Results 21 to 30 of about 122,915 (293)

Design of a randomized controlled trial to evaluate effectiveness of methotrexate versus prednisone as first-line treatment for pulmonary sarcoidosis: the PREDMETH study

open access: yesBMC Pulmonary Medicine, 2020
Background Treatment of pulmonary sarcoidosis is recommended in case of significant symptoms, impaired or deteriorating lung function. Evidence-based treatment recommendations are limited and largely based on expert opinion.
Vivienne Kahlmann   +10 more
doaj   +1 more source

Pleural CD14+ monocytes/macrophages of healthy adolescents show a high expression of metallothionein family genes

open access: yesEuropean Journal of Immunology, Volume 53, Issue 1, January 2023., 2023
Modern surgical (technical) possibilities enable pleural macrophage isolation and analyses regardless the person`s age. Transcriptome profiling of macrophages from healthy or sick individuals revealed that these cells express high levels of metallothioneins, metal‐binding proteins that are involved in heavy metal detoxification, antioxidative defense ...
Nagoud Schukfeh   +11 more
wiley   +1 more source

Effect on haemostasis of different replacement fluids during therapeutic plasma exchange—A comparative multicentre observational study

open access: yesJournal of Clinical Apheresis, Volume 37, Issue 6, Page 534-543, December 2022., 2022
Abstract Introduction Therapeutic plasma exchange (TPE) is used for several chronic conditions with little evidence on the efficacy and safety of different choice of replacement fluid. Measurement of haemostasis, particularly in vitro thrombin generation, could play a role in determining the immediate efficacy of different fluid replacement.
Ruchika Kohli   +6 more
wiley   +1 more source

SARCOIDOSIS [PDF]

open access: yesThe Lancet, 1960
The historical background to the disorder is unfolded. It was originally regarded as a dermatological curiosity, and later sarcoidosis was recognized as a disorder diffusely involving most tissues of the body. Clinical syndromes described include those presenting to the dermatologist, ophthalmologist, chest physician and radiologist, gastroenterologist
openaire   +8 more sources

Biomarkers in the Diagnosis and Prognosis of Sarcoidosis: Current Use and Future Prospects

open access: yesFrontiers in Immunology, 2020
Sarcoidosis is a heterogeneous disease in terms of presentation, duration, and severity. Due to this heterogeneity, it is difficult to align treatment decisions.
Raisa Kraaijvanger   +3 more
semanticscholar   +1 more source

King's Sarcoidosis Questionnaire (KSQ) - Validation study in Serbian speaking population of sarcoidosis patients.

open access: yesPLoS ONE, 2023
IntroductionSarcoidosis is a multiorgan, multisystem chronic disease of unknown etiology and unpredictable course. Health status is reduced in sarcoidosis and assessing it is a difficult multitask effort due to many faces this disease might have ...
Mihailo Stjepanovic   +7 more
doaj   +1 more source

Sarcoidosis: Causes, Diagnosis, Clinical Features, and Treatments

open access: yesJournal of Clinical Medicine, 2020
Sarcoidosis is a multisystem granulomatous disease with nonspecific clinical manifestations that commonly affects the pulmonary system and other organs including the eyes, skin, liver, spleen, and lymph nodes. Sarcoidosis usually presents with persistent
Rashi Jain   +4 more
semanticscholar   +1 more source

Characteristics and management of ocular sarcoidosis

open access: yesImmunological Medicine, 2022
Sarcoidosis is a chronic inflammatory disease of unknown etiology that affects many systemic organs, including the eye. The eye is the second most frequently affected organ in patients with sarcoidosis after lung disease. Approximately 30–50% of patients
Hiroshi Takase
doaj   +1 more source

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