Results 181 to 190 of about 2,790,995 (275)

Advancing Pharmacometrics in Africa: Insights and Perspectives From the 2025 Pharmacometrics Africa Conference

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Pharmacometrics (PMX) in Africa has transitioned from foundational capacity‐building to job creation, scientific leadership, regulatory influence, and health innovation. To accelerate this progress, the 2025 Pharmacometrics Africa Conference (PMXAC‐2025) convened key stakeholders to consolidate the continental PMX community, review progress in local ...
Babatunde Ayodeji Adeagbo   +12 more
wiley   +1 more source

Advances in Human Mass Balance Studies: An IQ Consortium Perspective on Current Practices and Emerging Trends

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Human radiolabeled mass balance studies are crucial for comprehensively characterizing the absorption, distribution, metabolism, and excretion (ADME) of investigational drugs, providing essential data for drug development, regulatory evaluation, and product labeling.
Jason Boer   +24 more
wiley   +1 more source

Trends in Uropathogenic <i>Escherichia coli</i> Genotype and Antimicrobial Resistance From 2019 to 2022 in a San Francisco Public Hospital Network. [PDF]

open access: yesOpen Forum Infect Dis
Joyce S   +10 more
europepmc   +1 more source

A Computational Workflow for Cell Line Profiling by Imaging Mass Cytometry

open access: yesCytometry Part A, EarlyView.
ABSTRACT In single‐cell spatial phenotyping biology, imaging mass cytometry (IMC) stands out as a cutting‐edge, highly multiplexed technology driving discoveries across various disease areas. In vitro profiling relies on tumor‐derived cancer cell lines, known for their diverse morphologies and phenotypes.
Alexandre Bouzekri   +2 more
wiley   +1 more source

Neighborhood built environment, psychosocial stressors, and telomere length of birth parents and their newborns from San Francisco, California. [PDF]

open access: yesJ Expo Sci Environ Epidemiol
Cushing LJ   +8 more
europepmc   +1 more source

Seismic analysis and design of tunnels within fault ground: A review

open access: yesDeep Underground Science and Engineering, EarlyView.
The research methods of seismic response of tunnels within fault ground, including field investigations, analytical solutions, physical experiments, and numerical simulations, and seismic countermeasures are discussed. The present study examines the shortcomings and limitations of the current research and design, and puts forward proposals for future ...
Xingda Wang   +6 more
wiley   +1 more source

Differential sensitivity of midline development to mitosis during and after primitive streak extension

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Midline establishment is a fundamental process during early embryogenesis for Bilaterians. Midline morphogenesis in non‐amniotes can occur without mitosis, through Planar Cell Polarity (PCP) signaling. By contrast, amniotes utilize both cellular processes for developing the early midline landmark, the primitive streak (PS).
Zhiling Zhao, Rieko Asai, Takashi Mikawa
wiley   +1 more source

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