Results 81 to 90 of about 167,140 (312)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Pertanggungjawaban Pidana Bank dalam Pelanggaran Kegiatan Operasional Didasarkan pada Undang-Undang Nomor 10 Tahun 1998

open access: yesDialogia Iuridica, 2017
Banks are the intermediation institutions which have important role in economic of a nation. In order to supervise and monitor bankong activities, government has issued Law Number 10 of 1998 on amandement of Law Number 7 of 1992 on banking which is ...
Johannes Ibrahim, Hassanain Haykal
doaj   +1 more source

Analysis of Strategies Designed to Reduce Sales of Alcohol and Tobacco to Underage Persons: A Preliminary Report [PDF]

open access: yes, 2012
Alaska has one of the highest per capita alcohol consumption rates in the nation, and the prevalence of alcohol dependence and alcohol abuse at 14 percent is twice the national average of seven percent. Of special concern is the prevention of alcohol use
Parker, Khristy, Rivera, Marny
core  

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

LEGAL STATUS AND ACTIVITIES OF BODIES AUTHORISED TO IMPOSE FINANCIAL ADMINISTRATIVE SANCTIONS

open access: yesBaltic Journal of Economic Studies
The existence of a system of financial liability measures is a common occurrence in market economies. Despite their considerable motivational potential, financial administrative sanctions constitute a significant interference with human rights ...
Tetiana Kolomoiets   +2 more
doaj   +1 more source

What triggers school improvement? Evidence from a court induced change in Florida's A+ accountability plan [PDF]

open access: yes, 2013
In 2006, the Florida Supreme Court ended the state funded voucher program which allowed students of repeatedly failing public schools to transfer to a private school.
Siegler, Benedikt
core  

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Arti penting dan implementasi hukum perizinan dalam bidang lingkungan hidup di Indonesia

open access: yesJurnal Civics: Media Kajian Kewarganegaraan, 2005
Licensing represent one of the medium of yuridis vitally administrative in execution of effort activity of development, especially in its bearing with continuation of ability of environment in this Indonesia Circumstance to earn us of the understand ...
Eny Kusdarini
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Constraints of Bee Keepers Uttarakannada [PDF]

open access: yes, 2013
A detailed study on beekeeping and beekeepers of Uttarakannada showed major administrative, technical, and financial constraints. Lack of subsidy to local bee boxes (17.34%), tax on extractor and bee box (18.8%), lack of supply of colonies along with ...
Poornima, B.S.
core  

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