Results 41 to 50 of about 9,029 (214)

Investigation of Cutaneous Leishmaniasis in the Patients Referred to the Referential Laboratories of Qom Health Center From March 2016 to February 2022

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2022
Background and Objectives: Cutaneous leishmaniasis (CL) is a common zoonotic disease that is transmitted by sandflies. This disease has become endemic in different regions of Iran.
Seyed Jafar Adnani Sadati   +3 more
doaj  

Mapping the distribution of sandflies and sandfly-associated pathogens in China

open access: yesPLOS Neglected Tropical Diseases
Background Understanding and mapping the distribution of sandflies and sandfly-associated pathogens (SAPs) is crucial for guiding the surveillance and control effort. However, their distribution and the related risk burden in China remain poorly understood.
Xue-Geng Hong   +12 more
openaire   +3 more sources

Addressing Behavioural Determinants of Cutaneous Leishmaniasis Through Community Dialogue in Kalu District, Ethiopia: A Mixed‐Methods Study

open access: yesTropical Medicine &International Health, EarlyView.
ABSTRACT Background Cutaneous leishmaniasis (CL) is a major public health challenge in Ethiopia, with 20–30,000 new cases annually. Limited awareness and misconceptions contribute to delayed care seeking, stigma, prolonged healing, and reduced uptake of preventive measures in CL‐endemic communities.
Takele Gezahegn Demie   +13 more
wiley   +1 more source

Assessment of the insecticidal activity of oral afoxolaner against Phlebotomus perniciosus in dogs

open access: yesParasite, 2019
Twelve healthy dogs were included in this laboratory efficacy study. Six dogs were randomly allocated based on body weight to an untreated control group and six to an afoxolaner (NexGard®) treated group.
Perier Nadège   +5 more
doaj   +1 more source

Natural Infection by Toscana Virus and Other Phleboviruses in Wild Sand Flies From Spain: Prevalence, Genetic Characterization and Tripartite Interactions With Leishmania infantum and Wolbachia

open access: yesZoonoses and Public Health, EarlyView.
ABSTRACT Introduction Toscana virus (TOSV) and Leishmania species are sand fly‐borne pathogens that pose a significant public health threat and an increasing risk of exposure in Europe. The objective of this study was to identify the phleboviruses circulating in an area endemic for sand fly‐borne pathogens and to estimate infection prevalence in wild ...
Andrés Torres‐Llamas   +8 more
wiley   +1 more source

sandfly samples

open access: yes, 2022
The study aimed to develop a multiplex qPCR to detect Leishmania infantum load in different sandfly sample settings using Leishmania kDNA and sandfly vacuolar ATPase (VATP) subunit C as internal control gene.
Marco Aurelio Krieger   +13 more
core   +1 more source

Peptide‐Enabled Nanoplatforms for Malaria and Leishmaniasis: From Intracellular Targeting to Translational Diagnostic Perspectives

open access: yesChemMedChem, Volume 21, Issue 18, 28 September 2026.
Peptide‐enabled nanoplatforms offer multifunctional strategies for the treatment and diagnosis of malaria and leishmaniasis. Liposomal, polymeric, and metallic nanocarriers, together with cell‐penetrating peptides and parasite‐derived mimotopes, can improve targeted drug delivery, stability, bioavailability, and intracellular localization.
Christian S. Carnero Canales   +7 more
wiley   +1 more source

Beyond the Active Site: First‐In‐Class Leishmania Infantum Trypanothione Reductase Dimerization Disruptors as Antileishmanial Leads

open access: yesChemMedChem, Volume 21, Issue 18, 28 September 2026.
This review outlines a pioneering strategy to inhibit Leishmania infantum trypanothione reductase by disrupting its dimer interface. From peptides to small‐molecule proteomimetics, multiple chemotypes achieved potent enzymatic inhibition and notable cellular antileishmanial activity, highlighting a new therapeutic paradigm.
María‐José Camarasa   +3 more
wiley   +1 more source

Species composition of Phlebotomine sandflies (Diptera: Psychodidae) in Nikshahr county, south-eastern Iran [PDF]

open access: yesJournal of Vector Borne Diseases, 2011
Background & objectives: Sandflies are reported as the vectors of different kinds of leishmaniasis to human.There are foci of the disease in Iran. The aim of this study was to determine the fauna and species compositionof sandflies to find the probable ...
H. Kassiri , E. Javadian & A.A. Hanafi-Bojd
doaj  

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