Results 191 to 200 of about 832,436 (311)

No strings attached: a mixed methods evaluation of the acceptability of the San Francisco Abundant Birth Project, a perinatal guaranteed income program. [PDF]

BMC Public Health
De La Cruz MM, Arteaga S, Hubbard EM, Reed RD, Cotton-Curtis W, Taylor M, Powell B, Coats A, Bell S, Edwards P, Chand M, Roberts T, Chambers Butcher B, Karasek D, Malawa Z, Gomez AM.   +15 more
europepmc   +1 more source

“The Most Difficult Conversations We Have”: Resident Experiences With Pediatric Neuroprognostication

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Objective Pediatric neuroprognostication is often complicated by uncertainty and embedded in high‐stakes medical decisions. For child neurology residents, participation in neuroprognostication can represent key learning experiences but also comes with emotional and ethical challenges, which poses a risk of moral distress.
Grant L. Lin, Beatrice D. White, Shelby D. Burk, Jessica A. Moriarty, David B. Mauser, Claire E. Wakefield, Courtney J. Wusthoff, Justin N. Baker   +7 more
wiley   +1 more source

Participant Perspectives in an HIV Treatment Interruption Study in San Francisco, United States. [PDF]

AIDS Res Hum Retroviruses
Nguyen E, Korolkova A, Ahmed A, Meanley S, Dee L, Hussain M, Wan F, Hoh R, Rodriguez A, Figueroa T, Cohn LB, Deeks SG, Peluso MJ, Eskaf S, Sugarman J, Sauceda JA, Dubé K.   +16 more
europepmc   +1 more source

Characterization of Lysosomal Hydrolases and Transporters and Their Age‐Dependent Variability: Relevance to Drug Metabolism and Transport of Small Molecule and Biologic Drugs

Clinical Pharmacology &Therapeutics, EarlyView.
Lysosomes play a key role in the accumulation, catabolism, and transport of endogenous and exogenous metabolites and proteins and are involved in drug metabolism and prodrug activation. However, the protein abundance and interindividual variability of lysosomal drug‐metabolizing enzymes and transporters (DMETs) remain underexplored.
Darshak Gadara, Dilip Kumar Singh, Sandhya Subash, Guihua Yue, Deepak Ahire, Chris Bohl, Maciej Czerwinski, Stephanie Helmstetter, Scott Heyward, Robert S. Jones, Cyrus Khojasteh, Ryota Kikuchi, Priyanka Kulkarni, Bin Ma, Bernard Murray, Chris Seib, Bill Smith, David M. Stresser, Mitchell E. Taub, Ting Wang, Bhagwat Prasad   +20 more
wiley   +1 more source

Accessing acute care hospitals in the San Francisco Bay Area after a major hayward earthquake. [PDF]

Nat Commun
Ceferino L, Kukunoor C, Zhao J, Mao D, Xu X, Wu J, Zsarnóczay A.   +6 more
europepmc   +1 more source

Digital Transformation of Medicines Regulation in Africa—Perspectives from a Stakeholder Convening

Clinical Pharmacology &Therapeutics, EarlyView.
Regulatory authorities worldwide are developing strategies to integrate artificial intelligence (AI) into the lifecycle of health products, technologies, and medicines. While regulators share goals of improving efficiency, strengthening decision‐making, and protecting public health, their approaches differ according to institutional structures ...
Christelna Reyneke, Boitumelo Semete‐Makokotlela, Varnika Singh, Khanyisile Nkuku, Madelein Terblanche, Ezekiel T Mukanga, Nancy Ngum, Kudakwashe Dandajena, McNeil Chimus Mhango, Paulyne Wairimu, John Mwangi, Dominique Lagrave, Goonaseelan (Colin) Pillai   +12 more
wiley   +1 more source

Associations Between Seafood Consumption and Serum PFAS Levels Among Asian/Pacific Islanders in the San Francisco Bay Area, California. [PDF]

Expo Health
Chen K, Beglarian E, Kauffman D, Tang IW, Saephan F, Park JS, Smith S, Choe KY, She J, Wu N, Attfield KR.   +10 more
europepmc   +1 more source

Disentangling Sex Differences in Sulfonylurea Drug Response With Genome‐Wide Association Studies in Individuals With Type 2 Diabetes

Clinical Pharmacology &Therapeutics, EarlyView.
A sex‐stratified genome‐wide association study of sulfonylurea response identified sex‐specific genetic loci associated with HbA1c reduction in individuals with type 2 diabetes. Replication and functional validation supported a male‐specific association at the TMEM64/NECAB1 locus, highlighting the potential of sex‐informed pharmacogenomics to advance ...
Joseph H. Breeyear, John S. House, Mark Kvale, Stella Nam, Farida S. Akhtari, Hetal S. Shah, Monique M. Hedderson, Kathleen M. Giacomini, Josyf C. Mychaleckyj, Alessandro Doria, Michael J. Wagner, Josephine H. Li, Sook Wah Yee, John B. Buse, Richard P. Woychik, Daniel M. Rotroff, Alison A. Motsinger‐Reif   +16 more
wiley   +1 more source

The role of stigma in impeding implementation of harm reduction services in San Francisco. [PDF]

SSM Qual Res Health
Akiba CF, Megerian CE, Chung EO, Morris T, Wenger LD, Suen LW, Lambdin BH, Kral AH.   +7 more
europepmc   +1 more source