Results 41 to 50 of about 67,770 (262)

MyoSuite -- A contact-rich simulation suite for musculoskeletal motor control [PDF]

arXiv, 2022
Embodied agents in continuous control domains have had limited exposure to tasks allowing to explore musculoskeletal properties that enable agile and nimble behaviors in biological beings. The sophistication behind neuro-musculoskeletal control can pose new challenges for the motor learning community.
arxiv  

Autocrine GDF10 Inhibits Hepatic Stellate Cell Activation via BMPR2/ALK3 Receptor to Prevent Liver Fibrosis

Advanced Science, EarlyView.
Liver fibrosis is a growing global health burden with no specific treatment. HSC activation is the predominant driver of liver fibrogenesis and the current focus in antifibrotic drug discovery. This study identifies autocrine GDF10 activates BMPR2/ALK3‐SMAD1/5/8‐SMAD7 pathway to counteract the TGF‐β‐SMAD2/3 pathway in HSCs, thereby inhibiting HSC ...
Yinliang Zhang, Xiaochen Gai, Yuhui Li, Zuoyu Chen, Xi Zhang, Wei Qiao, Ping Qiu, Chunyuan Du, Sufang Sheng, Jingran Hao, Yujie Zhang, Heng Fan, Xiaorong Li, Ming Liu, Jun Zhang, Zhe Pan, Yongsheng Chang   +16 more
wiley   +1 more source

Fully-automated deep learning slice-based muscle estimation from CT images for sarcopenia assessment [PDF]

arXiv, 2020
Objective: To demonstrate the effectiveness of using a deep learning-based approach for a fully automated slice-based measurement of muscle mass for assessing sarcopenia on CT scans of the abdomen without any case exclusion criteria. Materials and Methods: This retrospective study was conducted using a collection of public and privately available CT ...
arxiv  

Nutrition education with or without oral nutrition supplements has contrasting effects on nutrition status in older adults: A randomized controlled study

Nutrition in Clinical Practice, Volume 38, Issue 1, Page 138-147, February 2023., 2023
Abstract Background Oral nutrition supplements (ONSs) play an important role in the management of malnutrition. This aim of study was to examine whether a comprehensive intervention, combining ONSs, family‐centered health education, and nutrition and medical consultations, could improve the nutrition and health status of malnourished older adults ...
Hua Xie, Li Hua Qiao, Yue Zhao, Zijie Yan, Huijin Bai, Yan Wang, Tingting Ye, Jun Yu, Qin Du, Jianqin Sun   +9 more
wiley   +1 more source

A continuum model of skeletal muscle tissue with loss of activation [PDF]

, 2017
We present a continuum model for the mechanical behavior of the skeletal muscle tissue when its functionality is reduced due to aging. The loss of ability of activating is typical of the geriatric syndrome called sarcopenia. The material is described by a hyperelastic, polyconvex, transverse isotropic strain energy function.
arxiv   +1 more source

MSKdeX: Musculoskeletal (MSK) decomposition from an X-ray image for fine-grained estimation of lean muscle mass and muscle volume [PDF]

arXiv, 2023
Musculoskeletal diseases such as sarcopenia and osteoporosis are major obstacles to health during aging. Although dual-energy X-ray absorptiometry (DXA) and computed tomography (CT) can be used to evaluate musculoskeletal conditions, frequent monitoring is difficult due to the cost and accessibility (as well as high radiation exposure in the case of CT)
arxiv  

Twelve‐year sarcopenia trajectories in older adults: results from a population‐based study

Journal of Cachexia, Sarcopenia and Muscle, 2022
Background The dynamic nature of sarcopenia, including possible transitions between its different stages, is currently unknown. We aimed to explore 12 year transitions through sarcopenia stages and identify factors associated with different sarcopenia ...
Caterina Trevisan, Davide Liborio Vetrano, Riccardo Calvani, Anna Picca, Anna‐Karin Welmer   +4 more
doaj   +1 more source

Frontiers in Nondrug Treatment of Sarcopenia: A Review of Pathological Mechanisms and the Latest Treatment Strategies

AGING MEDICINE, EarlyView.
This article mainly introduces the pathologic process of sarcopenia and the recent progress in diagnosis and treatment, especially the nondrug treatment. ABSTRACT Sarcopenia refers to the progressive decline and wasting of skeletal muscle function, typically linked to aging or as a secondary effect of various conditions, including systemic inflammation,
Qi‐Fei Kuang, Yu‐Qing Ni, You‐Shuo Liu   +2 more
wiley   +1 more source

Longitudinal changes in sarcopenia was associated with survival among cirrhotic patients

Frontiers in Nutrition
BackgroundSarcopenia is common in patients with liver cirrhosis and is an independent predictor of multiple clinical outcomes. Most studies to date have used a static assessment of sarcopenia.
Minjie Jiang, Minjie Jiang, Xin Hua, Muchen Wu, Jing Wu, Xiaotong Xu, Juan Li, Qinghua Meng   +7 more
doaj   +1 more source

The association between sarcopenia and incident chronic lung disease in the general population: A longitudinal study based on CHARLS data

Experimental Gerontology, 2023
Background: Data regarding the association of sarcopenia with chronic lung disease (CLD) has led to inconclusive results. The main goal of this research was to investigate the association between sarcopenia and CLD in middle-aged and elderly individuals ...
Hongxiang Wang, Hongbin Qiu, Xia Gu, Yiying Zhang, Shanjie Wang   +4 more
doaj