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Results 141 to 150 of about 2,790,995 (275)

Toward Harmonizing Quantification of Dopamine Neuron Imaging Biomarkers in Parkinson's Disease: The Centamine Scale

Annals of Neurology, EarlyView.
Objective Dopaminergic imaging is a key biomarker for both the investigation of the biology of Parkinson's disease and related synucleinopathies and the evaluation of potential therapies in clinical trials. This work presents a harmonized approach for quantifying dopaminergic molecular imaging tracers, such as [123I]ioflupane (dopamine transporter scan
Zhen Fan +174 more
wiley +1 more source

A Novel Condom Distribution Program for County Jail Prisoners [PDF]

, 2008
The Center for AIDS Prevention Studies (CAPS), in collaboration with the Center for Health Justice, the Forensic AIDS Project, and the San Francisco Sheriff's Department, conducted a feasibility study of a novel method of providing condoms to prisoners ...
Kate Monico Klein, Mary Sylla, Olga Grinstead Reznick +2 more
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Natural Language Processing for Radiation Oncology: Personalizing Treatment Pathways

Pharmacogenomics and Personalized Medicine
Hui Lin,1,2 Lisa Ni,1 Christina Phuong,1 Julian C Hong1,3,4 1Department of Radiation Oncology, University of California San Francisco, San Francisco, CA, USA; 2UC Berkeley-UCSF Graduate Program in Bioengineering, University of California, Berkeley and ...
Lin H, Ni L, Phuong C, Hong JC
doaj

When Does Alzheimer's Disease Start? Plasma Aβ42/40 Assays Show Steep Changes at Aβ‐PET Centiloid 15, Mean Age of 66 Years

Annals of Neurology, EarlyView.
Objective Sporadic late‐onset Alzheimer's disease (AD) is characterized by a long pre‐clinical phase where amyloid‐beta (Aβ) and tau begin to accumulate in the brain. The primary objective was to determine the age at which AD starts by finding the average population age when both positron emission tomography (PET) Aβ (Aβ‐PET) and plasma Aβ42/40 become ...
Rodrigo Cánovas +29 more
wiley +1 more source

Tau Pathology in Alzheimer's Disease Uniquely Affects Sulcal Depths

Annals of Neurology, EarlyView.
Objective Though it is widely known that tau deposition affects brain structure, the precise localization of these effects is poorly understood, especially in relation to gyral and sulcal anatomy. We investigated whether tau pathology in Alzheimer's disease (AD) preferentially affects sulci, and particularly sulcal depths.
Samira A. Maboudian +10 more
wiley +1 more source

Individualized Atrophy‐Based Prediction of Dementia Progression in Familial Frontotemporal Lobar Degeneration With Bayesian Linear Mixed‐Effects Modeling

Annals of Neurology, EarlyView.
Objective Age of symptom onset is highly variable in familial frontotemporal lobar degeneration (f‐FTLD). Accurate prediction of onset would inform clinical management and trial enrollment. Prior studies indicate that individualized maps of brain atrophy can predict conversion to dementia in f‐FTLD.
Shubir Dutt +82 more
wiley +1 more source

Blood Lactate as a Prognostic Biomarker for Survival and Weight Loss in Amyotrophic Lateral Sclerosis: An Exploratory–Validation Study

Annals of Neurology, EarlyView.
Objective Lactate is increasingly recognized as an energy substrate, but its relevance to amyotrophic lateral sclerosis (ALS) remains unclear. We examined whether blood lactate is associated with survival and weight loss in ALS. Methods This retrospective study included an Australian exploratory cohort and a Japanese validation cohort with clinical ...
Ryutaro Nakamura +8 more
wiley +1 more source

A Phase 2 Trial of Hydroxychloroquine in Individuals at Risk for Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Individuals with serum elevations of anti–cyclic citrullinated peptide (anti‐CCP) antibodies are at increased risk for future rheumatoid arthritis (RA). No pharmacologic interventions have been approved for the prevention of RA in such at‐risk individuals.
Kevin D. Deane +33 more
wiley +1 more source

Erector Spinae Plane versus Pectoralis Nerve Block for Mastectomy in Cancer Patients: A Retrospective, Multicenter Cohort Study

Journal of Pain Research
Edward N Yap,1,2 Julia Wei,3 Curtis Darling,4 Elizabeth Linehan,5 Matthias Behrends,2 Kevin P Ng6,7 1Department of Anesthesia, The Permanente Medical Group, Kaiser Permanente South San Francisco, South San Francisco, CA, USA; 2Department of Anesthesia ...
Yap EN +5 more
doaj

Remember the Fillmore: The Lingering History of Urban Renewal in Black San Francisco

, 2012
In the summer of 2008, I moved to San Francisco, California. I lived in the city for three months. As a researcher, my objective was to learn more about Mayor Gavin Newsome’s African-American Out-Migration Task Force.
Jackson, Christina, Jones, Nikki
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