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Sarcopenia is a condition that is characterized by loss of muscle mass, muscle strength and muscle functional impairment with ageing. The definition of sarcopenia has been through various permutations; however, an enormous recent breakthrough is the inclusion of the condition in the ICD-10 classification of diseases.
Fuggle, N. +3 more
+9 more sources
Sarcopenia is a progressive and generalised skeletal muscle disorder involving the accelerated loss of muscle mass and function that is associated with increased adverse outcomes including falls, functional decline, frailty, and mortality. It occurs commonly as an age-related process in older people, influenced not only by contemporaneous risk factors,
Cruz-Jentoft AJ, Sayer AA
+10 more sources
Sarcopenia, the loss of muscle mass and function with age, is highly relevant to clinical practice as it has been associated with a wide range of ageing outcomes including disability and shorter survival times. As such it is now a major focus for research and drug discovery. There has been recent progress in the development of consensus definitions for
Alfonso J, Cruz-Jentoft +1 more
openaire +8 more sources
Sarcopenia is the accelerated loss of skeletal muscle mass and function commonly, but not exclusively, associated with advancing age. It is observed across many species including humans in whom it can lead to decline in physical function and mobility as well as to increased risk of adverse outcomes including falls, fractures and premature mortality ...
Avan A. Sayer +8 more
+11 more sources
"Uremic sarcopenia" refers to a progressive decrease in muscle mass, strength, and function despite normal skeletal muscle physiology in patients with chronic kidney disease (CKD). Sarcopenia involves multiple risk factors, comprising immunological changes, hormonal, metabolic acidosis, reduced protein intake, and physical inactivity.
Mohanasundaram, Subashri +1 more
openaire +2 more sources
Sarcopenia is a very common, but frequently overlooked and undertreated geriatric syndrome comprising pronounced muscle mass and strength/performance loss. Estimated prevalence is between 5 and 40% in the general population, accompanied by an exponential incline with increasing age. Sarcopenia is connected to atrophy and loss of muscle fibers and motor
Cruz-jentoft, Alfonso J. +28 more
+7 more sources
Sarcopenia as a Robust Predictor of Readmission within 6 Months among Individuals Experiencing Acute Stroke [PDF]
Background Sarcopenia negatively affects the short-term prognosis of hospitalized older adults. However, no evidence currently supports a direct relationship between sarcopenia and readmission among individuals who have experienced an acute stroke ...
Takafumi Abe +4 more
doaj +1 more source
Sarcopenic obesity and risk of cardiovascular disease and mortality: a population-based cohort study of older men. [PDF]
OBJECTIVES: To examine associations between sarcopenia, obesity, and sarcopenic obesity and risk of cardiovascular disease (CVD) and all-cause mortality in older men. DESIGN: Prospective cohort study.
Atkins, JL +5 more
core +1 more source
Maximal voluntary force (strength) production declines with age and contributes to physical dependence and mortality. Consequently, a great deal of research has focused on identifying strategies to maintain muscle mass during the aging process and elucidating key molecular pathways of atrophy, with the rationale that the loss of strength is primarily a
Brian C, Clark, Todd M, Manini
openaire +2 more sources
Sarcopenic Obesity Defined by Japanese Working Group on Sarcopenic Obesity in Post-Stroke Inpatients: Prevalence and Clinical Implications [PDF]
Background Sarcopenic obesity (SO) is characterized by the coexistence of sarcopenia and obesity, associated with adverse health outcomes. This study aimed to investigate the prevalence of SO as defined by the recently published Japanese Working Group on
Ayaka Matsumoto +10 more
doaj +1 more source

