Results 181 to 190 of about 129,284 (273)

Risk of Sarcopenia, Anxiety and Depression Among Healthcare Professionals in Disability Care Facilities. [PDF]

J Frailty Sarcopenia Falls
Kolovou A, Matzaroglou C, Stefanou N, Tsekoura M, Vlychou M, Gkougkoulias AN, Dailiana ZH.   +6 more
europepmc   +1 more source

LCN2‐ACOD1 Signalling Affects the Post‐Injury Regeneration of Skeletal Muscle Through Mediating Ferroptosis

Cell Proliferation, EarlyView.
LCN2 mediates the suppression of C2C12 myoblast proliferation and myotube formation via erastin‐induced ferroptosis. Mechanistically, the LCN2‐ACOD1 axis regulates skeletal muscle growth via mitochondria‐associated ferroptosis, providing a theoretical basis for the prevention and therapy of muscle‐related diseases.
Xiaojing Hao, Hongwei Shi, Di Wu, Rui Liang, Tong Zhao, Wen Sun, Yue Wang, Xiuju Yu, Xiaomao Luo, Yi Yan, Jiayin Lu, Haidong Wang, Juan Wang   +12 more
wiley   +1 more source

Association between SARC-F as a self-report screening tool for sarcopenia and muscle strength, physical performance, daily activity, patient-reported outcomes and body composition in patients with spondyloarthritis. [PDF]

RMD Open
Kononenko J, Bedei M, Buehring B, Kiefer D, Redeker I, Baraliakos X, Kiltz U.   +6 more
europepmc   +1 more source

Hepatic and abdominal adiposity in type 2 diabetes as assessed with machine learning on computed tomography scans

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims The combined assessment of multiple abdominal imaging traits in relation to type 2 diabetes remains incompletely characterised. The study examines these relationships on computed tomography (CT) scans from a large‐scale, racially diverse, disease‐focused medical biobank.
Richard H. Tran, Pavan Raghupathy, Mohamad Hazim, Elizabeth Thompson, Sophia Swago, Abhijit Bhattaru, Matthew MacLean, Jeffrey T. Duda, James Gee, Charles Kahn Jr., Daniel J. Rader, Arijitt Borthakur, Walter R. Witschey, Hersh Sagreiya   +13 more
wiley   +1 more source

Diagnostic Performance of Four Screening Tools for Detecting Low Muscle Mass and Sarcopenia in Preoperative Older Japanese Patients with Colorectal Cancer According to the AWGS 2019 Criteria. [PDF]

J Frailty Sarcopenia Falls
Shimamura Y, Akazawa N, Nakajima S, Kobayashi Y, Aoi W, Kuwahata M.   +5 more
europepmc   +1 more source

Growth differentiation factor 15 mitigates lipotoxic steatosis by preserving mitochondrial morphodynamics and augmenting fatty acid oxidation in hepatocytes and liver organoids

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Growth differentiation factor 15 (GDF15) has emerged as a promising metabolic regulator with hepatoprotective properties in metabolic dysfunction‐associated steatotic liver disease (MASLD), yet its underlying mechanisms remain elusive.
Jia Li, Qi Zhou, Mengmeng Xia, Yakun Li, Junyu Wang, Manon Buist‐Homan, Vincent E. de Meijer, Hans Blokzijl, Klaas Nico Faber, Han Moshage   +9 more
wiley   +1 more source

SARC-T a new physical test for sarcopenia assessment with development, validation and physiological evaluation. [PDF]

Front Aging
Pedauyé-Rueda B, Maté-Muñoz JL, Hernández-Lougedo J, Aparicio-García I, Cerrolaza-Tudanca S, Rozalén-Bustín M, Rodríguez-Moreno I, García-Fernández P.   +7 more
europepmc   +1 more source

Intravenous Oxytocin Has no Effect on Ad Libitum Food Intake or Postprandial Plasma Glucose Concentrations in Individuals With Obesity: A Randomised, Placebo‐Controlled, Double‐Blind, Crossover Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Introduction Oxytocin is expressed throughout the small intestine, suggesting a role for oxytocin in postprandial metabolism. Accordingly, single‐dose intranasal oxytocin reduces food intake and improves glucose tolerance. We investigated the effects of a continuous intravenous oxytocin infusion on ad libitum food intake, appetite sensations ...
Ida M. Gether, Vivian Kliim‐Hansen, Petur T. Olafsson, Miriam G. Pedersen, Casper K. Nielsen, Anne‐Marie Ellegaard, Mikkel B. Christensen, Jens F. Rehfeld, Jørn W. Helge, Jens J. Holst, Bolette Hartmann, Filip K. Knop, Lærke S. Gasbjerg, Asger B. Lund   +13 more
wiley   +1 more source

Sarcopenia as a risk factor for incident pain in Chinese middle-aged and older adults: longitudinal evidence from the CHARLS cohort. [PDF]

J Nutr Health Aging
Zhang X, Li X, Li H, Xiao Z, Qu R, Zhou J.   +5 more
europepmc   +1 more source

Resistance‐exercise‐induced stress intervenes in TGF‐β signaling by cooperatively downregulating nuclear αB‐crystallin and SMAD4 in human skeletal muscle fibers

The FEBS Journal, EarlyView.
Alpha‐crystallin B chain (CRYAB) has been reported to stabilize mothers against decapentaplegic homolog 4 (SMAD4) in transforming growth factor‐β (TGF‐β) signaling, enabling target gene transcription. We show nuclear CRYAB–SMAD4 interaction for the first time in human skeletal muscle fibers and its regulation by exercise.
Kirill Schaaf, Cassandra Duda, Tihomir Kostov, Patrick Diel, Käthe Bersiner, Wilhelm Bloch, Sebastian Gehlert, Daniel Jacko   +7 more
wiley   +1 more source