Results 71 to 80 of about 104,670 (250)

Long-Term Corticosteroid-Sparing Immunosuppression for Cardiac Sarcoidosis. [PDF]

, 2019
Background Long-term corticosteroid therapy is the standard of care for treatment of cardiac sarcoidosis (CS). The efficacy of long-term corticosteroid-sparing immunosuppression in CS is unknown.
Benn, Bryan S, De Marco, Teresa, Gerstenfeld, Edward P, Hsia, Henry H, Janmohamed, Munir, Klein, Liviu, Koth, Laura L, Lee, Byron K, Moss, Joshua D, Murray, Tyler O, Pampaloni, Miguel H, Parwani, Purvi, Petek, Bradley J, Rosenthal, David G, Scheinman, Melvin M, Selby, Van, Vedantham, Vasanth, Zikherman, Julie   +17 more
core  

PEPITEM Regulates the Synovial Microenvironment During Immune‐Mediated Inflammatory Arthritis to Limit Disease

Arthritis &Rheumatology, EarlyView.
Objective Here we investigate the status of the adiponectin–PEPITEM pathway in early, treatment naive rheumatoid arthritis (RA) and psoriatic arthritis (PsA) and the therapeutic efficacy of PEPITEM administration in preclinical models. Methods Peripheral blood was isolated from patients with clinical suspect arthralgia and suspected inflammatory ...
Mussarat Wahid, Samuel Kemble, Oladimeji Abudu, Anella Saviano, Christopher Mahony, Jonathan W. Lewis, Thomas A. Nicholson, Anna Schettino, Noemi Marigliano, Kathryn Frost, Jenefa Begum, Alyssa M. Urbanowski, Marion Limo, Rakesh Jha, Sandra Martinez Jarquin, Laleh Pezhman, Abbie E. A. Degan, Amy E. Anderson, Charlotte G. Smith, Armaiti Batki, Holly Adams, Francesco Caso, Raffaele Scarpa, Iain McInnes, Stefan Siebert, Arthur G. Pratt, Andrew Filer, Karim Raza, Adam P. Croft, Myriam Chimen, Felicity de Cogan, G. Ed Rainger, Asif J. Iqbal, Francesco Maione, Helen M. McGettrick   +34 more
wiley   +1 more source

Evaluation of clinical and laboratory characteristics of patients with cutaneous sarcoidosis: A single-center retrospective cohort study

Frontiers in Medicine, 2022
BackgroundCutaneous sarcoidosis is a relatively rare disease whose clinical manifestations include red-brown macules, plaques, papules and subcutaneous nodules. The skin changes may also be restricted to pre-existing scars.
Katharina Boch, Ewan A. Langan, Ewan A. Langan, Detlef Zillikens, Ralf J. Ludwig, Khalaf Kridin, Khalaf Kridin   +6 more
doaj   +1 more source

The price of tumor control: an analysis of rare side effects of anti-CTLA-4 therapy in metastatic melanoma from the ipilimumab network [PDF]

, 2013
Background: Ipilimumab, a cytotoxic T-lymphocyte antigen-4 (CTLA-4) blocking antibody, has been approved for the treatment of metastatic melanoma and induces adverse events (AE) in up to 64% of patients.
A Bashey, A Eckert, A Ribas, AA Sarnaik, Armin Justich, AV Maker, AV Maker, Axel Hauschild, Beatrice Schuler-Thurner, C Robert, Carmen Loquai, Carola Berking, Caroline J. Voskens, Caroline Robert, Christina Klein, Christine Mateus, Claus Garbe, Clemens L. Bockmeyer, Daniela Göppner, Dirk Schadendorf, F Bompaire, F Fadel, F Torino, FS Hodi, FS Hodi, G Berthod, G Borodic, G Graziani, G Graziani, G Hunter, G Hunter, Gerold Schuler, Gheorghe Hundorfean, GQ Phan, GY Ku, H Gogas, H Tlaskalova-Hogenova, H. Peter Soyer, HB Wang, Imke Satzger, J Delyon, JA Blansfield, JD Wolchok, JD Wolchok, Jens Ulrich, JJ Nordlund, JM Kirkwood, JS Weber, JS Weber, JS Weber, Julia Vaubel, K Harmankaya, K Sanderson, Katharina C. Kaehler, KD Chmiel, KE Beck, L Min, LM Heinzerling, Lucie M. Heinzerling, Marc Schlaeppi, Michael Fluck, OP Hamnvik, P Attia, PA Prieto, Patrik Weder, Peter Mohr, Ralf Gutzmer, Reinhard Dummer, RH Friedline, Roger von Moos, Rüdiger Hein, S Bhatia, S Wilgenhof, S Wilgenhof, S Wilgenhof, SG Downey, Simone M. Goldinger, SM Liu, Stephan Grabbe, Sylvie Paetzold, T Bakacs, T Matsui, Tabea Wilhelm, Tanja Bergmann, Thomas Eigentler, Ullrich Keller, Uwe Trefzer, WB Breunis, WV Vogel   +88 more
core   +4 more sources

Hyperparathyroidism Presenting as Acute Pancreatitis: Case Report of Mortality [PDF]

, 2020
Background: Acute pancreatitis may be caused by a myriad of factors, hypercalcemia secondary to hyperparathyroidism, albeit is a rare cause of acute pancreatitis but not unheard of.
Gillani, M. M. (Muhammad), Raza, V. F. (Vishal)   +1 more
core   +1 more source

Intraosseous sarcoidosis imitating peri‐implantitis: A case study

Clinical Advances in Periodontics, EarlyView.
Abstract Background Sarcoidosis is a multisystem granulomatous disorder of unknown cause, typically affecting the lungs and lymph nodes, but it can also involve the eyes, skin, heart, bones, and other organs. The exact cause is unclear, but genetic factors and environmental triggers like infections, chemicals, or dust may play a role.
Magdalena Orlowska, David S. Gottlieb, Kenneth S. Kornman   +2 more
wiley   +1 more source

Gut microbiota‐related modulation of immune mechanisms in post‐infarction remodelling and heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler, Friederike Zimmermann, Bettina Heidecker, Ulf Landmesser, Arash Haghikia   +4 more
wiley   +1 more source

Ocular sarcoidosis, to screen or not to screen?

Frontiers in Medicine
Ocular sarcoidosis most commonly presents with symptoms and is first diagnosed before systemic sarcoidosis in at least half of the patients with sarcoidosis.
Sanna Leinonen, Sanna Leinonen
doaj   +1 more source

Immunoreactivity to metal and silica associates with sarcoidosis in Dutch patients

Respiratory Research, 2020
Background Involvement of metals or silica in the pathogenesis of sarcoidosis has been suggested by several case reports and specific epidemiological studies.
E. Beijer, B. Meek, X. Bossuyt, S. Peters, R. C. H. Vermeulen, H. Kromhout, M. Veltkamp   +6 more
doaj   +1 more source

Prognostic role of high‐sensitivity cardiac troponin T in patients with cardiac sarcoidosis: insights from ILLUMINATE‐CS

ESC Heart Failure, Volume 12, Issue 2, Page 869-878, April 2025.
Abstract Aims The prognostic role of high‐sensitivity cardiac troponin T (hs‐cTnT) as a biomarker in patients with cardiac sarcoidosis (CS) has yet to be fully determined, especially when compared with B‐type natriuretic peptide (BNP). Methods and Results In this post‐hoc analysis of the ILLUMINATE‐CS (ILLUstration of the Management and prognosIs of ...
Yuichi Baba, Toru Kubo, Takeru Nabeta, Yuya Matsue, Takeshi Kitai, Yoshihisa Naruse, Tatsunori Taniguchi, Hidekazu Tanaka, Takahiro Okumura, Kenji Yoshioka, Hiroaki Kitaoka   +10 more
wiley   +1 more source