Indian Journal of Medical and Paediatric Oncology, 2019 Endometrial stromal sarcomas (ESSs) are a rare entity, constituting 10% of all uterine sarcomas and 0.2% of all uterine malignancies. We report a very rare case of high-grade endometrial stromal sarcoma in a 34-year-old female with fibroids uterus ...
Kanika Jain +3 more
doaj +1 more source
Case Reports in Obstetrics and Gynecology, 2020 Morcellation of benign uterine tumors allows for removal of the tumors via minimally invasive laparoscopic procedures. However, in rare cases, morcellation has been associated with upstaging of unexpected malignancies.
Daniel P. Stefanko +2 more
doaj +1 more source
Potential Targets' Analysis Reveals Dual PI3K/mTOR Pathway Inhibition as a Promising Therapeutic Strategy for Uterine Leiomyosarcomas-an ENITEC Group Initiative [PDF]
, 2017 Purpose: Uterine sarcomas are rare and heterogeneous tumors characterized by an aggressive clinical behavior. Their high rates of recurrence and mortality point to the urgent need for novel targeted therapies and alternative treatment strategies. However,
Amant, Frederic +30 more
core +2 more sources
Histone deacetylase inhibitor vorinostat suppresses the growth of uterine sarcomas in vitro and in vivo [PDF]
, 2010 Background Uterine sarcomas are very rare malignancies with no approved chemotherapy protocols. Histone deacetylase (HDAC) inhibitors belong to the most promising groups of compounds for molecular targeting therapy.
Andelko Hrzenjak +6 more
core +1 more source
Immunohistochemistry of endometrial stromal sarcoma
Human Pathology, 1991 Twenty-three cases (12 low grade, 11 high grade) of endometrial stromal sarcoma were studied with monoclonal antibodies to vimentin, keratin, desmin, muscle actin, epithelial membrane antigen, and collagen type IV, using the avidin-biotin immunoperoxidase method. Tumors were highly variable in the expression of these antigens.
A I, Farhood, J, Abrams
openaire +2 more sources
Enhanced expression of the stemness-related factors OCT4, SOX15 and TWIST1 in ectopic endometrium of endometriosis patients [PDF]
, 2016 Background Current evidence suggests that endometrial-derived stem cells, spilled in the peritoneal cavity via retrograde menstruation, are key players in the establishment of endometriotic lesions. The aim of this study was to determine the presence and
Berthold Streubel +10 more
core +3 more sources
Mixed low grade and high grade endometrial stromal sarcoma of uterus: Differences on immunohistochemistry and chromosome in situ hybridisation [PDF]
, 1996 A case of a 64 year old woman with a tumour of the uterus is reported. The patient presented with postmenopausal bleeding and subsequently underwent total hysterectomy and bilateral salpingooophorectomy.
Cheung, ANY, Chung, LP, Khoo, US, Ng, WF
core
UK guidelines for the management of soft tissue sarcomas [PDF]
, 2016 Soft tissue sarcomas (STS) are rare tumours arising in mesenchymal tissues, and can occur almost anywhere in the body. Their rarity, and the heterogeneity of subtype and location means that developing evidence-based guidelines is complicated by the ...
Dangoor, A +5 more
core +1 more source
Human Pathology: Case Reports, 2019 High-grade endometrial stromal sarcoma harboring ZC3H7B-BCOR fusion is a newly defined entity in gynecologic pathology featuring a set of distinct histopathological and molecular features.
Jerry C. Nagaputra +4 more
doaj +1 more source
Cellular retinol-binding protein-1 expression in endometrial stromal cells: physiopathological and diagnostic implications [PDF]
, 2004 Cellular retinol-binding protein-1 (CRBP-1) contributes to the maintenance of the differentiated state of the endometrium through retinol bioavailability regulation.
Ciucci, A +7 more
core +1 more source