Results 101 to 110 of about 53,706 (285)

Ubiquitination dynamics in human tumour viruses: Viral infection, oncogenesis and antiviral therapy

The FEBS Journal, EarlyView.
The ubiquitin system is essential for cellular homeostasis and regulates many processes. Viruses, including oncogenic ones, exploit or evade this system to survive and replicate. This review explores how human tumour viruses manipulate the ubiquitination system to complete their life cycle, evade immunity and promote cancer.
Oscar Trejo‐Cerro, Martina Bergant Marušič, Justyna Broniarczyk   +2 more
wiley   +1 more source

SÍNDROME DE RECONSTITUIÇÃO IMUNE: UM OBSTÁCULO EM POTENCIAL NO MANEJO DO SARCOMA DE KAPOSI EM PACIENTES HIV POSITIVOS? – RELATO DE CASO

Revista da Sociedade Portuguesa de Dermatologia e Venereologia, 2014
A diversidade de apresentações clínicas da síndrome de reconstituição imune faz da mesma um desafio clínico, na medida em que é difícil o manejo de infecções oportunistas e outras condições clínicas relacionadas com tal síndrome.
Felipe Ladeira de Oliveira, Deborah Maria Brito Sírio, Gisele Cerutti, Natalia Barreiros de Natividade, Vinicius Martins de Menezes, Alice Miranda, Luna Azulay-Abulafia, José Augusto da Costa Nery   +7 more
doaj   +1 more source

Solid organ transplantation in people with HIV: Outcomes, obstacles and opportunities

HIV Medicine, EarlyView.
Abstract Objective People with HIV experience disparate access to solid organ transplantation (SOT), despite mounting evidence for comparable outcomes. This review aims to understand the outcomes following SOT, obstacles to SOT and opportunities to improve access and outcomes following SOT.
David W. J. Griffin, J. H. McMahon, D. A. Ruschena, J. F. Hoy   +3 more
wiley   +1 more source

Immunohistochemical detection of the latent nuclear antigen-1 of the human herpesvirus type 8 to differentiate cutaneous epidemic Kaposi sarcoma and its histological simulators Detecção imuno-histoquímica do antígeno nuclear latente-1 do herpesvirus tipo 8 para diferenciar o sarcoma de Kaposi epidêmico cutâneo de seus simuladores histológicos

Anais Brasileiros de Dermatologia, 2013
Kaposi's sarcoma is the most common neoplasia diagnosed in AIDS patients and the expression of the human herpesvirus-8 (HHV-8) latent nuclear antigen-1 has been useful for its histological diagnosis.
Patricia Fonseca Pereira, Tullia Cuzzi, Maria Clara Gutierrez Galhardo   +2 more
doaj  

Pseudosarcoma de Kaposi tipo Mali unilateral en paciente con insuficiencia venosa crónica

Revista Habanera de Ciencias Médicas, 2020
Introducción: La insuficiencia venosa crónica es el conjunto de síntomas y signos derivados de una hipertensión venosa en los miembros inferiores debido a un mal funcionamiento valvular de los sistemas venosos.
Mabel González Escudero, Dayrén Peraza Cruz, Lázaro Roque Pérez   +2 more
doaj  

Viral oncogene-induced DNA damage response is activated in Kaposi sarcoma tumorigenesis.

PLoS Pathogens, 2007
Kaposi sarcoma is a tumor consisting of Kaposi sarcoma herpesvirus (KSHV)-infected tumor cells that express endothelial cell (EC) markers and viral genes like v-cyclin, vFLIP, and LANA.
Sonja Koopal, Johanna H Furuhjelm, Annika Järviluoma, Sari Jäämaa, Pawan Pyakurel, Christel Pussinen, Maria Wirzenius, Peter Biberfeld, Kari Alitalo, Marikki Laiho, Päivi M Ojala   +10 more
doaj   +1 more source

Trends in Kaposi's sarcoma-associated Herpesvirus antibodies prior to the development of HIV-associated Kaposi's sarcoma: a nested case-control study. [PDF]

, 2014
HIV-associated Kaposi's sarcoma (KS) is a public health challenge in sub-Saharan Africa since both the causative agent, Kaposi's sarcoma associated-herpesvirus (KSHV), and the major risk factor, HIV, are prevalent. In a nested case-control study within a
Elliott, Alison M, Johnston, W Thomas, Mayanja, Billy N, Miley, Wendell, Nalwoga, Angela, Newton, Robert, Wakeham, Katie, Webb, Emily L, Whitby, Denise   +8 more
core   +1 more source

Cytokine biomarkers and their relationship to symptoms and quality of life in people with HIV‐associated Kaposi sarcoma

HIV Medicine, EarlyView.
Abstract Introduction Quality of life (QOL) is an essential component of care in people with HIV‐associated Kaposi sarcoma (HIV‐KS). Kaposi sarcoma herpes virus (KSHV) promotes cytokine expression and a dysfunctional inflammatory environment, contributing to KS pathogenesis and progression.
Fahmida Shaik, Thomas Smith Uldrick, Mikateko Mazinu, Nomonde Gwebushe, Anisa Mosam   +4 more
wiley   +1 more source

KSHV Genome Replication and Maintenance [PDF]

, 2016
Kaposi’s sarcoma associated herpesvirus (KSHV) or human herpesvirus 8 (HHV8) is a major etiological agent for multiple severe malignancies in immunocompromised patients.
Namrata Gupta, Pravinkumar Purushothaman, Prerna Dabral, Roni Sarkar, Subhash C. Verma   +4 more
core   +3 more sources

HIV: is it now a thing of the past?

Internal Medicine Journal, EarlyView.
Abstract Effective antiviral therapy for human immunodeficiency virus (HIV) has substantially reduced HIV‐associated morbidity and mortality for people living with HIV (PLWH). The use of antiviral therapies as prevention, most notably pre‐exposure prophylaxis (PrEP) as well as treatment as prevention (TasP), has significantly reduced the number of new ...
Jeffrey John Post
wiley   +1 more source