Results 151 to 160 of about 745,330 (389)

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Treason, Terrorism and United States' Citizens: Sanctioned Assassinations? [PDF]

, 2017
Chandrika Kelso
openalex   +1 more source

Innocent or not-so-innocent bystanders: evidence from the gravity model of international trade about the effects of UN sanctions on neighbor countries [PDF]

This paper examines two theories about the effects of UN sanctions on trade flows between land neighbors of the target country and the rest of the world.
Slavi T. Slavov
core  

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Optimal unemployment insurance with monitoring and sanctions [PDF]

This paper analyzes the design of optimal unemployment insurance in a search equilibrium framework where search effort among the unemployed is not perfectly observable. We examine to what extent the optimal policy involves monitoring of search effort and
Boone, Jan, Fredriksson, Peter, Holmlund, Bertil, van Ours, Jan   +3 more
core   +3 more sources

Economic sanctions in world politics and science on international relations: relevant theoretical-methodological approaches

, 2020
Yan Nikolaevich Shevchenko, Dmitriy Viktorovich Mukhamadeev   +1 more
openalex   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Sanctions and the Geopolitical Commission: The War over Ukraine and the Transformation of EU Governance

European Papers
(Series Information) European Papers - A Journal on Law and Integration, 2023 8(3), 1125-1130 | European Forum Insight of 15 January 2024 | (Table of Contents) I. Introduction: the war in Ukraine and sanctions. - II. Sanctions formulation.
Clara Portela
doaj   +1 more source

A Nuclear Test for Diplomacy: Iran and the (New) EU-US Sanctions Debate

, 2018
Ioana Constantin-Bercean, Andreea Stretea, Andreea Stretea, Facultatea de Studii Europene, UBB Cluj-Napoca   +3 more
openalex   +1 more source