Results 21 to 30 of about 161,329 (200)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Le boisement et la conservation de la forêt de Rambouillet du XVIII^e siècle à nos jours

Revue Forestière Française
La forêt tient un rôle central dans le paradigme de la conservation de la nature né en Europe entre le XVIIe et le XIXe siècle. Le boisement y est considéré comme un bon état de santé de la sylve, espace peuplé d’arbres à vocation de production.
Raphaël Devred
doaj   +1 more source

Collaborations, évitements et conflits entre disciplines autour d’un terrain partagé [PDF]

Natures Sciences Sociétés, 2016
Cet article interroge les collaborations, les conflits et les évitements qui se nouent entre disciplines autour d’un terrain d’étude partagé. À l’aide de la notion d’espace-frontière, j’analyserai l’exemple de la forêt périparisienne ...
Massart Clémence
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Les jeunes enfants à Bruxelles : d’une logique institutionnelle à une vision systémique

Brussels Studies, 2015
In the Belgian federal system, matters related to persons are under the remit of the Community and not of the Region. But although matters such as education and culture are managed in a French- or Dutch-language framework, they are major challenges for ...
Perrine Humblet, Gaëlle Amerijckx, Stéphane Aujean, Murielle Deguerry, Michel Vandenbroeck, Benjamin Wayens   +5 more
doaj   +1 more source

Relations entre santé et espaces verts et bleus : une synthèse de la recherche empirique, 2003-2014 [PDF]

Natures Sciences Sociétés, 2015
Cet article examine treize revues de synthèse de la recherche scientifique et des publications officielles qui traitent des effets positifs de l’exposition à un environnement naturel sur les dimensions psychique, physique et sociale ...
Zufferey Joris
doaj   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon, Hugues Chabriat, Dominique Hervé, Stéphanie Guey, Sophie Tezenas Du Montcel, Juliette Ortholand   +5 more
wiley   +1 more source

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau, Marie Bruguet, Irina Viakhireva‐Dovganyuk, François‐Mathias Merrien, Denis Marechal, Aurore Jourdain, Philippe Goas, Jordan Coris, Julien Asselineau, Maëlys Consigny, Gérald Le Gac, Serge Timsit   +11 more
wiley   +1 more source

Déterminants des choix de plantation d’arbres dans les jardins domestiques en contexte de colonisation par la processionnaire du pin (Thaumetopoea pityocampa)

Natures Sciences Sociétés
Avec les changements globaux, certaines espèces d’insectes dont la prolifération est néfaste pour la santé humaine, comme la processionnaire du pin (Thaumetopoea pityocampa), colonisent de nouveaux territoires auparavant inadaptés à leur développement ...
Mohamed Anaïs, Di Pietro Francesca, Rousselet Jérôme   +2 more
doaj   +1 more source