Results 1 to 10 of about 391,439 (237)
Much of our knowledge regarding cancer immunotherapy has been derived from sarcoma models. However, translation of preclinical findings to bedside success has been limited in this disease, though several intriguing clinical studies hint at the potential efficacy of this treatment modality.
Gouw, Launce G+3 more
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Abstract ASCO 2001 was a banner year for innovative systemic therapy for sarcomas. Imatinib mesylate (STI571, GleevecTM) shows clear activity not only in chronic myelogenous leukemia, for which the drug received Food and Drug Administration approval, but also in gastrointestinal stromal tumors as well, by virtue of imatinib mesylate ...
E O., Dickens, J M., McGeeE
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Sarcomas are a diverse group of malignancies originating in the connective tissue. The approach of a patient with a mass suspect for sarcoma starts with performing a biopsy to obtain tissue for evaluation by pathology. The main role of the current imaging modalities, in general, is to recognize patients with typically benign disease, in whom further ...
Ceyssens, Sarah, Stroobants, Sigrid
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A 59-year-old white woman, SC, after being treated for pneumonia, presented with an increase in the size of lymph nodes. The immunohistochemical examination diagnosed histiocytic sarcoma. Relapse occurred 12 months after starting chemotherapy. The patient evolved with febrile neutropenia, septic shock and death.
Machado, Eduardo Silva+4 more
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The Epidemiology of Sarcoma [PDF]
AbstractSarcomas account for over 20% of all pediatric solid malignant cancers and less than 1% of all adult solid malignant cancers. The vast majority of diagnosed sarcomas will be soft tissue sarcomas, while malignant bone tumors make up just over 10% of sarcomas. The risks for sarcoma are not well-understood.
Zachary Burningham+3 more
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In summary, sarcomas represent a heterogeneous group of diseases, each with a unique and complex pathway to carcinogenesis. The challenge of the next decade will be to define sarcomas according to their unique molecular alterations and to treat them accordingly. The implementation of genomic technologies such as microarray analysis will facilitate this
Crystal L. Mackall+2 more
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Synovial sarcoma: the misdiagnosed sarcoma
Synovial sarcoma is a rare and highly malignant soft tissue sarcoma. The inconspicuous and diversity of its early symptoms make it a highly misdiagnosed disease. The management of synovial sarcomas is challenging as they are rare and have a poor prognosis. Early and correct diagnosis and treatment are critical for clinical outcomes.
Chengxiang Li+4 more
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Ewing sarcoma is the second most frequent bone tumour of childhood and adolescence that can also arise in soft tissue. Ewing sarcoma is a highly aggressive cancer, with a survival of 70-80% for patients with standard-risk and localized disease and ~30% for those with metastatic disease.
Grünewald, Thomas G. P.+8 more
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Budny Agnieszka, Litak Jakub, Kulesza Bartłomiej, Czyżewski Wojciech, Grochowski Cezary. Ewing`s Sarcoma. Journal of Education, Health and Sport. 2017;7(6):265-272. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.804631 http://ojs.ukw.edu.pl/index.php/johs/article/view/4534 The journal has had 7 points in Ministry of Science and ...
Cezary Grochowski+4 more
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