Results 251 to 260 of about 556,852 (338)

Patient‐ and caregiver‐reported barriers to radiotherapy for cancer in sub‐Saharan Africa—A survey of population‐based registries

International Journal of Cancer, EarlyView.
What's New? Low‐ and middle‐income countries have over 70% of the global cancer burden but 10% of the world's radiotherapy capacities. This population‐based multi‐country study explores the barriers to access experienced by cancer patients in sub‐Saharan Africa.
Eric Sven Kroeber, Tamara König, Ole Stöter, Biying Liu, Phoebe Mary Amulen, Margaret Borok, Gladys Chesumbai, Eric Chokunonga, Ima‐Obong Ekanem, Mahine Ivanga, Bakarou Kamaté, William Muller, Abidemi Omonisi, Jean‐Félix Peko, Mathewos Assefa, Furaha Serventi, Markus Wallwiener, Mazvita Muchengeti, Pablo Sandro Carvalho Santos, Donald Maxwell Parkin, Eva Johanna Kantelhardt, Nikolaus Christian Simon Mezger   +21 more
wiley   +1 more source

Clinical implications of PD‐L1 expression in oncogene‐driven NSCLC: Differential responses to targeted agents and immune checkpoint inhibitors

International Journal of Cancer, EarlyView.
What's New? PD‐L1 is a reliable biomarker for predicting immunotherapy efficacy in patients with non‐small‐cell lung cancer lacking oncogenic driver mutations. However, its significance in patients with driver mutations remains unclear. In this study of 273 patients with stage IV non–‐small‐cell lung cancer harboring diverse driver alterations and PD ...
Xiaoxiao Fan, Chenxi Wei, Minjun Rong, Shengnan Wang, Jiaying Wang, Xiaohan Wang, Xiao Han, Xue Meng   +7 more
wiley   +1 more source

Tumor‐educated platelets in cancer diagnostics and prognostics: A critical appraisal and roadmap for clinical translation

International Journal of Cancer, EarlyView.
Abstract Tumor‐educated platelets (TEPs) are emerging as a compelling frontier in liquid biopsy, functioning as dynamic, systemic sensors that sequester and process tumor‐derived biomolecules. This interaction imprints an integrated molecular signature of malignancy—spanning the transcriptome, proteome, lipidome, and crucially, the captured genome ...
Whi‐An Kwon, Min‐Kyung Lee, Eunyong Ahn, Heeyeon Kim, Yong Sang Song, Taejin Ahn   +5 more
wiley   +1 more source

Prediction of the individual risk for the development of brain metastases in patients with non‐oncogene‐addicted non‐small cell lung cancer: Real‐world data from the German prospective CRISP registry (AIO‐TRK‐0315)

International Journal of Cancer, EarlyView.
What's New? Estimating the risk of developing brain metastases may enable earlier diagnosis and treatment, potentially reducing morbidity and mortality. Using the prospective CRISP lung cancer registry, the authors developed and validated a point‐based classifier for the risk of developing first brain metastases in patients with advanced or metastatic ...
Fabian Acker, Katharina Wenger, Martin Reck, Cornelius F. Waller, Petra Hoffknecht, Andre Bethge, Arnd Nusch, Marcel Reiser, Christiane Bernhardt, Michael Bendel, Carolin Lennartz, Annette Fleitz, Martina Jänicke, Paula Ludwig, Annika Groth, Frank Griesinger, Michael Thomas, Wilfried E. E. Eberhardt, Martin Sebastian, for the CRISP Registry Group   +19 more
wiley   +1 more source

Development of a blood test for uterine sarcoma-Diagnosis and monitoring (DOORS-D and DOORS-M) studies. [PDF]

PLoS One
Casey A, Allsopp R, Shaw J, Cowley C, Stannard E, Griffin Y, Das I, Wadsley M, Darko N, Moss EL.   +9 more
europepmc   +1 more source

Diagnostic challenges in poorly differentiated primary synovial sarcoma of the breast. [PDF]

Discov Oncol
Kankaya B, Tatar Z, Altundal YE, Buyukasik S, Kapan S.   +4 more
europepmc   +1 more source

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source

Dual Left Atrial Masses Causing Inflow Obstruction: A Rare Presentation of Primary Cardiac Intimal Sarcoma. [PDF]

Vasc Health Risk Manag
Zhang X, Zhuo Y, Zhang D.
europepmc   +1 more source

Trabectedin and its potential in the treatment of soft tissue sarcoma

, 2008
Philippe A. Cassier, Armelle Dufresne, Jean‐Yves Blay, J amp eacute r amp ocirc me Fayette   +3 more
openalex   +1 more source

Chinese pan‐cancer patient genomic characteristics: A comprehensive analysis based on the National Cancer Center–Clinical Diagnostics Knowledgebase real‐world clinical sequencing cohort

Interdisciplinary Medicine, EarlyView.
We assembled National Cancer Center–Clinical Diagnostics Knowledgebase, a clinical genomic knowledgebase of 6935 tumors with matched normal samples, revealing key somatic alterations and actionable variants (70.2% of the cohort). Enrichment of certain different gene mutations was observed between Chinese and American populations, along with a strong ...
Hongrui Li, Shun Wang, Guowei Zhao, Jiangtao Li, Xin Li, Bingning Wang, Yi Zhang, Mengfei Yao, Lei Guo, Jianming Ying, Wenbin Li   +10 more
wiley   +1 more source