Results 1 to 10 of about 220,374 (322)

Functional genomics in sand fly-derived Leishmania promastigotes. [PDF]

PLoS Neglected Tropical Diseases, 2019
BackgroundLeishmania development in the sand fly gut leads to highly infective forms called metacyclic promastigotes. This process can be routinely mimicked in culture.
Pedro J Alcolea, Ana Alonso, Ricardo Molina, Maribel Jiménez, Peter J Myler, Vicente Larraga   +5 more
doaj   +9 more sources

An overview of the sand fly salivary proteins in vaccine development against leishmaniases [PDF]

Iranian Journal of Microbiology, 2022
Leishmaniases are a group of vector-borne parasitic diseases transmitted through the infected sand flies. Leishmania parasites are inoculated into the host skin along with sand fly saliva.
Shima Fayaz, Fariborz Bahrami, Parviz Parvizi, Pezhman Fard-Esfahani, Soheila Ajdary   +4 more
doaj   +2 more sources

Sand-fly saliva-Leishmania-man: the trigger trio [PDF]

Frontiers in Immunology, 2013
Leishmaniases are worldwide diseases transmitted to the vertebrate host by the bite of an infected sand fly. Sand fly biting and parasite inoculation are accompanied by the injection of salivary molecules, whose immunomodulatory properties are actively ...
Camila I. De Oliveira, Augusto M de Carvalho, Fabiano eOliveira   +2 more
doaj   +4 more sources

Disentangling detrimental sand fly-mite interactions in a closed laboratory sand fly colony: implications for vector-borne disease studies and guidelines for overcoming severe mite infestations [PDF]

Parasites & Vectors
Background Vector sand fly colonies are a critical component of studies aimed at improving the understanding of the neglected tropical disease leishmaniasis and alleviating its global impact.
Chukwunonso O. Nzelu, Claudio Meneses, Christina Bowhay, Iliano V. Coutinho-Abreu, Emily Bennett, Somayeh Bahrami, Brian Bonilla, Shaden Kamhawi, Jesus G. Valenzuela, Nathan C. Peters   +9 more
doaj   +2 more sources

Sexing sand fly pupae (Diptera: Psychodidade: Phlebotominae) [PDF]

Memórias do Instituto Oswaldo Cruz, 2000
We describe a technique to separate male and female pupae of sand flies. This has reduced the labour to separate flies after emergence and also allows the isolation of unmated adults for behavioural and physiological studies.
Beatriz Gomes Brazil, Reginaldo Peçanha Brazil   +1 more
openalex   +7 more sources

The role of phosphoglycans inLeishmania–sand fly interactions [PDF]

Proceedings of the National Academy of Sciences, 2000
Leishmaniapromastigotes synthesize an abundance of phosphoglycans, either attached to the cell surface through phosphatidylinositol anchors (lipophosphoglycan, LPG) or secreted as protein-containing glycoconjugates. These phosphoglycans are thought to promote the survival of the parasite within both its vertebrate and invertebrate hosts.
David L. Sacks, Govind B. Modi, Edgar Rowton, Gérald F. Späth, Linda F. Epstein, Salvatore J. Turco, Stephen M. Beverley   +6 more
openalex   +6 more sources

Molecular Diversity between Salivary Proteins from New World and Old World Sand Flies with Emphasis on Bichromomyia olmeca, the Sand Fly Vector of Leishmania mexicana in Mesoamerica. [PDF]

PLoS Neglected Tropical Diseases, 2016
BACKGROUND:Sand fly saliva has been shown to have proteins with potent biological activities, salivary proteins that can be used as biomarkers of vector exposure, and salivary proteins that are candidate vaccines against different forms of leishmaniasis.
Maha Abdeladhim, Iliano V Coutinho-Abreu, Shannon Townsend, Silvia Pasos-Pinto, Laura Sanchez, Manoochehr Rasouli, Anderson B Guimaraes-Costa, Hamide Aslan, Ivo M B Francischetti, Fabiano Oliveira, Ingeborg Becker, Shaden Kamhawi, Jose M C Ribeiro, Ryan C Jochim, Jesus G Valenzuela   +14 more
doaj   +3 more sources

Leishmania major-Infected Phlebotomus duboscqi Sand Fly Bites Enhance Mast Cell Degranulation [PDF]

Pathogens, 2023
Leishmania parasites infect mammalian hosts through the bites of sand fly vectors. The response by mast cells (MC) to the parasite and vector-derived factors, delivered by sand fly bites, has not been characterized.
Laura Sánchez-García, Armando Pérez-Torres, Marco E. Gudiño-Zayas, Jaime Zamora-Chimal, Claudio Meneses, Shaden Kamhawi, Jesus G. Valenzuela, Ingeborg Becker   +7 more
doaj   +2 more sources

Sand fly evolution and its relationship to Leishmania transmission [PDF]

Memórias do Instituto Oswaldo Cruz, 2000
The evolutionary relationships of sand flies and Leishmania are discussed in this report, which draws distinctions between co-association, co-evolution and co-speciation (or co-cladogenesis). Examples focus on Phlebotomus vectors of Le. infantum and Le. major in the Mediterranean subregion.
P. D. Ready
openalex   +7 more sources

Susceptibility of diverse sand fly species to Toscana virus. [PDF]

PLoS Negl Trop Dis
Toscana virus (TOSV) is an emerging but neglected human pathogen currently circulating around the Mediterranean basin including North Africa. Human illness ranges from asymptomatic or mild flu-like syndromes to severe neurological diseases such as meningitis or meningoencephalitis.
Jancarova M, Polanska N, Thiesson A, Arnaud F, Stejskalova M, Rehbergerova M, Kohl A, Viginier B, Volf P, Ratinier M.   +9 more
europepmc   +5 more sources