Results 1 to 10 of about 333,767 (280)

Dengue, chikungunya and Zika virus surveillance in blood donors in Brazil, 2019-2021. [PDF]

Vox Sang
Abstract Background and Objectives Arbovirus infections are a major public health concern in Brazil and an ongoing blood safety concern. Periodic outbreaks of such infections are common in the general population. This study aimed to establish the rates of dengue, chikungunya and Zika virus (DENV, CHIKV, ZIKV) RNAemia among blood donors at six public ...
Grebe E, Buccheri R, Montalvo L, Kashima S, Miranda C, Milani P, Stone M, Livezey K, Capuani L, Alencar CS, Amorim L, Loureiro P, Ribeiro M, da Costa AG, Mendrone A, Busch MP, Sabino EC, Custer B, Recipient Epidemiology and Donor Evaluation Study‐IV‐Pediatric (REDS‐IV‐P) Brazil.   +18 more
europepmc   +2 more sources

Zika virus surveillance post-epidemic in blood donors from São Paulo, Brazil 2016-2020. [PDF]

Transfus Med
Abstract Introduction Zika virus (ZIKV) is primarily transmitted through the bite of the Aedes aegypti mosquito, though transmission via blood transfusion has also been documented. During the 2015 ZIKV epidemic in Brazil, severe complications were observed in pregnant women, leading to fetal microcephaly. This study evaluated the persistence of ZIKV in
Ferreira SC, Levi JE, Nishiya AS, de Almeida-Neto C, Ferreira JE, Derriga J, Salles NA, Polato SPG, Dantas KC, Boturão-Neto E, Rocha MM, Rocha V, Mendrone-Jr A.   +12 more
europepmc   +2 more sources

Metformin Downregulates the STAT Pathway and Reduces Bone Marrow Fibrosis in Primary Myelofibrosis Patients: Final Results of the Phase II FIBROMET Trial. [PDF]

Hematol Oncol
ABSTRACT Primary myelofibrosis (PMF) is a chronic myeloproliferative neoplasm characterized by the activation of the JAK‐STAT pathway. Previous evidence showed that metformin might be a possible therapeutic option for treating JAK2‐mediated myeloproliferative neoplasms.
Melo Campos P, Pagnano KBB, Niemann FS, Mancuso RI, Della Via FI, Congrains A, Coelho-Silva JL, Tinoco ÂC, Assis-Mendonça GR, Freitas LLL, Traina F, Saad STO.   +11 more
europepmc   +2 more sources

Efficacy of Vitamin E Supplementation During Pregnancy on the Vitamin E Nutritional Status of the Mother–Child Dyad: A Systematic Review and Meta‐Analysis of Randomized Controlled Trial [PDF]

Food Sci Nutr
Summary of the systematic review and meta‐analysis evaluating the efficacy of vitamin E supplementation during pregnancy on the vitamin E nutritional status of the mother–child dyad. ABSTRACT The objective of this systematic review and meta‐analysis is to investigate the effects of vitamin E supplementation on maternal and neonatal vitamin E status ...
Carneiro B, de Araújo A, Sisinano Y, de Oliveira A, de Rezende A, da Silva Ribeiro K.   +5 more
europepmc   +2 more sources

Assessment of Leishmania exposure in blood donors from a non-endemic urban area: A study in São Paulo. [PDF]

Vox Sang
Abstract Background and Objectives According to the World Health Organization, more than 1 billion people are at risk of leishmaniasis in over 89 countries. Environmental changes such as deforestation, urban expansion and climate change facilitate the spread of sand fly vectors and reservoirs, increasing disease transmission.
de Lima IS, Ferreira SC, Nishiya AS, Kesper N, Ferreira JE, de Castro Gomes CM, Derriga J, Dantas KC, Polato SPG, Salles NA, Lindoso JAL, Fanciani T, de Almeida-Neto C, Rocha V, Mendrone A.   +14 more
europepmc   +2 more sources

Selection and Characterisation of Minor Histocompatibility Antigen-Specific Regulatory T Cells in Fully HLA-Matched Setting for GVHD Therapy. [PDF]

Eur J Immunol
We optimised a protocol for mHA‐specific Treg (mTreg) selection in an HLA‐matched context while defining its phenotype, transcriptional state and function. mTreg were highly activated and exerted specific, HLA class II‐, contact‐dependent suppression. This protocol can be explored as a highly personalised antigen‐specific Treg‐based therapy in future ...
Pacini CP, Azevedo RI, Ramalhete L, Lainé HAJ, Soares MVD, Lacerda JF.   +5 more
europepmc   +2 more sources

ANÁLISE DA QUALIDADE DOS CONCENTRADOS DE HEMÁCIAS PRODUZIDOS POR SISTEMA AUTOMATIZADO

Hematology, Transfusion and Cell Therapy, 2023
Introdução: As etapas do ciclo do sangue necessitam de uma avaliação rigorosa para assegurar a qualidade dos hemocomponentes produzidos a serem transfundidos.
KCS Oliveira, WM Silva, VGM Costa, ECP Assis, MR Barbosa, PAB Souza, LHR Gabriel, RF Cardoso, LSR Pires   +8 more
doaj   +1 more source

ESTRATÉGIAS DE CONTROLE DE RISCO BACTERIANO RELACIONADAS A DISPONIBILIDADE DE PLAQUETAS PARA TRANSFUSÃO

Hematology, Transfusion and Cell Therapy, 2023
Introdução: A literatura médica relata que a contaminação bacteriana em um hemocomponente pode variar de 0,04% a 2%, dependendo do tipo do componente sanguíneo.
VGM Costa, KCS Oliveira, MR Barbosa, ECP Assis, LSR Pires, RF Cardoso, LHR Gabriel   +6 more
doaj   +1 more source

AVALIAÇÃO DO TESTE DO ÁCIDO NUCLÉICO (NAT) E QUIMIOLUMINESCÊNCIA NA TRIAGEM SOROLÓGICA EM DOADORES DE SANGUE DO VITA HEMOTERAPIA DA BAHIA

Hematology, Transfusion and Cell Therapy, 2023
Introdução: Após anos de debates, o Teste de detecção de Ácidos Nucleicos (NAT) para HIV e HCV na triagem de sangue foi implementado de forma obrigatória no Brasil em 2013, e HBV, em 2016 Essa técnica apresenta alta sensibilidade para detecção da ...
S Falcão, R Silva, R Coutos, A Souza, E Menezes, L Santos, A Soares, A Pires   +7 more
doaj   +1 more source

PREVALÊNCIA DA PRESENÇA DE HBS EM DOADORES DE SANGUE DO VITA HEMOTERAPIA DA BAHIA

Hematology, Transfusion and Cell Therapy, 2023
Introdução: O traço falciforme é caracterizado pela presença de hemoglobina S (HbS) em heterozigose. Estima-se que no mundo existam cerca de 30 milhões de portadores do traço falciforme e, devido ao alto grau de miscigenação que transcorre no Brasil a ...
S Falcão, R Silva, R Coutos, A Souza, E Menezes, L Santos, A Soares, A Pires   +7 more
doaj   +1 more source