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Integrated transcriptomics unveils mitochondrial oxidative phosphorylation dysfunction as a shared mechanism in sarcopenia and obesity [PDF]
Scientific ReportsSarcopenia and obesity, two prevalent metabolic disorders in aging populations, often coexist and share overlapping pathophysiological mechanisms, yet the molecular mechanisms underlying their comorbidity remain elusive.
Ruixuan Yu +6 more
doaj +2 more sources
Journal of Cachexia, Sarcopenia and MuscleBackground Sarcopenia, the age‐related loss of muscle mass and function, brings multiple adverse outcomes including disability and death. Several sarcopenia consensuses have newly introduced the premorbid concept of possible sarcopenia and recommended ...
Ya‐Xi Luo +6 more
doaj +2 more sources
Using an electronic frailty index and patient reported outcomes to predict sarcopenia risk [PDF]
Scientific ReportsThe study goal was to identify sarcopenia using information from electronic health records (EHR) or prospectively collected patient reported outcomes tools among male and female adults participating in our Musculoskeletal Functioning, Imaging, and ...
Cody A. Altherr +6 more
doaj +2 more sources
Journal of Cachexia, Sarcopenia and Muscle, 2022 Background The association between sarcopenia and mild cognitive impairment (MCI) among elderly adults in China remains unclear. The present study aimed to examine the association based on a nationally representative large‐scale survey. Methods The study
Yisong Hu +4 more
doaj +2 more sources
Arquivos Brasileiros de Endocrinologia & Metabologia, 2014 Sarcopenia, the loss of muscle mass and function with age, is highly relevant to clinical practice as it has been associated with a wide range of ageing outcomes including disability and shorter survival times. As such it is now a major focus for research and drug discovery. There has been recent progress in the development of consensus definitions for
Dodds, R., Sayer, A.A.
openaire +8 more sources
Best Practice & Research Clinical Rheumatology, 2017 Sarcopenia is a condition that is characterized by loss of muscle mass, muscle strength and muscle functional impairment with ageing. The definition of sarcopenia has been through various permutations; however, an enormous recent breakthrough is the inclusion of the condition in the ICD-10 classification of diseases.
Fuggle, N. +3 more
openaire +5 more sources
Prevalence of characteristics associated with sarcopenia in elders: a cross-sectional study [PDF]
Revista Brasileira de Enfermagem, 2023 Objectives: to identify the prevalence and characteristics associated with sarcopenia in elders in Primary Health Care Units. Methods: cross-sectional study with 384 elders.
Caroline Ribeiro de Sousa +7 more
doaj +1 more source
The Role of Mitochondria in Mediation of Skeletal Muscle Repair
Muscles, 2023 Musculoskeletal health is directly linked to independence and longevity, but disease and aging impairs muscle mass and health. Complete repair after a pathological or physiological muscle injury is critical for maintaining muscle function, yet muscle ...
Stephen E. Alway +2 more
doaj +1 more source
Exercise for sarcopenia in older people: A systematic review and network meta‐analysis
Journal of Cachexia, Sarcopenia and Muscle, 2023 Sarcopenia is a serious public health concern among older adults worldwide. Exercise is the most common intervention for sarcopenia. This study aimed to compare the effectiveness of different exercise types for older adults with sarcopenia.
Yanjiao Shen +8 more
semanticscholar +1 more source
Sarcopenia and Cardiovascular Diseases
Circulation, 2023 Sarcopenia is the loss of muscle strength, mass, and function, which is often exacerbated by chronic comorbidities including cardiovascular diseases, chronic kidney disease, and cancer.
Abdulla A. Damluji +17 more
semanticscholar +1 more source