Results 91 to 100 of about 57,209 (210)

Legumain Restrains Granuloma Formation by Inhibiting mTORC1/STAT1‐Mediated M1 Macrophage Polarization in Sarcoidosis

open access: yesAdvanced Science, Volume 13, Issue 33, 15 June 2026.
Legumain (LGMN) is upregulated in macrophages during sarcoid‑like granuloma formation. Macrophage‑derived LGMN binds to integrin αvβ3 and suppresses mTORC1/STAT1 signaling to restrain M1 macrophage polarization. Intratracheal delivery of lipid nanoparticles carrying Lgmn plasmid DNA (pDNA) elevates LGMN expression and effectively attenuates pulmonary ...
Mengyuan Liu   +12 more
wiley   +1 more source

Sarcoidosis: patient treatment priorities

open access: yesERJ Open Research, 2018
Robert P. Baughman   +11 more
doaj   +1 more source

Intraosseous sarcoidosis imitating peri‐implantitis: A case study

open access: yesClinical Advances in Periodontics, Volume 16, Issue 2, Page 251-259, June 2026.
Abstract Background Sarcoidosis is a multisystem granulomatous disorder of unknown cause, typically affecting the lungs and lymph nodes, but it can also involve the eyes, skin, heart, bones, and other organs. The exact cause is unclear, but genetic factors and environmental triggers like infections, chemicals, or dust may play a role.
Magdalena Orlowska   +2 more
wiley   +1 more source

ERDHEIM‐Chester Disease: Two Fatal Cases With Unusual Presentations

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
Fluorodeoxyglucose positron emission tomography‐computed tomography (FDG PET‐CT) demonstrated markedly increased metabolic activity in serosal surfaces including pericardium, pleura, and renal fascia, as well as diffuse uptake along vascular walls, particularly the entire aorta.
Ribero‐Vargas Daniel Andres   +2 more
wiley   +1 more source

Female Genital Tuberculosis, Ghana: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Female genital tuberculosis is an underdiagnosed cause of infertility and amenorrhea in tuberculosis‐endemic regions. Hysteroscopy combined with histopathology can confirm the diagnosis even when molecular testing is negative. Clinicians should maintain a high index of suspicion and pursue multimodal diagnostic evaluation in women with ...
Anthony K. Dah   +6 more
wiley   +1 more source

Idiopathic Granulomatous Mastitis in a Nulliparous Woman With Autism Spectrum Disorder Receiving Long‐Term Psychotropic Treatment and Normal Serum Prolactin Level: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Idiopathic granulomatous mastitis (IGM) is a rare inflammatory breast disorder, primarily attributed to immunological dysregulation, hormonal imbalances, or fertility‐related conditions. We report a 26‐year‐old female with autism spectrum disorder (ASD) under long‐term multidrug psychotropic treatment who developed IGM.
Esmat Davoudi‐Monfared   +5 more
wiley   +1 more source

A 50‐year‐old man with a 12‐year history of extensive pachymeningeal thickening

open access: yes
Brain Pathology, Volume 36, Issue 4, July 2026.
Alyssa M. Lee   +3 more
wiley   +1 more source

Exudative Retinal Detachments: A Rare Adverse Effect of Topiramate

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Topiramate‐induced multifocal exudative retinal detachment is a rare but potentially vision‐threatening adverse effect. We report a 59‐year‐old woman with idiopathic intracranial hypertension who developed painless bilateral blurry vision and color desaturation 8 days after initiation of topiramate 25 mg twice daily.
Sarah Aljefri   +3 more
wiley   +1 more source

Sarcoidosis and Polymethyl Methacrylate (PMMA) Granulomas following COVID-19 Vaccination (ChAdOx1): Successful Treatment with Tofacitinib

open access: yesIndian Journal of Dermatology
Sarcoidosis and complications related to fillers have been reported following the COVID-19 vaccination. Additionally, cutaneous sarcoidosis has been observed around polymethyl methacrylate (PMMA) injection sites.
Mayra Ianhez   +5 more
doaj   +1 more source

Assessing the Effect of Adalimumab in Granuloma Annulare: A Case Series and Literature Review

open access: yesJEADV Clinical Practice, Volume 5, Issue 2, Page 651-655, June 2026.
ABSTRACT Granuloma annulare (GA) is a benign granulomatous skin disorder for which standardized treatment guidelines are lacking due to limited evidence. Adalimumab, a TNF‐α inhibitor, shows promise as a therapeutic option due to its potential to disrupt GA granulomas.
Adriana Caixinha Valorenzos   +2 more
wiley   +1 more source

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