Results 191 to 200 of about 49,451 (306)

A game theoretical analysis of economic sanction

open access: yes
Economic sanction has been widely used and increasingly a popular tool in maintaining peace and political stability in the world. The use of economic sanction, as opposed to the use of military power, to punish target countries have been supported by the
Shidiqi, khalifany ash   +1 more
core  

Juvenile sanctions for young adult offenders in the Netherlands: an opportunity for rehabilitation? [PDF]

open access: yesChild Adolesc Psychiatry Ment Health
Prop LJC   +4 more
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Program Evaluation : Social Studies : Elementary Cycle Two

open access: yes, 1993
Québec (Province). Direction de la sanction des études
core  

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

〈Articles〉Internal sanction or external sanction?

open access: yes〈Articles〉Internal sanction or external sanction?
[Abstract] This work studies the relative merits of two distinct management policies by which a manager induces a worker's effort, based on the work norm. One policy is to induce the worker to experience disutility (guilt) if he shirks by making him internalize a sanction through an educational program. The other policy is to give him an incentive from
openaire  

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