open access: yesFrontiers in Pain Research, 2022
Background and ObjectivesPatients taking opioids are at risk of developing dependence and possibly abuse. Given the role of the mesolimbic dopamine system in opioid reward, blocking dopamine D2 receptors should limit the abuse liability of opioid ...
Ameet S. Nagpal   +8 more
doaj   +1 more source

3D Nanorod‐Shaped Binder‐Free Ni1−xFexCo2O4 Anodes Demonstrate High Performance and Stable Operation Under Accelerated Stress Tests in Anion Exchange Membrane Water Electrolysis

open access: yesAdvanced Materials Interfaces, EarlyView.
3D shaping of Ni1‐xFexCo2O4 spinel electrocatalyst to form high aspect ratio nanorods, made of 25 nm grain size particles and directly grown on Nickel felt, is proposed to improve the performance of industrial catalysts based on group‐VIII transition‐metal oxides.
Ataollah Niyati, Ombretta Paladino
wiley   +1 more source

Evaluation of healing at molar extraction sites with ridge preservation using a non‐resorbable dense polytetrafluoroethylene membrane: A four‐arm cohort prospective study

open access: yesClinical and Experimental Dental Research, 2021
Objectives To examine ridge dimensional changes and histologic parameters of healing when ridge preservation (RP) was performed at molar sites using dense polytetrafluoroethylene (dPTFE) membrane alone, without a bone graft. Material and Methods Eighteen
Arwa M. Al Hugail   +8 more
doaj   +1 more source

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

open access: yesAdvanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes   +14 more
wiley   +1 more source

Beyond the Oxo‐Wall: Synthesis and Reactivity of a Six‐Coordinate Formally CoIV‐Oxo Complex

open access: yesAngewandte Chemie, EarlyView.
We present the first example of a six‐coordinate formally Co(IV)‐oxo complex, [Co(TQA)(O)(OH)]+ (1), which exists as an admixture of CoIV‐oxo and CoIII‐oxyl resonance structures. Complex 1 is capable of performing oxygen atom transfer reactions and abstracting moderately strong hydrogen atoms at rates faster than other characterized CoIV‐oxo compounds.
Jason Shearer   +6 more
wiley   +2 more sources

Optically Tunable Threshold Switching and Thermally Activated Transport in Planar Ag/MAPbI3 Thin Single‐Crystal Devices

open access: yesAdvanced Science, EarlyView.
Planar Ag/MAPbI3 thin single‐crystal halide perovskite devices show ultralow dark current and optically tunable threshold switching. Illumination enhances the polarity‐dependent hysteresis and shifts the switching voltage, whereas temperature‐dependent measurements reveal thermally activated, contact‐limited transport, underscoring the central role of ...
Ofelia Durante   +16 more
wiley   +1 more source

Utility of Three-Dimensional Printed Model in Biventricular Repair of Complex Congenital Cardiac Defects: Case Report and Review of Literature

open access: yesChildren, 2022
Heterotaxy is a rare syndrome associated with cardiac complexity, anatomic variability and high morbidity and mortality. It is often challenging to visualize and provide an accurate diagnosis of the cardiac anatomy prior to surgery with the use of ...
Lauren Gabriel Betancourt   +4 more
doaj   +1 more source

A Drug‐Gated, Modular STAb‐T Immunotherapy With External Control

open access: yesAdvanced Science, EarlyView.
Engineered STAb‐TON cells act as programmable living factories that continuously secrete inactive antibody modules, which assemble extracellularly into a functional T cell engager only upon small‐molecule administration. This externally controlled platform enables reversible, on‐demand regulation of antitumor immunity, establishing a new paradigm for ...
Susana Luengo‐Arias   +23 more
wiley   +1 more source

Five Students of San Antonio Female College

open access: yes, 1915
Photograph of five students from San Antonio Female College, taken around 1915. They are identified on the back of the photograph as: [back row, left to right] Ann DePraslin, Lois Goddard, Viola Drew; [front row, left to right] Frances Lyles, Helen ...
San Antonio Female College
core   +1 more source

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