Results 81 to 90 of about 19,825 (223)

Exodontia Block Course Evaluation: A Review of the Learning Outcomes, Content, and Assessment Practices at a Dental Faculty in South Africa

European Journal of Dental Education, Volume 30, Issue 2, Page 392-406, May 2026.
ABSTRACT Introduction Regular curriculum renewal ensures relevant and responsive curricula. Skills development courses, such as for dental extraction procedures, require the same rigorous review, as this skill demands both technical proficiencies and a high level of cognition.
Nashreen Behardien, Priscilla Brijlal, Nicolette Vanessa Roman   +2 more
wiley   +1 more source

Sand Fly–Associated Phlebovirus with Evidence of Neutralizing Antibodies in Humans, Kenya

Emerging Infectious Diseases, 2019
We describe a novel virus, designated Ntepes virus (NPV), isolated from sand flies in Kenya. NPV has the characteristic phlebovirus trisegmented genome architecture and is related to, but distinct from, Gabek Forest phlebovirus.
David P. Tchouassi, Marco Marklewitz, Edith Chepkorir, Florian Zirkel, Sheila B. Agha, Caroline C. Tigoi, Edith Koskei, Christian Drosten, Christian Borgemeister, Baldwyn Torto, Sandra Junglen, Rosemary Sang   +11 more
doaj   +1 more source

Leishmania-sandfly interactions [PDF]

Open Journal of Tropical Medicine, 2018
There is a specific association between insect vector species and parasites [1]. The susceptibility or resistance of a species of sandfly to the development of a particular parasite depends on its ability to overcome certain barriers such as the proteolytic enzymes of the midgut, the peritrophic membrane surrounding the blood meal, and excretion of the
openaire   +1 more source

Safety, tolerability and pharmacokinetics of DNDI‐6148, a novel agent for leishmaniasis: A randomized, controlled, single ascending dose study in healthy participants

British Journal of Clinical Pharmacology, Volume 92, Issue 4, Page 1087-1097, April 2026.
Aim The benzoxaborole derivative DNDI‐6148 is an antiparasitic agent with activity against multiple Leishmania protozoan species, including L. infantum and L. donovani, which cause visceral leishmaniasis. We investigated the safety, tolerability and pharmacokinetics of single oral doses of DNDI‐6148 in a randomized, parallel‐group, placebo‐controlled ...
Jean‐Yves Gillon, Sophie Delhomme, Delphine Launay, Séverine Blesson, Stéphanie Braillard, Pegah Maghdooni, Frauke Assmus, Richard Hoglund, Joel Tarning, Sabrina Loyau, Byron Arana, Mathilde Latreille‐Barbier, Yves Donazzolo   +12 more
wiley   +1 more source

Susceptibility of phlebotomine sandflies (Diptera: Psychodidae) collected in the field, to alpha-cypermethrin in four municipalities endemic to leishmaniasis

Revista do Instituto de Medicina Tropical de São Paulo
Although the chemical control against leishmaniasis began in 1953 in Brazil, little information is available on how this strategy has affected populations of phlebotomine sandflies in the field.
Douglas de Almeida Rocha, Andrey José de Andrade, Luciana Reinaldo Moura, Nelder Gontijo Figueiredo, Grasielle Caldas D’Ávila Pessoa, Marcos Takashi Obara   +5 more
doaj   +1 more source

Immunomodulating effects of Phlebotomine saliva in Leishmania infection: Review

EntomoBrasilis, 2018
. The recognized action of some proteins present in the saliva of the phlebotomine dipteran vectors of Leishmaniasis, as modulators of the hemostatic, inflammatory and immune responses during the colonization of the protozoan in the host organism ...
Ivan Brito Feitosa, Wesley Roberto de Aguida, Carolina Bioni Garcia Teles   +2 more
doaj   +1 more source

Brain Involvement in Leishmaniasis

Cell Biochemistry and Function, Volume 44, Issue 4, April 2026.
ABSTRACT Leishmaniasis is a neglected tropical disease caused by infection with the protozoan parasite Leishmania and it is a significant global health problem. The disease has a wide clinical spectrum, from tegumentary leishmaniasis (TL) that encompasses cutaneous (CL), mucosal (ML) and cutaneous‐diffuse (CDL) forms, to the potentially fatal systemic ...
Camila S. Freitas, Eduardo A. F. Coelho, Myron Christodoulides   +2 more
wiley   +1 more source

Visceral Leishmaniasis in Somalia: Diagnosis and Management of a Classic Case in a Resource‐Limited Endemic Setting

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Visceral Leishmaniasis (VL), a severe systemic neglected tropical disease (NTD) caused by Leishmania donovani complex protozoa, poses a significant public health threat, particularly in East Africa, where it is fatal if untreated. Somalia is known to be endemic, but the true burden and programmatic challenges are poorly documented due to long ...
Abdirahman Nuur Hussein, Abdirahman Omer Ali, Ridwan Zakariye Ahmed, Sihaam Mohamed Abdirahman, Ahmed Dek Abdiwahab   +4 more
wiley   +1 more source

Atividade inseticida in vitro do óleo de sementes de nim sobre Lutzomyia longipalpis (Diptera: Psychodidae) In vitro insecticidal activity of seed neem oil on Lutzomyia longipalpis (Diptera: Psychodidae)

Revista Brasileira de Parasitologia Veterinária, 2010
Lutzomyia longipalpis é o principal vetor da Leishmaniose visceral no Brasil. O objetivo deste trabalho foi avaliar o efeito do óleo de sementes de nim (Azadirachta indica) sobre ovos, larvas e adultos do vetor.
Michelline V. Maciel, Selene M. Morais, Claudia M.L. Bevilaqua, Rafaella A. Silva, Renata S. Barros, Raimundo N. Sousa, Lindemberg C. Sousa, Lyeghyna K.A. Machado, Edy S. Brito, Manoel A. Souza-Neto   +9 more
doaj   +1 more source

Synthesis and Evaluation of the First Generation of Glycosylated Nucleoside Analogues as Potential Inhibitors of the Base J Metabolism in Kinetoplastid Parasites

Chemistry – A European Journal, Volume 32, Issue 10, 9 March 2026.
Novel analogues of the kinetoplastid‐specific DNA base J unlock a new way to target parasite epigenetic regulation. Some compounds selectively inhibit Leishmania and Trypanosoma species without harming human cells, revealing a promising route toward innovative antiparasitic therapies.
Océane Monfret, Dan Liu, Manon Louis, Sihem Rebei, Dominique Urban, Yann Bourdreux, Elisabeth Mouray, Philippe Grellier, Gilles Doisneau, Dominique Guianvarc'h   +9 more
wiley   +1 more source