Results 51 to 60 of about 575,667 (310)
Publicación Electrónica de la Asociación Paleontológica Argentina, 2019 The Thematic Volume “Early-Middle Miocene Paleontology in the Río Santa Cruz, Southern Patagonia, Argentina. 130 years since Ameghino, 1887” deals with the geology, chronology and the fossils of the Santa Cruz Formation in the Río Santa Cruz recovered in
Juan C. Fernicola +3 more
doaj
Novas espécies de Onciderini (Coleoptera, Cerambycidae, Lamiinae) da Bolívia
Papéis Avulsos de Zoologia, 2008 Novas espécies descritas da Bolívia, Santa Cruz: Trachysomus apipunga sp. nov., Hesychotypa aotinga sp. nov., Cacostola apyraiuba sp. nov. and Glypthaga nearnsi sp. nov.New species of Onciderini (Coleoptera, Cerambycidae, Lamiinae) from Bolivia.
Ubirajara R. Martins +1 more
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Gestão da produção intelectual pelo método participativo: o caso da Universidade de Santa Cruz do Sul [PDF]
, 2004 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia de Produção.Este trabalho propõe um modelo de gestão da produção e da disseminação do conhecimento para as universidades brasileiras: o
Cruz, Wilson Kniphoff da
core
Papéis Avulsos de Zoologia, 2006 Calliini (Coleoptera, Cerambycidae, Lamiinae): descrições, homonímia, novo registro e chave para as espécies de Graminea Thomson, 1864. Espécies novas descritas: Paracallia giesberti sp. nov. da Bolívia (Cochabamba), Colombicallia albofasciata sp. nov. e
Ubirajara R. Martins +1 more
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Caracterización del circuito comercial del ganado bovino en el departamento de Rio Chico, Santa Cruz [PDF]
, 2015 La cadena de carne bovina, como otras del sector agroalimentaria, es caracterizada por la diversidad de actores que participan en ella. Con la finalidad de reunir, analizar y ofrecer información para caracterizar el circuito comercial relacionado al ...
Seeber, German Alejo +1 more
core
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Publicación Electrónica de la Asociación Paleontológica Argentina, 2019 Litopterna from fossiliferous exposures of the Santa Cruz Formation (Early–Middle Miocene) along the Río Santa Cruz, Patagonia Argentina, are analyzed and described.
Gabriela Ines Schmidt +3 more
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source