Results 151 to 160 of about 129,284 (273)

Exercise, exerkines, and muscle–brain crosstalk in Parkinson's disease

open access: yesNeuroprotection, EarlyView.
Abstract Parkinson's disease (PD) is a progressive neurodegenerative disorder with motor and non‐motor symptoms, driven by dopaminergic loss and α‐synuclein accumulation. Beyond neurodegeneration, growing evidence highlights skeletal muscle health as a key determinant of prognosis, with sarcopenia and frailty contributing to greater disability, fall ...
Salomón Páez‐García   +7 more
wiley   +1 more source

Safety and Efficacy of Glucagon‐Like Peptide‐1 Receptor Agonists Use in Elderly People With Obesity—A Meta‐Analysis

open access: yesObesity, EarlyView.
ABSTRACT Objective This meta‐analysis evaluates the safety and efficacy of glucagon‐like peptide‐1 receptor agonists (GLP‐1 RA) for the treatment of older adults with obesity compared to younger individuals. Methods A systematic review was conducted following PRISMA guidelines (PROSPERO CRD420251074381).
Inês Rego de Figueiredo   +4 more
wiley   +1 more source

Sarcopenia

open access: yesAnnals of Physical and Rehabilitation Medicine, 2012
Gordon S. Lynch   +22 more
  +4 more sources

Sarcopenia Risk is Associated With Decreased Swallow Safety in Patients With Dysphagia

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Sarcopenia, characterized by the loss of skeletal muscle mass and strength, is associated with adverse health outcomes in older adults. This study aimed to evaluate the relationship between sarcopenia risk, handgrip strength, and swallowing function in patients with dysphagia undergoing Fiberoptic Endoscopic Evaluation of Swallowing (
Nogah Nativ‐Zeltzer   +7 more
wiley   +1 more source

Fast Quantitative Evaluation of the Amelioration Effect in MASLD During Semaglutide Treatment Using Ultrasound‐Derived Fat Fraction and Fat‐to‐Muscle Ratio

open access: yesPortal Hypertension &Cirrhosis, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) is a chronic liver disease. Research into a feasible, rapid, and effective assessment method is crucial for evaluating the therapeutic effects of semaglutide in MASLD. This prospective study utilized ultrasound‐derived fat fraction measurement and fat‐to‐muscle ratio to evaluate hepatic ...
Yunlin Huang   +10 more
wiley   +1 more source

Chinese Registry on Transjugular Intrahepatic Portosystemic Shunts (CN‐TIPS): Protocol for a Registry‐Based, Prospective Prognostic Study

open access: yesPortal Hypertension &Cirrhosis, EarlyView.
CN‐TIPS is a nationwide, multicenter prospective registry that will enroll 10,000 adults with portal hypertension undergoing transjugular intrahepatic portosystemic shunt in China, integrating perioperative clinical and hemodynamic metrics with standardized imaging (including computational modeling in a dedicated subcohort) and multi‐omics biospecimens,
Yi Xiang   +20 more
wiley   +1 more source

Body Composition and Muscle Function in Bronchiectasis: A Comparative Longitudinal Study

open access: yesRespirology, EarlyView.
We compared body composition and muscle function in adults with bronchiectasis versus controls and assessed if leg strength estimates 1‐year outcomes. Patients with bronchiectasis had lower muscle mass, bone density, and leg strength. Reduced leg strength is associated with worse dyspnoea, quality of life, and functional capacity, highlighting the need
Joice Mara de Oliveira   +7 more
wiley   +1 more source

Mapping of Preoperative Screening Tools Reveals Urgent Need for Standardization in Gastrointestinal Cancer Surgery: A Scoping Review

open access: yesWorld Journal of Surgery, EarlyView.
Although most screening tools are brief, feasible for self‐administration, and freely accessible, none integrated all three domains. Substantial heterogeneity in tools highlights the need for a comprehensive, validated multidomain preoperative screening tool for this population.
Alexandria Paige Petridis   +17 more
wiley   +1 more source

Amino Acid Kinetics and the Response to Nutrition in Patients with Cancer [PDF]

open access: yes, 2019
Deutz, Nicolaas Ep   +3 more
core   +1 more source

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