Results 91 to 100 of about 3,791 (140)

Colonic Malakoplakia With an Adenomatous Appearance on Magnification Endoscopy: A Case Report

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Malakoplakia is a rare chronic granulomatous disease associated with impaired macrophage phagocytosis of bacteria. Because colonic malakoplakia presents with varied endoscopic appearances, its characteristic features have not been clearly defined, and differentiation from colorectal neoplasms during endoscopy may be difficult. We report a case
Shima Sono, Kiichiro Kaji, Miyabi Miura, Hideo Takayama, Kohei Yasuda, Kuniaki Arai, Kenichi Harada, Shuichi Terasaki   +7 more
wiley   +1 more source

Sarcoidosis: patient treatment priorities

ERJ Open Research, 2018
Robert P. Baughman, Rita Barriuso, Kelli Beyer, Jeanette Boyd, Johann Hochreiter, Chris Knoet, Filippo Martone, Bernd Quadder, Jack Richardson, Ginger Spitzer, Dominique Valeyre, Gianluca Ziosi   +11 more
doaj   +1 more source

Targeting Inflammatory and Oxidative Pathways in Idiopathic Pulmonary Fibrosis: Synergistic Effects of Quercetin and Pirfenidone in Modulating Nrf2/PPAR‐γ and TLR‐4/NF‐κB Pathways

Pharmacology Research &Perspectives, Volume 14, Issue 2, April 2026.
Pirfenidone (Pirf) and Quercetin (Quer) both reduced inflammation, oxidative stress, and fibrosis in a bleomycin‐induced pulmonary fibrosis model, with Quer showing a stronger effect than Pirf. The combination of Pirf and Quer provided enhanced anti‐fibrotic and anti‐inflammatory benefits, suggesting potential for improved therapeutic strategies in ...
Hanaa Wanas, Amira Karam Khalifa, Hossein M. Elbadawy, Amany E. Hamoud, Mohannad A. Almikhlafi, Emad Ali Albadawi, Hadel Mahroos Alghabban, Wejdan Hussain Owaydhah, Amr M. Galal   +8 more
wiley   +1 more source

Sarcoidosis and Polymethyl Methacrylate (PMMA) Granulomas following COVID-19 Vaccination (ChAdOx1): Successful Treatment with Tofacitinib

Indian Journal of Dermatology
Sarcoidosis and complications related to fillers have been reported following the COVID-19 vaccination. Additionally, cutaneous sarcoidosis has been observed around polymethyl methacrylate (PMMA) injection sites.
Mayra Ianhez, Hélio A Miot, Lívia VN Caetano, Henrique Moura de Paula, Giselle GS Freire, Pedro PTS Torres   +5 more
doaj   +1 more source

Epidemiology and Genetics of Rheumatic Diseases Suggest a Constant Rate of DNA Damage as Underlying Cause

Immunology, Volume 177, Issue 4, Page 736-748, April 2026.
A constant rate of DNA damage that is not perfectly repaired will cause a constant rate of DNA mutations. The chance of mutation will increase if DNA is prone to damage, such as occurs in somatic hypermutation (SHM) hotspots and GC‐rich DNA. Thus, if one mutation‐prone DNA site drives disease, the age of onset of disease and degree of penetrance should
Piet C. de Groen
wiley   +1 more source

Rare and common manifestation of musculoskeletal and sinonasal sarcoidosis: A case report

Radiology Case Reports
Sarcoidosis is a systemic granulomatous disease that can affect multiple organ systems. Although many sarcoidosis patients are asymptomatic, the variable clinical progression of symptomatic patients and the nonspecific presentation make diagnosis ...
Kihyun Kwon, MD, Eric Taub, MD, Brandon Dang, MD, Joseph Dobtsis, MD   +3 more
doaj   +1 more source

Transition From Juvenile Dermatomyositis to Spondyloarthritis: A Novel Overlapping Inflammatory Phenotype

ACR Open Rheumatology, Volume 8, Issue 3, March 2026.
Objective Juvenile dermatomyositis (JDM) is a rare childhood inflammatory myopathy, whereas spondyloarthritis (SpA) is an inflammatory arthropathy characterized by enthesitis and peripheral or axial involvement. We describe a series of patients diagnosed with JDM in childhood who later fulfilled classification criteria for SpA, a sequential phenotype ...
Austen Grooms, Ioannis Karageorgiou, Kerry Mychaliska, James Birmingham   +3 more
wiley   +1 more source

Reliability and Construct Validity of the Physician's Global Assessment of Lung Disease in Systemic Juvenile Idiopathic Arthritis–Associated Lung Disease

ACR Open Rheumatology, Volume 8, Issue 3, March 2026.
Objective The physician global assessment of lung disease (PGALD) is a recently proposed disease activity measure for patients with systemic juvenile idiopathic arthritis–associated lung disease (SJIA‐LD). This study evaluates the reliability and construct validity of the PGALD.
Eileen Rife, Guihua Zhai, Mekibib Altaye, Jennifer Andringa, Hermine I. Brunner, Scott Canna, Lauren A. Henderson, Yukiko Kimura, Scott M. Lieberman, Mona Riskalla, Christopher Towe, Tiphanie Vogel, Holly Wobma, Grant Schulert, for the PGALD Validation Consortium Investigators, Rabheh Abdul Aziz, Sheila Angeles‐Han, Kevin Baszis, Edward Behrens, Hermine I. Brunner, Gregory Burg, Scott Canna, Alicia Casey, Matthew Clark, Dominic Co, Kathleen Collins, Randy Cron, Marietta DeGuzman, Fatma Dedeoglu, Robin Deterding, Barbara Eberhard, Deanna Green, Timothy Hahn, Daniel M. Hinds, Patricia Hobday, Sandy Hong, Aimee Hersh, Jennifer Huggins, Yukiko Kimura, Susan Kim, Marisa Klein‐Gitelman, Daniel Lovell, Patricia Lu, Melissa Mannion, Jessica Neely, Michael O'Connor, Karen Onel, Amir Orandi, Andrea Ramirez, Adam Reinhard, Mona Riskalla, Steven Rose, Kristen Ruff, Laisa Santiago, Vivian Saper, Susan Shenoi, Manuel Silva‐Carmona, Emily Smitherman, David R. Spielberg, Jade Tam‐Williams, Christopher Towe, Tracy Ting, Fernando Urrego, Timothy Vece, Tiphanie Vogel, Jennifer Weiss, Holly Wobma, Lauren A. Henderson, Scott M. Lieberman, Julian Vyas, Lisa Young   +70 more
wiley   +1 more source

Delays in Referral to Multidisciplinary Care for Black Individuals With SarcoidosisTake-Home Points

CHEST Pulmonary
Background: Sarcoidosis is a complex granulomatous disease that benefits from multidisciplinary subspecialty expertise. Inequitable access to care contributes to racial disparities in many diseases; however, to our knowledge, no studies have examined ...
Kristen R. Mathias, MD, Ofure Akhiwu, MD, Ali M. Mustafa, MD, Kevin J. Psoter, PhD, Edward S. Chen, MD, Nisha A. Gilotra, MD, Nancy W. Lin, MD, John Odackal, MD, Catherine A. Bonham, MD, Michelle Sharp, MD   +9 more
doaj   +1 more source

Advances in Bioprinting to Model Immune‐Mediated Skin Diseases

Advanced Healthcare Materials, Volume 15, Issue 9, 6 March 2026.
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández, Marica Markovic, Julia Fernández‐Pérez, Georg Stary, Aleksandr Ovsianikov   +4 more
wiley   +1 more source