Results 141 to 150 of about 67,770 (262)

Sarcopenia, Cardiopulmonary Fitness, and Physical Disability in Community-Dwelling Elderly People [PDF]

, 2010
Meng‐Yueh Chien, Hsu‐Ko Kuo, Ying‐Tai Wu   +2 more
openalex   +1 more source

Multiple Pathways to the Same End: Mechanisms of Myonuclear Apoptosis in Sarcopenia of Aging [PDF]

, 2010
Emanuele Marzetti, Giuseppe Privitera, Vincenzo Simili, Stephanie E. Wohlgemuth, Lorenzo Aulisa, Marco Pahor, Christiaan Leeuwenburgh   +6 more
openalex   +1 more source

From Clinical to Benchside: Lacticaseibacillus and Faecalibacterium Are Positively Associated With Muscle Health and Alleviate Age‐Related Muscle Disorder

Aging Cell, EarlyView.
Old people with or without sarcopenia exhibited different gut microbiota and metabolite compositions. Mice receiving microbes from people with sarcopenia displayed lower muscle mass and strength compared with those receiving microbes from non‐sarcopenic donors.
Chaoran Liu, Pui Yan Wong, Nilakshi Barua, Baoqi Li, Hei Yuet Wong, Ning Zhang, Simon Kwoon Ho Chow, Sunny Hei Wong, Jun Yu, Margaret Ip, Wing Hoi Cheung, Gustavo Duque, Christoph Brochhausen, Joseph Jao Yiu Sung, Ronald Man Yeung Wong   +14 more
wiley   +1 more source

Low body mass index and sarcopenia associated with dose-limiting toxicity of sorafenib in patients with renal cell carcinoma [PDF]

, 2010
S. Antoun, Vickie E. Baracos, Laura Birdsell, Bernard Escudier, Michael B. Sawyer   +4 more
openalex   +1 more source

Circular RNA Telomerase Reverses Endothelial Senescence in Progeria

Aging Cell, EarlyView.
TERT circRNA outperforms linear TERT mRNA in reversing the hallmarks of senescence. TERT circRNA more efficiently restores endothelial function and shows superior capability in enhancing mitochondrial function. ABSTRACT Telomeres shorten with each cell division, acting as a chronometer of cell age. The enzyme telomerase, primarily active in stem cells,
Weifeng Qin, Kathrina D. Castillo, Hongye Li, Thi Kim Cuc Nguyen, Daniel L. Kiss, John P. Cooke, Anahita Mojiri   +6 more
wiley   +1 more source

Sarcopenia Accelerates at Advanced Ages in Fisher 344xBrown Norway Rats

, 2008
Entela B. Lushaj, Julene K. Johnson, Debbie McKenzie, Judd M. Aiken   +3 more
openalex   +1 more source

An overview of sarcopenia: facts and numbers on prevalence and clinical impact [PDF]

, 2010
Stephan von Haehling, John E. Morley, Stefan D. Anker   +2 more
openalex   +1 more source

The Mitochondria‐Targeted Peptide Therapeutic Elamipretide Improves Cardiac and Skeletal Muscle Function During Aging Without Detectable Changes in Tissue Epigenetic or Transcriptomic Age

Aging Cell, EarlyView.
The effects of the mitochondria‐targeted peptide therapeutic elamipretide on age‐related muscle function were compared with its effects on molecular biomarkers of aging. It was found that elamipretide treatment partially reverses age‐related cardiac dysfunction and skeletal muscle weakness in mice without significantly affecting muscle epigenetic or ...
Wayne Mitchell, Gavin Pharaoh, Alexander Tyshkovskiy, Matthew Campbell, David J. Marcinek, Vadim N. Gladyshev   +5 more
wiley   +1 more source

Nutritional Recommendations for the Management of Sarcopenia [PDF]

, 2010
John E. Morley, Josep M. Argilés, William J. Evans, Shalender Bhasin, David Cella, Nicolaas E.P. Deutz, Wolfram Doehner, Ken Fearon, Luigi Ferrucci, Marc K. Hellerstein, Kamyar Kalantar‐Zadeh, Herbert Lochs, Neil Macdonald, Kathleen Mulligan, Maurizio Muscaritoli, Piotr Ponikowski, Mary Ellen Posthauer, Filippo Rossi Fanelli, Morrie Schambelan, Annemie M.W.J. Schols, Michael W. Schuster, Stefan D. Anker   +21 more
openalex   +1 more source

Effects of the VIVIFRAIL Exercise Protocol on Circulatory and Intracellular Peripheral Mediators Bridging Mitochondrial Dynamics and Inflammation in Robust and Frail Older People

Aging Cell, EarlyView.
Physical activity promotes functional improvements in both robust and physically frail older adults, driven by distinct adaptation mechanisms in the mitochondria‐inflammation axis that are influenced by age and frailty status. ABSTRACT Physical exercise has been associated with healthier aging trajectories, potentially preventing or mitigating age ...
Fiona Limanaqi, Evelyn Ferri, Pasquale Ogno, Franca Rosa Guerini, Gabriela Alexandra Mihali, Tiziano Lucchi, Mario Clerici, Chiara Fenoglio, Laura D'Andrea, Elena Marcello, Mara Biasin, Beatrice Arosio   +11 more
wiley   +1 more source