Multi-platform profiling of over 2000 sarcomas: Identification of biomarkers and novel therapeutic targets [PDF]
, 2015 Background: Drug development in sarcoma has been hampered by the rarity and heterogeneity of the disease and lack of predictive biomarkers to therapies.
Chen, Wangjuh +7 more
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World Journal of Surgical Oncology, 2006 Background Endometrial stromal sarcoma (ESS) is a rare disease with probably less than 700 new cases in the USA or Europe per year. The aim of this study was to evaluate the behavior of low-grade endometrial stromal sarcoma (LGESS) in relation to their ...
Shariat Mamak +3 more
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Journal of Medical Case Reports, 2021 Background Low-grade endometrial stromal sarcoma is a rare neoplastic growth in the uterine cavity, representing less than 1% of uterine tumors. Such tumors usually affect premenopausal and perimenopausal women, with a mean age of 46 years.
Omar F. Altal +6 more
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Müllerian Adenosarcoma of the Urinary Bladder: Clinicopathologic and Immunohistochemical Features with Novel Genetic Aberrations [PDF]
, 2017 Müllerian adenosarcoma is a biphasic neoplasm most commonly of the uterus and less frequently of the ovary. It has been rarely described to occur in other sites such as peritoneum and liver.
Cheng, Liang +8 more
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Metformin as a Therapeutic Target in Endometrial Cancers. [PDF]
, 2018 Endometrial cancer is the most common gynecologic malignancy in developed countries. Its increasing incidence is thought to be related in part to the rise of metabolic syndrome, which has been shown to be a risk factor for the development of ...
Johnson, Jennifer +6 more
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Primary replication and invasion of the bovine gammaherpesvirus BoHV-4 in the genital mucosae [PDF]
, 2017 Bovine herpesvirus 4 (BoHV-4) is a gammaherpesvirus that is widespread in cattle. Ex vivo models with bovine genital tract mucosa explants were set up to study molecular/cellular BoHV-4-host interactions.
Bogado Pascottini, Osvaldo Américo +6 more
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Pulmonary metastases of uterine endometrial stromal sarcoma in a young patient: An extreme rarity
Human Pathology: Case Reports, 2017 Endometrial stromal sarcoma (ESS) is a rare malignant tumor of the endometrium, usually seen in perimenopausal females. We report a case of ESS in a 24 year old woman, presenting as rapid enlargement of a uterine fibroid associated with irregular and ...
Sonia Chhabra +4 more
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Endometrial Stromal Sarcomas: A Revision of Their Potential as Targets for Immunotherapy
Vaccines, 2018 Endometrial stromal sarcomas are a subtype of uterine sarcomas that are characterized by recurrent chromosomal translocations, resulting in the expression of tumor-specific fusion proteins that contribute to their tumorigenicity.
Sandra Tuyaerts, Frédéric Amant
doaj +1 more source
Dose-response effect of interleukin (IL)-1β, tumour necrosis factor (TNF)-α, and interferon-γ on the in vitro production of epithelial neutrophil activating peptide-78 (ENA-78), IL-8, and IL-6 by human endometrial stromal cells [PDF]
, 2018 Purpose: The production of epithelial neutrophil activating peptide-78 (NA-78) and the interleukins IL-8 and IL-6 by endometrial stromal cells is stimulated by pro-inflammatory interleukin-1 (IL-1) and tumour necrosis factor-α (TNF-α).
Bersinger, Nick +4 more
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FISH molecular testing in cytological preparations from solid tumors [PDF]
, 2014 Many of the exciting new developments in solid tumor molecular cytogenetics impact classical and molecular pathology. Fluorescence in situ hybridization to identify specific DNA target sequences in nuclei of non-dividing cells in solid neoplasms has ...
CARIA, PAOLA, VANNI, ROBERTA
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