Results 61 to 70 of about 37,842 (235)

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source

Clinical observation of Kaposi sarcoma associated with HIV in a patient with disseminated pulmonary tuberculosis, viral hepatitis B and C

Лечащий Врач, 2021
The article describes the clinical observation of Kaposi sarcoma associated with HIV in a patient with disseminated pulmonary tuberculosis, viral hepatitis B and C.
N. V. Nelidova, N. V. Kuzmina, Yu. E. Rusak, E. N. Efanova   +3 more
doaj   +1 more source

Targeting of Prosurvival Pathways as Therapeutic Approaches against Primary Effusion Lymphomas: Past, Present, and Future [PDF]

, 2015
Constitutively activated prosurvival pathways render cancer cells addicted to their effects. Consequently they turn out to be the Achilles’ heels whose inhibition can be exploited in anticancer therapy.
CIRONE, Mara, FAGGIONI, Alberto, FARINA, Antonella, GONNELLA, ROBERTA, GRANATO, Marisa, SANTARELLI, Roberta, TRIVEDI, PANKAJ   +6 more
core   +4 more sources

Absence of DNA viruses in ameloblastomas

European Journal of Oral Sciences, EarlyView.
Abstract Ameloblastomas (ABs) are rare odontogenic benign tumors. Although studies of the molecular pathogenesis have revealed the presence of mutations and altered gene expression, the etiology is unresolved. Viruses cause 10%–15 % of cancers, but their potential role within benign tumors is less studied.
Maria K. Jauhiainen, Jetta Kelppe, Maria Söderlund‐Venermo, Antti A. Mäkitie, Saku T. Sinkkonen, Jaana Hagström   +5 more
wiley   +1 more source

Understanding the implementation of patient navigation for adults living with HIV: A scoping review of components, equity considerations and lessons learned

HIV Medicine, EarlyView.
Abstract Background People living with HIV navigate complex medical and social challenges that impact engagement in care, including stigma, poverty and systemic inequities. Patient navigation has emerged as a promising approach to improve linkage, retention and adherence across the HIV care continuum.
Kristina M. Kokorelias, Christine L. Sheppard, Andrew Eaton, Marina B. Wasilewski, Sander L. Hitzig, Dean Valentine, Mackenzie Earle, Carolina Navas, David Gerstle, Maurita T. Harris, Luxey Sirisegaram   +10 more
wiley   +1 more source

Bortezomib promotes KHSV and EBV lytic cycle by activating JNK and autophagy [PDF]

, 2017
KSHV and EBV are gammaherpesviruses strictly linked to human cancers. Even if the majority of cancer cells harbor a latent infection, the few cells that undergo viral replication may contribute to the pathogenesis and maintenance of the virus-associated ...
Cirone, Mara, Faggioni, Alberto, Gilardini Montani, Maria Saveria, Gonnella, Roberta, Granato, Marisa, Romeo, Maria Anele, Santarelli, Roberta, Tiano, Mariangela Sara   +7 more
core   +2 more sources

OX40/OX40L modulation: A target for regulating T cells in cutaneous inflammatory disorders

Journal of the European Academy of Dermatology and Venereology, EarlyView.
OX40 and OX40L are a co‐stimulatory immune checkpoint pair. Modulation of this pair impacts multiple immune phenotypes and is an attractive target for immunotherapy in dermatological disorders. Trials are underway with the majority in atopic dermatitis and currently in phase 3 trials.
Aditya K. Gupta, Julia Steriopoulos, Vasiliki Economopoulos, Paradi Mirmirani, Vincent Piguet   +4 more
wiley   +1 more source

Sarcoma de Kaposi ocular. Presentación de un caso.

Gaceta Médica Espirituana, 2012
Fundamento: el sarcoma de Kaposi es una enfermedad tumoral descrita por primera vez por el médico húngaro Morita Kaposi en 1872 y puede presentarse con marcada frecuencia en pacientes seropositivos como enfermedad marcadora de sida. Presentación de caso:
Axel López Valdés, Vivian María Couce Herrera, Erians Valdés Pérez, Roxana María Almanza Alarcón, Edelby Escobar Carmona   +4 more
doaj  

Prevalence and predictors of kaposi sarcoma herpes virus seropositivity: a cross-sectional analysis of HIV-infected adults initiating ART in Johannesburg, South Africa [PDF]

, 2011
Background Kaposi sarcoma (KS) is the most common AIDS-defining tumour in HIV-infected individuals in Africa. Kaposi sarcoma herpes virus (KSHV) infection precedes development of KS.
Maskew, Mhairi, Macphail, A Patrick, Whitby, Denise, Egger, Matthias, Wallis, Carole L, Fox, Matthew P   +5 more
core   +2 more sources

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source