Results 61 to 70 of about 105,256 (302)

The role of myostatin during postnatal myogenesis and sarcopenia [PDF]

, 2007
Myostatin, a TGF-β superfamily member, is a key negative regulator of embryonic and postnatal muscle growth. In order to further elucidate the role of myostatin during postnatal growth, several lines of investigation were undertaken in mice.
Siriett, Victoria Katherine
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Rheumatoid Arthritis, Frailty, and Outcomes of Surgical Hospitalizations: A National Population‐Based Analysis

Arthritis Care &Research, EarlyView.
Objective Hospitalization, particularly for surgery, represents a period of heightened stress. We evaluated how frailty attenuates the association of rheumatoid arthritis (RA) with negative health outcomes after elective noncardiac surgery. Methods We conducted a cross‐sectional study using the National Inpatient Sample (2018 to 2020), including adults
Ali Yazdanyar, Joshua Baker, Katherine D. Wysham, Mohammed Yousufuddin, Farah Acher Kaiksow, Michael M. Ward   +5 more
wiley   +1 more source

Effectiveness of different resistance training modalities in sarcopenia: a literature review

, 2022
reservedLa speranza di vita è in continuo aumento e gli anziani costituiscono una percentuale sempre più elevata dell’intera popolazione. Il rischio di sarcopenia, ovvero la perdita degenerativa di massa, forza muscolare e performance fisica, aumenta ...
DE BIASI, NICOLO'
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Loss of LCN2 Function Ameliorates Glucocorticoid‐Induced Muscle Atrophy via Remodeling the Extracellular Matrix

Advanced Science, EarlyView.
Glucocorticoids transcriptionally activate LCN2 expression via GR nuclear translocation. Secreted LCN2 binds MMP9 to degrade skeletal muscle ECM collagen, blocks integrin‐mediated mechanotransduction, bidirectionally disrupts muscle protein homeostasis, and reveals a novel target for steroid‐induced muscle atrophy.
Hongwei Shi, Xiaojing Hao, Yi Yan, Fengyang Li, Yaru Zhang, Zixin Li, Wenjuan Xie, Jiayin Lu, Xiaomao Luo, Yanjun Dong, Haidong Wang, Juan Wang   +11 more
wiley   +1 more source

The Relationship of Sleep Duration with Obesity and Sarcopenia in Community-Dwelling Older Adults

, 2017
Background: Numerous studies have reported the relationship between sleep duration and obesity in elderly adults; however, little is known about the relationship of sleep duration and sarcopenia.
王儷穎;簡盟月;陳錫中, Chien, Meng-Yueh;Wang, Li-Ying;Chen, Hsi-Chung   +1 more
core   +1 more source

Single‐Nucleus Atlas of Spinal Sarcopenia Patients Reveals Disruption of Quiescent and Regenerative Satellite Cell Niches in Fatty‐Infiltrated Muscle

Advanced Science, EarlyView.
Mechanisms of Fatty Infiltration and Muscle Degeneration. Clinical metadata identified intramuscular fat accumulation as an independent driver of muscle mass decline. Single‐nucleus RNA sequencing of spinal sarcopenia muscle revealed adipogenic reprogramming of fibro‐adipogenic progenitors, satellite‐cell niche disruption, and elevated levels of the ...
Wenkai Wu, Renxian Wang, Dingding Wang, Quanzhong Ren, Ling Wang, Fangfang Duan, Guihe Yang, Ruixuan Yu, Yi Wang, Yingyu Zhang, Zetong Zang, Chuqi Li, Weijia Liu, Wenshuang Zhang, Yi Yuan, Zitong Cheng, Xiaoguang Cheng, Junbo Liang, Yajun Liu   +18 more
wiley   +1 more source

Nutritional recommendations for the management of sarcopenia [PDF]

, 2010
The Society for Sarcopenia, Cachexia, and Wasting Disease convened an expert panel to develop nutritional recommendations for prevention and management of sarcopenia.
Argiles, J.M., John E. Morley, William J. Evans, Fearon, Ken CH, Nicolaas E.P. Deutz, MacDonald, Neil, Nicolaas E. P. Deutz, Wolfram Doehner, Hellerstein, Marc K, Deutz, Nicolaas EP, Ferrucci, L., Schols, A.M.W.J., Anker, S.D., Fearon, K.C., Evans, William J, Schambelan, Morrie, Josep M. Argiles, Maurizio Muscaritoli, Morley, J.E., Cella, David, Ponikowski, P., Filippo Rossi Fanelli, Bhasin, S., Shalender Bhasin, ROSSI FANELLI, Filippo, Wasting Disease, Deutz, N.E., Argiles, Josep M, MacDonald, N., Ponikowski, Piotr, David Cella, Marc K. Hellerstein, Muscaritoli, M., Michael W. Schuster, Mulligan, Kathleen, Society For Sarcopenia, Schambelan, M., Mary Ellen Posthauer, Herbert Lochs, Mulligan, K., Bhasin, Shalender, Kathleen Mulligan, Lochs, Herbert, Luigi Ferrucci, Annemie M.W.J. Schols, Anker, Stefan D, Morley, John E, Doehner, W., Kamyar Kalantar-Zadeh, Kamyar Kalantar Zadeh, Neil Macdonald, Schols, Annemie MWJ, MUSCARITOLI, Maurizio, Ken C.H. Fearon, Stefan D. Anker, Morrie Schambelan, Lochs, H., Doehner, Wolfram, Annemie M. W. J. Schols, Posthauer, Mary Ellen, Evans, W.J., Ferrucci, Luigi, Kalantar Zadeh, K., Kalantar-Zadeh, Kamyar, Cachexia, Cella, D., Schuster, M.W., Ken C. H. Fearon, Piotr Ponikowski, Rossi Fanelli, F., Posthauer, M.E., Fanelli, Filippo Rossi, Schuster, Michael W, Hellerstein, M.K., The Society for Sarcopenia, Cachexia   +74 more
core   +1 more source

Nuclear Translocation of PFKFB3 Promotes Disuse‐Induced Muscle Atrophy via Scaffolding Nedd4‐Mediated JunB Ubiquitination

Advanced Science, EarlyView.
Disuse‐induced muscle atrophy is driven by a non‐metabolic, nuclear function of the enzyme PFKFB3. Acting as a scaffold, PFKFB3 facilitates Nedd4‐mediated ubiquitination and degradation of the anti‐atrophy transcription factor JunB. Inhibiting this novel PFKFB3–Nedd4–JunB signaling axis stabilizes JunB and alleviates muscle wasting, revealing a highly ...
Mengjun Ma, Yinliang Liu, Wangchang Wu, Biao Yang, Jiahao Zhuang, Haoye Yu, Rujia Mi, Yixuan Lu, Wen Yang, Hanting Yi, Chenglong Yuan, Yinfeng Gu, Hongyu Li   +12 more
wiley   +1 more source

Factors That Improve Chest Computed Tomography-Defined Sarcopenia Prognosis in Advanced Non-Small Cell Lung Cancer

Frontiers in Oncology, 2021
BackgroundWhether muscle strength and physical performance should be components of sarcopenia remains controversial. This study evaluated the skeletal muscle index derived from computed tomography images at the 12th thoracic vertebra level (T12 SMI ...
Ming Yang, Ming Yang, Ming Yang, Lingling Tan, Lingling Xie, Song Hu, Dan Liu, Jing Wang, Weimin Li, Weimin Li, Weimin Li   +10 more
doaj   +1 more source

EFFECTS OF LEUCINE SUPPLEMENTATION AND RESISTANCE TRAINING TO COUNTERACT SARCOPENIA

, 2022
openLa sarcopenia, ossia la diminuzione di forza e/o massa muscolare che si verifica con l’invecchiamento, rappresenta una realtà sempre più frequente tra le classi anziane e di interesse per i sistemi sanitari.
TOMMASINI, ENRICO
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