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Phlebotomine sand flies are proven or suspected vectors of several pathogens of importance, including leishmaniasis, bartonellosis and sand fly fevers. Although sand flies have a worldwide distribution, there has been limited research published on sand ...
J. Hustedt +4 more
semanticscholar +2 more sources
Background Visceral leishmaniasis (VL) is a deadly disease transmitted by the sand fly Phlebotomus argentipes on the Indian subcontinent, with a promising means of vector control being orally treating cattle with fipronil-based drugs.
David M. Poché +2 more
semanticscholar +2 more sources
River sand supplies are decreasing due to overexploitation and illicit sand mining. One ton of Portland cement production (the main binder in concrete) emits about one ton of carbon dioxide into the atmosphere.
S. Sathvik +6 more
semanticscholar +2 more sources
Functional genomics in sand fly–derived Leishmania promastigotes
Background Leishmania development in the sand fly gut leads to highly infective forms called metacyclic promastigotes. This process can be routinely mimicked in culture. Gene expression–profiling studies by transcriptome analysis have been performed with
P. J. Alcolea +5 more
semanticscholar +2 more sources
Leishmania infection induces a limited differential gene expression in the sand fly midgut
Sand flies are the vectors of Leishmania parasites. To develop in the sand fly midgut, Leishmania multiplies and undergoes various stage differentiations giving rise to the infective form, the metacyclic promastigotes.
Iliano V. Coutinho-Abreu +5 more
semanticscholar +3 more sources
Optimization of sand fly embryo microinjection for gene editing by CRISPR/Cas9 [PDF]
Background Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9 technology has rapidly emerged as a very effective tool for gene editing.
Inés Martín-Martín +4 more
semanticscholar +2 more sources
Leishmania sand fly-transmission is disrupted by Delftia tsuruhatensis TC1 bacteria. [PDF]
Most human pathogenic Leishmania species are zoonotic agents; therefore, sand fly-based control strategies are essential to prevent parasite circulation.
Cecilio P +16 more
europepmc +2 more sources
Genomic analysis of two phlebotomine sand fly vectors of Leishmania from the New and Old World
Phlebotomine sand flies are of global significance as important vectors of human disease, transmitting bacterial, viral, and protozoan pathogens, including the devastating kinetoplastid parasites of the genus Leishmania, the causative agents of diseases ...
Frédéric Labbé +80 more
semanticscholar +1 more source
Chemical control and insecticide resistance status of sand fly vectors worldwide
Background Phlebotomine sand flies are prominent vectors of Leishmania parasites that cause leishmaniasis, which comes second to malaria in terms of parasitic causative fatalities globally. In the absence of human vaccines, sand fly chemical-based vector
S. Balaska +3 more
semanticscholar +1 more source
Formation and three-dimensional architecture of Leishmania adhesion in the sand fly vector
Attachment to a substrate to maintain position in a specific ecological niche is a common strategy across biology, especially for eukaryotic parasites. During development in the sand fly vector, the eukaryotic parasite Leishmania adheres to the stomodeal
R. Yanase +10 more
semanticscholar +1 more source

