Abstract Viral infections play a significant role in cancer development, making detecting viral signatures a promising approach for early cancer diagnosis. Circulating free DNA (cfDNA), released into the bloodstream by tumors and other cells, has emerged as a powerful biomarker for non‐invasive cancer screening.
Richard Donkor Amponsah+4 more
wiley +1 more source
Angiosarcoma-like Kaposi sarcoma represents a recently delineated rare histomorphologic variant of Kaposi sarcoma that can be difficult to distinguish from other vasoproliferative lesions. Conventional lesions of Kaposi sarcoma encompass patches, plaques,
Jasmine Gill+3 more
doaj +1 more source
Remembering the forgotten child: the role of immune checkpoint inhibition in patients with human immunod eficiency virus and cancer. [PDF]
Patients with human immunodeficiency virus (HIV) infection have a high risk of developing virally-mediated cancers. These tumors have several features that could make them vulnerable to immune checkpoint inhibitors (ICIs) including, but not limited to ...
Adashek, Jacob J+3 more
core
Targeting of Prosurvival Pathways as Therapeutic Approaches against Primary Effusion Lymphomas: Past, Present, and Future [PDF]
Constitutively activated prosurvival pathways render cancer cells addicted to their effects. Consequently they turn out to be the Achilles’ heels whose inhibition can be exploited in anticancer therapy.
CIRONE, Mara+6 more
core +4 more sources
Angiogenesis, Kaposi’s sarcoma and Kaposi’s sarcoma-associated herpesvirus [PDF]
Tumor angiogenesis is the uncontrolled growth of blood vessels in tumors, serving to supply nutrients and oxygen, and remove metabolic wastes. Kaposi's sarcoma (KS), a multifocal angioproliferative disorder characterized by spindle cell proliferation, neo-angiogenesis, inflammation, and edema, is associated with infection by Kaposi's sarcoma-associated
Shou-Jiang Gao+6 more
openaire +3 more sources
Plaque‐Like Dermatofibroma: A Case Report and a Review of the Literature With a Focus on Dermoscopy
ABSTRACT Plaque‐like dermatofibroma (PLDF) is a rare clinical variant of dermatofibroma (DF), characterised by flat, infiltrative lesions, often larger than 50 mm in diameter and located on the trunk or lower extremities. A 44‐year‐old male presented to our clinic with a 20 cm brownish plaque with peripheral satellite lesions on the right antecubital ...
Francesco Cavallo+7 more
wiley +1 more source
Diagnostic dilemma in Kaposi’s sarcoma
Kaposi′s sarcoma is described as cutaneous and extracutaneous neoplasm predominantly affecting older individuals. Though earlier uncommon and endemic to certain African areas, its incidence is on a rise due to infections with human immunodeficiency virus
Rao B.S Satish+4 more
doaj +1 more source
Penile Kaposi sarcoma: A case of complete resolution with highly active antiretroviral therapy alone [PDF]
Kaposi sarcoma remains an important cause of morbidity in HIV-infected patients. Regardless of the recent pharmacological progress, treatment of this malignancy is still disappointing.
Alves, R.+6 more
core +1 more source
Bortezomib promotes KHSV and EBV lytic cycle by activating JNK and autophagy [PDF]
KSHV and EBV are gammaherpesviruses strictly linked to human cancers. Even if the majority of cancer cells harbor a latent infection, the few cells that undergo viral replication may contribute to the pathogenesis and maintenance of the virus-associated ...
Cirone, Mara+7 more
core +2 more sources
Rare Case of Vallecular Hemangioma With Complete Regression in an Adult Patient
A rare case of spontaneous regression of a pedunculated vallecular hemangioma in a 55‐year‐old male is presented. Following an incisional biopsy, the lesion regressed completely within three weeks, confirmed by imaging and direct laryngoscopy. This case highlights an unusual clinical outcome and raises questions about the mechanisms underlying ...
Guilherme Reimann Agne+8 more
wiley +1 more source