Results 221 to 230 of about 153,433 (298)

Self‐Knowledge and the Capacity to Judge

open access: yesEuropean Journal of Philosophy, EarlyView.
Abstract Several philosophers have sought to explain certain features of self‐knowledge our beliefs on the basis of the relation which holds between them and our judgments. Typically, these philosophers presuppose that there is just a single relation between these, for instance the relation of identity.
Matthew Parrott
wiley   +1 more source

The Master's Problem: Revisiting Hegel's Critique of Social Domination

open access: yesEuropean Journal of Philosophy, EarlyView.
Abstract This paper argues for a reinterpretation of Hegel's internal critique of the master in his famous ‘Master–Slave Dialectic.’ Hegel argues that, in addition to the evident injustice suffered by the enslaved, the arrangement also undermines the master's own purposes.
Stephen Cunniff
wiley   +1 more source

Digital platform strategies from an incumbent perspective: An exploration of contextual factors and connectors

open access: yesEuropean Management Review, EarlyView.
ABSTRACT Multi‐sided platform (MSP) models have become more relevant for incumbent companies, requiring them to develop MSP engagement strategies. This study sheds light on the complex process incumbents undergo in developing platform strategies. Adopting an inductive research design, we conducted interviews with 37 decision‐makers across 35 incumbent ...
Lukas Zechel, Vivek K. Velamuri
wiley   +1 more source

Flow‐controlled expiration improves gas exchange in anaesthetised horses undergoing orthopaedic surgery

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Flow‐controlled expiration (FLEX) has been shown to significantly enhance oxygenation in horses under laboratory conditions. Objective This study aims to corroborate these findings by evaluating the effects of FLEX on gas exchange in a randomised clinical trial involving a large population of clinical horses undergoing orthopaedic ...
Klaus Hopster   +5 more
wiley   +1 more source

Extracellular matrix and proteolysis: mechanisms driving irreversible changes and shaping cell behavior

open access: yesThe FEBS Journal, EarlyView.
Irreversible ECM proteolysis by remodeling enzymes shapes development, homeostasis, and disease. ECM‐degrading proteases display cell specificity and are governed by shared mechanisms, exhibiting functional redundancy in generating matrikines, growth factors, and cytokines.
Inna Solomonov, Orit Kollet, Irit Sagi
wiley   +1 more source

Regulation of PHOX2B gene expression by the long non‐coding natural antisense RNA PHOX2B‐AS1

open access: yesThe FEBS Journal, EarlyView.
PHOX2B is a transcription factor essential for autonomic nervous system development. We identify and characterize PHOX2B‐AS1, a human long non‐coding antisense transcript at the PHOX2B locus, along with its murine counterpart. Our findings reveal bidirectional transcription and reciprocal regulation: PHOX2B activates PHOX2B‐AS1, whereas PHOX2B‐AS1 ...
Simona Di Lascio   +12 more
wiley   +1 more source

Arsenite methyltransferase 3 is required for mitochondrial function and hepatic lipid metabolism

open access: yesThe FEBS Journal, EarlyView.
AS3MT is a protein that helps the body process arsenic, a naturally occurring toxin found in water and soil. We discovered it also helps cells make and use energy properly. Without AS3MT, cells' mitochondria do not work well, leading to fatty liver and reduced activity. Increasing AS3MT in liver cells restores energy and protects against arsenic damage,
Patrice Delaney   +10 more
wiley   +1 more source

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