Results 231 to 240 of about 738,044 (342)

Identification of diverse activating mutations of the RAS-MAPK pathway in histiocytic sarcoma

Modern Pathology, 2019
Vignesh Shanmugam, G. Griffin, E. Jacobsen, C. Fletcher, L. Sholl, J. Hornick   +5 more
semanticscholar   +1 more source

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

AVN944 Elicits Apoptotic Responses and Impedes Tumorigenic Potential in Ewing's Sarcoma Cells. [PDF]

Int J Biol Sci
Lim H, Lee S, Kim G, Lee EJ, Kim J.
europepmc   +1 more source

Ewing's sarcoma of the calcaneus bone [PDF]

, 2015
Atul Tiwari, Yogesh Sisodia, Yogesh Gautam   +2 more
openalex   +1 more source

Linking the NETSARC+ National Sarcoma Database With the SNDS to Evaluate Adjuvant and/or Neoadjuvant Therapy: Report on the Linkage Process and Result (Health Data Hub's DEEPSARC Pilot Project). [PDF]

Fundam Clin Pharmacol
Drezen E, Happe A, Thevenet V, Penel N, Gouin F, Le Loarer F, Du Bouexic De Pinieux G, Crochet H, Airiau CC, Ducimetiere F, Mathoulin Pelissier S, Blay JY, Oger E.   +12 more
europepmc   +1 more source

An aggressive soft-tissue sarcoma of the extremity: A myxofibrosarcoma, grade 3 (FNCLCC system)

Manuela Montatore, Federica Masino, Gianmichele Muscatella, Rossella Gifuni, Giacomo Fascia, Alessio Sciacqua, Giuseppe Guglielmi   +6 more
openalex   +1 more source

Improved survival using specialized multidisciplinary board in sarcoma patients

Annals of Oncology, 2017
Jean-Yves Blay, P. Soibinet, Nicolas Penel, E. Bompas, F. Duffaud, E. Stoeckle, O. Mir, J. Adam, C. Chevreau, S. Bonvalot, M. Ríos, P. Kerbrat, D. Cupissol, P. Anract, F. Gouin, J. Kurtz, C. Lebbé, N. Isambert, F. Bertucci, M. Toumonde, A. Thyss, S. Piperno-Neumann, P. Dubray-Longeras, P. Meeus, F. Ducimetière, A. Giraud, J. Coindre, I. Ray-Coquard, A. Italiano, A. Cesne   +29 more
semanticscholar   +1 more source

Genomic and Immune Correlates of EZH2 Expression and Activity in Olfactory Neuroblastoma

Head &Neck, EarlyView.
ABSTRACT Purpose Olfactory neuroblastoma (ONB) is a rare sinonasal malignancy with limited therapeutic options in the recurrent/metastatic setting; little is known regarding its responsiveness to immunotherapy. Inhibition of enhancer of zeste homolog 2 (EZH2) has been shown to improve T‐cell‐mediated killing and susceptibility to immune checkpoint ...
Elisabetta Xue, Tolulope Adeyelu, Harris Krause, Andrew Elliott, Ranee Mehra, Heloisa Soares, Emil Lou, Ari Vanderwalde, David Spetzler, Dara Bracken‐Clarke, Nyall R. London Jr., James L. Gulley, Charalampos S. Floudas   +12 more
wiley   +1 more source

Gene expression signature based screening identifies ribonucleotide reductase as a candidate therapeutic target in Ewing sarcoma

, 2016
Kelli L. Goss, David J. Gordon
openalex   +2 more sources

DNA methylation heterogeneity defines a disease spectrum in Ewing sarcoma

Nature Medicine, 2017
Nathan C. Sheffield, G. Pierron, J. Klughammer, Paul Datlinger, Andreas Schönegger, M. Schuster, J. Hadler, Didier Surdez, D. Guillemot, E. Lapouble, P. Fréneaux, J. Champigneulle, R. Bouvier, D. Walder, I. Ambros, C. Hutter, Eva Sorz, A. Amaral, E. de Álava, K. Schallmoser, D. Strunk, B. Rinner, B. Liegl-Atzwanger, B. Huppertz, A. Leithner, G. de Pinieux, P. Terrier, V. Laurence, J. Michon, R. Ladenstein, W. Holter, R. Windhager, U. Dirksen, P. Ambros, O. Delattre, H. Kovar, C. Bock, E. Tomazou   +37 more
semanticscholar   +1 more source