Results 61 to 70 of about 9,292 (183)

Lack of Differences in the Pharmacokinetics of Therapeutic Monoclonal Antibodies Between Japanese and Non‐Japanese Individuals

The Journal of Clinical Pharmacology, Volume 66, Issue 8, August 2026.
Abstract Evaluation of the pharmacokinetics (PK) of new drugs in Japanese individuals is regularly requested by the Japanese regulatory agency prior to participation in global clinical trials or for bridging approaches for regulatory approval. However, the need for PK assessments in the Japanese population may be less compelling for monoclonal ...
Paridhi Gupta, Ashish Sharma, Bernd Meibohm   +2 more
wiley   +1 more source

Amino Acid and Lipid Metabolism in Cancer: Mechanisms and Therapeutic Opportunities

MedComm, Volume 7, Issue 8, August 2026.
Amino Acid and lipid metabolism in cancer: (A) Regulation of Amino acid transportation and metabolism in cancer. (B) The core organization of lipid metabolic reprogramming in cancer and their functional consequences. ABSTRACT Metabolic reprogramming is a defining feature of cancer and a major contributor to immune escape.
Zixu Wang, Xin Fu, Jingchao Bai, Yanguo Liu, Kai Huang   +4 more
wiley   +1 more source

A Case of Malignant Low Grade Endometrial Stromal Sarcoma and Review of The Literature

National Journal of Community Medicine, 2011
Low grade endometrial stromal sarcoma is a rare pelvic malignancy that arises from the endometrium. This article describes the morphological features of one such tumour discovered as finding in a hysterectomy specimen of a 32-year lady with a clinical ...
Amrish N Pandya, Arpita Nishal, Hemali Tailor   +2 more
doaj  

Lysine l‐Lactylation: Bridging Metabolism, Chromatin and Disease

Cell Proliferation, Volume 59, Issue 8, August 2026.
Enzymatic regulation of KL‐la. The enzymatic regulation of KL‐la involves two distinct pathways for L‐lactate accumulation: intracellular production through glycolysis‐derived pyruvate conversion by lactate dehydrogenase (LDH) or direct cellular uptake via monocarboxylate transporters (MCTs). These L‐lactate pools fuel two distinct lactylation pathways—
Anoosha Malik, Muhammad Dilawar, Junguang Liao, Jie Zheng, Qitao Qian, Ming Xu, Sisi Lin, Xiaobo Zhu, Qiuwei Ge, Limin Jin, Guiqian Chen   +10 more
wiley   +1 more source

A Case Report of a Severely Aggressive Uterine Sarcoma at an Unusual Age [PDF]

Journal of Kerman University of Medical Sciences, 2016
Uterine sarcomas are very unique tumors with mesodermial origin and accounting for 2-6% of uterine cancers. In general, uterine sarcomas are the most malignant tumors of the uterus.
zahra honarvar, Mohades Peydayesh
doaj  

Endometrial Stromal Nodule: Report of a Case

Case Reports in Medicine, 2011
Endometrial stromal nodule (ESN) is the least common of the endometrial stromal tumors. They are rare neoplasms which are diagnosed in most instances by light microscopy. Although such nodules are benign, hysterectomy has been considered the treatment of
F. Z. Fdili Alaoui, H. Chaara, H. Bouguern, M. A. Melhouf, H. Fatemi, A. Belmlih, Afaf Amarti   +6 more
doaj   +1 more source

A Case of Retroperitoneal Metastases That Occur 14 Years After Surgery

Urology Case Reports, 2016
Endometrial Stromal Sarcomas are rare malignant tumours of the uterus. We report the case of incidental finding of Low-Grade Endometrial Stromal Sarcoma (LGESS) that metastasized to the retroperitoneum 14 years after the original surgery in a 72-year-old
Masjensen Argadjendra, Nariman Ahmadi, Celi Varol   +2 more
doaj   +1 more source

From Diagnosis to Management: A Rare Case of Disseminated Low-Grade Endometrial Stromal Sarcoma with Extensive Extrauterine Spread

Indonesian Journal of Obstetrics and Gynecology
Objective: To report a rare case of low-grade endometrial stromal sarcoma; which was found not only in the uterus but also in several extrauterine sites, such as the ovary, omentum, and jejuno-ileum. In this article, we provided the management performed,
Adrian Djatikusumo, Yulian Prastisia, Iwan Kurnia Effendi, Wina Kanya Wasystha   +3 more
doaj   +1 more source

High-Grade Endometrial Stromal Sarcoma with a Mucoid Grossly Feature: A Case Report of a 69-YearOld Iranian patient

Case Reports in Clinical Practice
Reporting clinical cases of high-grade endometrial stromal sarcoma tumors is essential for a better understanding of their natural course and for the development of appropriate diagnostic and treatment strategies.
Faraz Mahdizadeh, Mir Mehdi Chinifroush-Asl, Farzad Heidary, Hamid Hataminia   +3 more
doaj   +1 more source

Cystic appearance of low-grade endometrial stromal sarcoma in the right atrium: case report

Cardiovascular Ultrasound, 2011
A 71-year-old woman presented with a right adnexal solid mass invading the right gonadal vein and inferior vena cava up to the hepatic veins revealed by CT and confirmed by MRI.
Russ Paul, Sederberg James, Wood Cristina L, Seres Tamas   +3 more
doaj   +1 more source