Results 61 to 70 of about 60,365 (226)

TREM-1 and TREM-2 Expression on CD14+ Cells in Bronchoalveolar Lavage Fluid in Pulmonary Sarcoidosis and Hypersensitivity Pneumonitis in the Context of T Cell Immune Response

Mediators of Inflammation, 2020
Background. Sarcoidosis and hypersensitivity pneumonitis (HP) are immunologically mediated processes caused by hypersensitivity reaction accompanied by similar features including lymphocytic alveolitis and granuloma formation. Recent studies describe the
M. Suchankova, J. Urban, M. Ganovska, E. Tibenska, K. Szaboova, E. Tedlova, F. Sandor, I. Majer, M. Bobovcak, I. Jonner, B. Konig, M. Bucova   +11 more
doaj   +1 more source

Tolerability of Adjuvant Nivolumab in Esophageal or Gastroesophageal Junction Cancer: A Real‐World Study

International Journal of Cancer, EarlyView.
ABSTRACT Adjuvant nivolumab is approved for esophageal or gastroesophageal junction cancer after neoadjuvant chemoradiotherapy and resection. In the CheckMate‐577 trial, Grade 3–5 nivolumab‐related adverse events (AEs) occurred in 5% of patients, with early discontinuation due to toxicity in 9%. However, real‐world data on immunotherapy‐related adverse
Michelle Koops van ’t Jagt, Anniek Strijdhorst, Tamara Jessica Huizer, Esther Albertien Kleibeuker, Sarah Derks, Bianca Mostert, Hanneke van Laarhoven, Jacco Juri de Haan   +7 more
wiley   +1 more source

A hepatic enigma: Pediatric presentation of primary biliary cholangitis

JPGN Reports, EarlyView.
Abstract Primary biliary cholangitis (PBC) is a chronic autoimmune condition characterized by destruction of intrahepatic bile ducts, leading to fibrosis and cirrhosis of the liver. It is an extremely rare pediatric disease with very few pediatric cases reported to date. Here, we report the case of a 14‐year‐old female who presented with elevated liver
Sindhura Kasturi, Rachel Schenker, Nick Shillingford, George Yanni   +3 more
wiley   +1 more source

Innovating care for people with sarcoidosis using a machine learning-driven approach

Respiratory Research
Introduction Understanding patients’ everyday experience is essential to improve patient centered care in sarcoidosis. So far, patient perspectives are based on survey- and qualitative research. Aim We aimed to assess patient-driven perspectives on their
Vivienne Kahlmann, Astrid Dunweg, Heleen Kicken, Nick Jelicic, Johanna M. Hendriks, Richard Goossens, Marlies S. Wijsenbeek, Jiwon Jung   +7 more
doaj   +1 more source

Autoimmune pulmonary alveolar proteinosis in a patient with sarcoidosis

Clinical Case Reports, 2019
Key Clinical Message Steroids used to treat sarcoidosis may induce aPAP. The cooccurrence of sarcoidosis and autoimmune pulmonary alveolar proteinosis (aPAP) is rare.
Yuko Tanaka, Toshihiro Shirai, Kazuhiro Asada, Aya Muramatsu, Mineo Katsumata, Takafumi Suda   +5 more
doaj   +1 more source

Validity and Responsiveness of Chronic Rhinosinusitis Control Test Subdomains

The Laryngoscope, EarlyView.
The chronic rhinosinusitis control test (CRCT) is a psychometrically validated 8‐item patient‐reported outcome measure developed based on international consensus that measures, quantifies and classifies CRS control. The CRCT has two subdomains: a sinonasal subdomain and an impairment subdomain that measure distinct but complementary constructs related ...
Ahmad R. Sedaghat, Katie M. Phillips
wiley   +1 more source

Ocular sarcoidosis, to screen or not to screen?

Frontiers in Medicine
Ocular sarcoidosis most commonly presents with symptoms and is first diagnosed before systemic sarcoidosis in at least half of the patients with sarcoidosis.
Sanna Leinonen, Sanna Leinonen
doaj   +1 more source

Hepatic Sarcoidosis: Natural History and Management Implications

Frontiers in Medicine, 2019
Introduction: Hepatic granulomas are common in patients with sarcoidosis, but clinically significant liver disease is uncommon and poorly studied. We aimed to characterize the frequency and clinical course of hepatic sarcoidosis in an ethnically diverse ...
Mai Sedki, Nicholas Fonseca, Priscila Santiago, Liege Diaz, Monica Garcia-Buitrago, Mehdi Mirsaeidi, Cynthia Levy   +6 more
doaj   +1 more source

Factors Associated With Bilateral Involvement in Non‐Infectious Labyrinthitis: A Case–Control Study

The Laryngoscope, EarlyView.
Non‐infectious labyrinthitis may progress from unilateral to bilateral inner‐ear involvement, resulting in greater functional impairment. In this retrospective case–control study of 50 patients, younger age, female sex, and the presence of systemic disease were associated with bilateral involvement. These exploratory findings may help identify patients
Douglas Henderson, Blanca Amador Borrero, Aurélien Cadix, Karine Champion, Damien Sene, Philippe Herman, Charlotte Hautefort, Alain Londero, Michael Eliezer, Cassandre Djian   +9 more
wiley   +1 more source

Outdated Frameworks, Missed Opportunities: A Call for Establishing Classification Criteria for Patients with Sarcoidosis

Rheumatology and Therapy
Progress in sarcoidosis research is hampered by inconsistent definitions and study entry criteria that rely on variable local practice patterns and widely differing expert opinions.
Nadera J. Sweiss, Arnaud Dominati, Mary McGowan, Tricha Shivas, Alexandra Ladouceur, Israel Rubinstein, Murray Baron   +6 more
doaj   +1 more source