Results 231 to 240 of about 88,763 (308)

Microgravity‐induced changes in skeletal muscle and possible countermeasures: What we can learn from bed rest and human space studies

Experimental Physiology, EarlyView.
Abstract Despite exercise countermeasures to sustain health and performance in spaceflight, complete maintenance of muscle mass and functions in microgravity is still not possible for most astronauts. The principal cause of the limited effectiveness of existing exercise countermeasures is the difficulty in achieving full loading forces in space.
Alessandra Bosutti, Bergita Ganse, Nicola A. Maffiuletti, Rob C. I. Wüst, Gustav J. Strijkers, Andy Sanderson, Hans Degens   +6 more
wiley   +1 more source

Causal Links Between Sleep Duration and Sarcopenia-Related Phenotypes: A Mendelian Randomization and Shared Genetic Mechanism Study. [PDF]

Am J Phys Med Rehabil
Shang H, Deng Z, Lian Y, Ai Y, Zhang J, Li G.   +5 more
europepmc   +1 more source

Turning over new ideas in human skeletal muscle proteostasis: What do we know and where to from here?

Experimental Physiology, EarlyView.
Abstract Understanding the turnover of proteins in tissues gives information as to how external stimuli result in phenotypic change. Nowhere is such phenotypic change more conspicuous than skeletal muscle, which can be effectively remodelled by increased loading, ageing and unloading (disuse), all of which are subject to modification by nutrition and ...
Changhyun Lim, James McKendry, Matthew Lees, Philip J. Atherton, Nicholas A. Burd, Andrew M. Holwerda, Luc J. C. van Loon, Chris McGlory, Cameron J. Mitchell, Kenneth Smith, Daniel J. Wilkinson, Tanner Stokes, Stuart M. Phillips   +12 more
wiley   +1 more source

Association of sarcopenia, sarcopenic obesity with incident dementia, cognitive functions, and brain structure: findings from the UK Biobank Study. [PDF]

J Nutr Health Aging
Zhang X, Han W, Li Y, Yang P, Jia Y, Sun L, Wang R, Shi M, Zheng X, Zhang Y, Zhu Z.   +10 more
europepmc   +1 more source

Redox‐regulated signalling of adaptations to contractile activity in skeletal muscle: Implications for age‐related muscle weakness

Experimental Physiology, EarlyView.
Abstract Skeletal muscle adaptation to contractile activity is modulated by redox signalling, primarily through reactive oxygen species (ROS) such as hydrogen peroxide (H2O2). Early research framed ROS as deleterious byproducts of exercise, but subsequent studies have established their roles as signalling molecules involved in mitochondrial biogenesis,
Malcolm J. Jackson
wiley   +1 more source

Association of baseline and cumulative CHG index with risk of new-onset sarcopenia in middle-aged and older adults. [PDF]

J Nutr Health Aging
Chen Y, Gao L, Gao J, Feng X.
europepmc   +1 more source

Muscle wasting in cancer cachexia: Mechanisms and the role of exercise

Experimental Physiology, EarlyView.
Abstract Cancer cachexia (CC) is a multifactorial disease marked by a severe and progressive loss of lean muscle mass and characterized further by inflammation and a negative energy/protein balance, ultimately leading to muscle atrophy and loss of muscle tissue.
Zoe P. Libramento, Louisa Tichy, Traci L. Parry   +2 more
wiley   +1 more source

Circulating biomarkers in older adults with and without sarcopenia: a systematic review and meta-analysis. [PDF]

J Gerontol A Biol Sci Med Sci
Prokopidis K, Deane CS, Baoubbou Z, Beaudart C.   +3 more
europepmc   +1 more source

Triglyceride-Glucose-Waist-to-Weight Index: Novel Biomarker for Mild Cognitive Impairment in Older People With Sarcopenic Obesity. [PDF]

J Cachexia Sarcopenia Muscle
Xing Y, Liu Q, He X, Ma L, Song Y, PhD NC.   +5 more
europepmc   +1 more source