Results 71 to 80 of about 1,430,831 (294)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

LITOPTERNA (MAMMALIA) FROM THE SANTA CRUZ FORMATION (EARLY–MIDDLE MIOCENE) AT THE RÍO SANTA CRUZ, SOUTHERN ARGENTINA

Publicación Electrónica de la Asociación Paleontológica Argentina, 2019
Litopterna from fossiliferous exposures of the Santa Cruz Formation (Early–Middle Miocene) along the Río Santa Cruz, Patagonia Argentina, are analyzed and described.
Gabriela Ines Schmidt, Santiago Hernández Del Pino, Nahuel Antú Muñoz, Mercedes Fernández   +3 more
doaj  

PERISTIWA SANTA CRUZ 12 NOVEMBER 1991: DINAMIKA SEJARAH TIMOR TIMUR PASCA INTEGRASI KE DALAM WILAYAH NEGARA KESATUAN REPUBLIK INDONESIA [PDF]

, 2016
Skripsi yang berjudul “Peristiwa Santa Cruz 12 November 1991: Dinamika Sejarah Timor Timur Pasca Integrasi ke Dalam Wilayah Negara Kesatuan Republik Indonesia” ini mengangkat permasalahan peristiwa Santa Cruz 12 November 1991 sebagai suatu peristiwa yang
Iskandar, Irfan
core  

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Calliini (Coleoptera, Cerambycidae, Lamiinae): descrições, homonímia, novo registro e chave para as espécies de Graminea Thomson, 1864

Papéis Avulsos de Zoologia, 2006
Calliini (Coleoptera, Cerambycidae, Lamiinae): descrições, homonímia, novo registro e chave para as espécies de Graminea Thomson, 1864. Espécies novas descritas: Paracallia giesberti sp. nov. da Bolívia (Cochabamba), Colombicallia albofasciata sp. nov. e
Ubirajara R. Martins, Maria Helena M. Galileo   +1 more
doaj   +1 more source

Spatial Regression Analysis of Deforestation in Santa Cruz, Bolivia [PDF]

, 2002
This paper applies a spatial economic regression model to analyze the relation between deforestation in the period from 1989 to 1994 and access to roads and markets, ecological conditions, land tenure, and zoning policies in Santa Cruz, Bolivia. The data
Kaimowitz, David, Mendez, P., Puntodewo, Atie, Vanclay, Jerome K.   +3 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

O arquivo pessoal de José Petronilo de Santa Cruz: o livreiro-editor da Livraria Duas Cidades

Revista do Instituto de Estudos Brasileiros, 2020
RESUMO Este artigo investiga o arquivo pessoal de José Petronilo de Santa Cruz e abarca aspectos (auto)biográficos e da cultura escrita relacionada à Livraria Duas Cidades, fundada e dirigida por Santa Cruz na cidade de São Paulo.
Hugo Quinta, Wilton Carlos Lima da Silva
doaj   +1 more source

CLEO Contributions to Tau Physics [PDF]

, 2002
We review many of the contributions of the CLEO experiment to tau physics. Topics discussed are: branching fractions for major decay modes and tests of lepton universality; rare decays; forbidden decays; Michel parameters and spin physics; hadronic sub ...
Ahmed, Alam, Alan J. Weinstein, Albrecht, Alexander, Ammar, Ammar, Anastassov, Anastassov, Anderson, Anderson, Anderson, Artuso, Artuso, Asner, Asner, Athanas, Avery, Bai, Balest, Balest, Balest, Barnett, Barnett, Bartelt, Bartelt, Battle, Bean, Bergfeld, Bergfeld, Bishai, Bliss, Bonvicini, Bonvicini, Bortoletto, Browder, Cinabro, Cinabro, Coan, Coan, Coan, Crawford, Davier, Duboscq, Duboscq, Edwards, Edwards, Edwards, Gibaut, Godang, Jadach, Jadach, Jadach, Jadach, Jadach, Jadach, Jadach, Kubota, Procario, Richichi, Smith, Smith, Suzuki   +62 more
core   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source