Results 61 to 70 of about 36,698 (211)

Clinical observation of Kaposi sarcoma associated with HIV in a patient with disseminated pulmonary tuberculosis, viral hepatitis B and C

Лечащий Врач, 2021
The article describes the clinical observation of Kaposi sarcoma associated with HIV in a patient with disseminated pulmonary tuberculosis, viral hepatitis B and C.
N. V. Nelidova, N. V. Kuzmina, Yu. E. Rusak, E. N. Efanova   +3 more
doaj   +1 more source

Mapping protein–protein interactions by mass spectrometry

Mass Spectrometry Reviews, EarlyView.
Abstract Protein–protein interactions (PPIs) are essential for numerous biological activities, including signal transduction, transcription control, and metabolism. They play a pivotal role in the organization and function of the proteome, and their perturbation is associated with various diseases, such as cancer, neurodegeneration, and infectious ...
Xiaonan Liu, Lawrence Abad, Lopamudra Chatterjee, Ileana M. Cristea, Markku Varjosalo   +4 more
wiley   +1 more source

Speculations on the clinical significance of asymptomatic viral infections [PDF]

, 2016
A detailed understanding of asymptomatic chronic viral infections is critical to analyse their pathogenesis, assess the severity and burden of disease and, where required, optimize public health control measures.
Gentile, Giuseppe, Micozzi, Alessandra
core   +1 more source

Kaposi Sarcoma

Archives of Pathology & Laboratory Medicine, 2013
Kaposi sarcoma (KS) is a low-grade vascular tumor associated with Kaposi sarcoma herpesvirus/human herpesvirus 8 (KSHV/HHV8) infection. Kaposi sarcoma lesions predominantly present at mucocutaneous sites, but may involve all organs and anatomic locations. Recognized epidemiologic-clinical forms of KS include classic, African (endemic), AIDS-associated (
Oana, Radu, Liron, Pantanowitz
openaire   +2 more sources

Exploring the Hemoglobin T to R2 Path Using Gaussian Elastic Network Correlation Map Distance

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Proteins are dynamic and undergo conformational changes. These changes may affect the motions executed by different regions of the proteins and are reflected in the motion correlation map. A method to accurately measure these changes is presented and exemplified on a set of tetrameric Hemoglobin structures.
Yuval Valenci, Dror Tobi
wiley   +1 more source

Robustness of a convolutional neural network trained on dermoscopic images and challenged with close‐up images

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and Objectives Deep learning‐convolutional neural networks (DL‐CNNs) have demonstrated high diagnostic accuracy within the domain of dermoscopy. However, many clinical settings lack dermoscopic devices, requiring reliance on close‐up images. This study evaluates the robustness of a DL‐CNN trained on dermoscopic images when challenged
Anastasia Sophie Vollmer, Julia Katharina Winkler, Katharina Susanne Kommoss, Wilhelm Stolz, Albert Rosenberger, Alexander Enk, Holger Andreas Haenssle   +6 more
wiley   +1 more source

Risk factors for high anti-HHV-8 antibody titers (≥1:51,200) in black, HIV-1 negative South African cancer patients: a case control study [PDF]

, 2003
Background: Infection with human herpesvirus 8 (HHV-8) is the necessary causal agent in the development of Kaposi's sarcoma (KS). Infection with HIV-1, male gender and older age all increase risk for KS.
BM Friedman, C Boshoff, C Boshoff, D Serraino, D Whitby, DH Kedes, Dimitra Bourboulia, EP Zorrilla, F Sitas, F Vitale, Freddy Sitas, G de-The, G de-The, G Rezza, GR Simpson, H Renwick, J Iscovich, J Ziegler, Janet M Wojcicki, JJ Goedert, JL Ziegler, JL Ziegler, KA Staskus, L Rainbow, Lara Stein, LD Baker, M Dedicoat, Margaret I Urban, Martin Hale, Moosa Patel, P Cook-Mozaffari, P Kellam, Paul Ruff, PS Moore, R Greenblatt, R Newton, R Newton, R Tedeschi, Ranjan Sur, RJ Biggar, Rob Newton, RP Stowe, S Lemeshow, S Plancoulaine, SJ Gao, STATA, Statistics South Africa, TH Bothwell, TH Bothwell, VR Gordeuk, Y Chang, Z Grossman   +51 more
core   +2 more sources

Bronchopulmonary Kaposi's sarcoma

Respiratory Medicine Case Reports, 2015
Kaposi's sarcoma (KS) is a highly vascular tumour, which was first described by the Hungarian dermatologist Moritz Kaposi Kohn before the discovery of the human immunodeficiency virus (HIV). Historically, KS has been linked to immunosuppression or to elderly male patients, especially in relation to diffuse cutaneous KS.
Bashar, Nada, Innes, Nicholas, Orrell, Julian   +2 more
openaire   +3 more sources

Ubiquitination dynamics in human tumour viruses: Viral infection, oncogenesis and antiviral therapy

The FEBS Journal, EarlyView.
The ubiquitin system is essential for cellular homeostasis and regulates many processes. Viruses, including oncogenic ones, exploit or evade this system to survive and replicate. This review explores how human tumour viruses manipulate the ubiquitination system to complete their life cycle, evade immunity and promote cancer.
Oscar Trejo‐Cerro, Martina Bergant Marušič, Justyna Broniarczyk   +2 more
wiley   +1 more source

Limited asymptomatic carriage of Pneumocystis jiroveci in human immunodeficiency virus-infected patients [PDF]

, 2003
Forty-seven bronchoalveolar lavage fluid samples from 16 human immunodeficiency virus (HIV)-infected patients were used to test the latency model of Pneumocystis infection in the human host.
Ambrose, HE, Denis, CM, Lindley, AR, Miller, RF, Wakefield, AE   +4 more
core