Results 61 to 70 of about 167,140 (312)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
About the disregard of legal entity doctrine in Brazilian anti-corruption act (Law no. 12,846/2013)
Revista de Direito Econômico e Socioambiental, 2020 The purpose of this review is to analyze the disregard of the legal entity provision in the Brazilian Anti-Corruption Law (Law no. 12,846/13), intended to sanction juristic persons for harmful acts against the Public Administration.
José Sérgio da Silva Cristóvam +1 more
doaj +1 more source
Policy Framework to Strengthen Community Corrections [PDF]
, 2008 Details policy options for implementing reforms and best practices for reducing recidivism, including evidence-based supervision practices, earned compliance credits for offenders, and performance measurements and incentive funding for ...
core
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Jurnal Media Hukum, 2012 Corruption in the procurement of goods and services cannot be eradicated only by a single criminal law instrument. The punishment theory, which aims at making the corruptors or people who want to do corruption scared and prevent the from corruption, is ...
Amiruddin Amiruddin
doaj
Legal Responsibilities of Taxpayers Intentionally Not Reporting SPT Correctly
Yurisdiksi: Jurnal Wacana Hukum dan SainsThe source of revenue in Indonesia was divided into two: domestic revenue and foreign revenue. In this regard, tax was one of the sources of domestic revenue. The tax was also one of the largest revenue sources for Indonesia.
Rogantino Sampetua Pasaribu
doaj +1 more source
Responding to Terrorism: How Must a Democracy Do It? A Comparison of Israeli and American Law [PDF]
, 2003 This Comment compares the Israeli and American laws that sanction controversial responses to terrorism. It discusses criticisms of these laws with respect to human rights violations and how, if at all, the two governments strive to preserve their law ...
Grebinar, Jonathan
core +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Sanksi Administratif terhadap Ppat Atas Kelalaian Pengawasan Pembayaran Bphtb dalam Pembuatan Akta Peralihan Hak Atas Tanah [PDF]
, 2016 Government Regulation No. 37/1998 on PPAT (Official Empowered to Draw up Land Deeds) states that in the case of transferring of title on land and building, PPAT/Notary has the authority to draw up a certificate and validates the rights, and he also has ...
SITOMPUL, S. Y. (SRI)
core
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source