Results 201 to 210 of about 1,176,450 (305)

Conformation‐Selective Binding Domains of Intramolecular Chemically Induced Protein Dimerisation Systems

Angewandte Chemie, EarlyView.
Intramolecular chemically induced dimerisation transforms FK506‐ and cyclosporine A‐responsive protein pairs into high‐affinity pseudo‐allosteric switches. Holo‐selective binders isolated by mRNA display convert these switches into gain‐of‐signal biosensors and ultrasensitive ELISAs, enabling direct quantification of both immunosuppressants in ...
Zhenling Cui, Zhong Guo, Yi Jin Liew, Alessandro T. Caputo, Maria M. Fiorito, Cagla Ergun Ayva, Roxane Mutschler, Mayra Barrios Leguarca, Sophia Newton, Gia Nghi Lam, Robert Speight, Brett McWhinney, Yanulla Essie Georges, Carel Pretorius, Jacobus P.J. Ungerer, Kirill Alexandrov   +15 more
wiley   +2 more sources

A Comprehensive Review on Additive Manufacturing of Smart Components: Technologies, Applications, and Future Scope

Advanced Intelligent Systems, EarlyView.
How can additive manufacturing enable components that sense, adapt, heal, and power themselves? This review synthesizes recent advances in smart functionalities, manufacturing technologies, and intelligent design strategies, revealing a pathway toward fully integrated, autonomous, and multifunctional systems across diverse engineering sectors. Additive
Aiswarya Rony, P. M. Ushasree, Michael Short, Jinoop Arackal Narayanan   +3 more
wiley   +1 more source

Implantable Systems for Cardiovascular Treatment and Monitoring: Comparative Insights From Intracardiovascular and Extracardiovascular Technologies

Advanced Intelligent Systems, EarlyView.
A unifying device–cardiovascular interface framework is presented to classify implantable cardiovascular technologies as intracardiovascular blood‐contacting systems or extracardiovascular tissue‐only and blood‐handling architectures. Cross‐class comparison across shared semiquantitative criteria, including blood‐contact burden, biomimicry ...
Bergo Nicolò, Semproni Federica, Maselli Martina, Colli Andrea, Cianchetti Matteo, Ciuti Gastone, Stefanini Cesare, Menciassi Arianna   +7 more
wiley   +1 more source

Host‐Specific Interactions Between Staphylococcus aureus and Pseudomonas aeruginosa Impair Epithelial Repair in Chronic Rhinosinusitis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) is frequently associated with polymicrobial biofilms involving Staphylococcus aureus and Pseudomonas aeruginosa. Interactions between these organisms are thought to influence disease severity, but the epithelial effects of exoproteins derived from patient‐matched cocultures remain poorly defined ...
Xiaohan Sun, Mahnaz Ramezanpour, George Bouras, Emma Barry, Alkis J. Psaltis, Peter‐John Wormald, Sarah Vreugde   +6 more
wiley   +1 more source

Experimental investigation and multi-response design of FFF-printed PLA honeycomb sandwich panels for flexural performance and mass efficiency. [PDF]

PLoS One
Yelamasetti B, Agarwal A, Thotakuri M, Sushma ISP, Choden J, Kumar P N, Kumar H.   +6 more
europepmc   +1 more source

A novel double-mAb sandwich ELISA utilizing broad-spectrum neutralizing antibodies as an <i>in vitro</i> alternative to the rabies vaccine NIH potency assay. [PDF]

Front Immunol
Cai M, Wu X, Shi L, Tong J, He C, Nie J, Yang Y, Ren J, Li Y, Mao Q, Wang Y, Cao S, Huang W.   +12 more
europepmc   +1 more source

“Hands‐On” white matter anatomy: Using Air Anatomy gestures and tractography on simple brain sections to enhance teaching of white matter directions

Anatomical Sciences Education, EarlyView.
Abstract Teaching white matter (WM) anatomy to undergraduates is challenging. This is partly because WM fibers are oriented intricately and Klingler's dissection, the gold standard method used to demonstrate it, often requires time, advanced anatomical knowledge, and refined dissection skills.
Doris George Yohannan, Rohini Punja, Thomas Iype, Chandrasekharan Kesavadas, Bejoy Thomas, Kannanvilakom Govindapillai Umesan, Aswathy Maria Oommen, Usha Devi Keezhathil Bhargavi   +7 more
wiley   +1 more source

Orientation-Dependent Mechanical Response and Composite Action of Rectangular Pultruded GFRP Profiles and Integrated Sandwich Panels. [PDF]

Materials (Basel)
Han J, Fang H.
europepmc   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

Lightweight and High-Strength Sandwich Panels: Materials, Core Architectures, Manufacturing, Mechanical Performance, Multifunctionality and Future Perspectives. [PDF]

Materials (Basel)
Tang Y, Song Y, Liu Q, Wang J, Zhong Y, Chen X.   +5 more
europepmc   +1 more source