Results 61 to 70 of about 131,783 (290)

Frailty is independently associated with increased hospitalisation days in patients on the liver transplant waitlist [PDF]

, 2016
AIM: To investigate the impact of physical frailty on risk of hospitalisation in cirrhotic patients on the liver transplant waitlist. METHODS: Cirrhotics listed for liver transplantation at a single centre underwent frailty assessments using the Fried ...
Dodge, Jennifer L, Lai, Jennifer C, Poltayskiy, Eduard, Sinclair, Marie   +3 more
core   +1 more source

Effect of allopurinol on phosphocreatine recovery and muscle function in older people with impaired physical function:a randomised controlled trial [PDF]

, 2020
Background: Allopurinol has vascular antioxidant effects and participates in purinergic signalling within muscle. We tested whether allopurinol could improve skeletal muscle energetics and physical function in older people with impaired physical ...
Cavin, Ian, Clarke, Clare L., Gandy, Stephen, George, Jacob, Gingles, Christopher, Hutcheon, Anita, Nicholas, Richard S., Priba, Lukasz, Struthers, Allan D., Sumukadas, Deepa, Witham, Miles D.   +10 more
core   +2 more sources

Pain and Patient‐Reported Physical Function Did Not Differ Among Body Composition Profiles in Patients With Hip Osteoarthritis

Arthritis Care &Research, EarlyView.
Objective To explore whether higher body fat and lower lean mass are associated with greater pain and worse patient‐reported physical function in individuals with hip osteoarthritis (OA). A secondary aim was to examine whether pain and patient‐reported physical function differ according to four body composition profiles: high body fat, low lean mass ...
Alexandra Ryan, Boliang Wang, Fiona Dobson, Ben Kirk, Travis Haber, Kim L. Bennell, Shirley P. Yu, Kim Allison, Ricardo J. S. Costa, Gabrielle Knox, Michelle Hall   +10 more
wiley   +1 more source

Obesity subtypes and longitudinal trajectories of function over 7‐years of follow‐up: data from the Multicenter Osteoarthritis Study

Arthritis Care &Research, Accepted Article.
Background Obesity, defined by BMI ≥30kg/m2, is a risk factor for functional limitations in people with knee osteoarthritis (OA). However, function varies among such individuals. Our objective was to evaluate the implications of obesity subtypes on longitudinal patterns of physical functioning in people with or at risk for knee OA.
Kristine Godziuk, Sarah Tilley, Michael LaValley, Michael C. Nevitt, Cora E. Lewis, James C. Torner, Tuhina Neogi   +6 more
wiley   +1 more source

Longitudinal changes in sarcopenia was associated with survival among cirrhotic patients

Frontiers in Nutrition
BackgroundSarcopenia is common in patients with liver cirrhosis and is an independent predictor of multiple clinical outcomes. Most studies to date have used a static assessment of sarcopenia.
Minjie Jiang, Minjie Jiang, Xin Hua, Muchen Wu, Jing Wu, Xiaotong Xu, Juan Li, Qinghua Meng   +7 more
doaj   +1 more source

Prevalence of sarcopenia and sarcopenic obesity in Korean adults: The Korean Sarcopenic Obesity Study (KSOS) [PDF]

, 2009
*Context:* Sarcopenic obesity (SO), a combination of excess weight and reduced muscle mass and/or strength, is suggested to be associated with an increased risk of adverse health outcomes.
Dong Seop Choi, Hye Jin Yoo, Hyun Joo Kang, Ji A Seo, Kang Il Lim, Kyung Mook Choi, Nan Hee Kim, Sae Jeong Yang, Sei Hyun Baik, Sin Gon Kim, Tae Nyun Kim, Wook Song   +11 more
core   +1 more source

Systemic inflammation, body composition, and physical performance in old community-dwellers [PDF]

, 2017
Background Chronic inflammation, changes in body composition, and declining physical function are hallmarks of the ageing process. The aim of the present study was to provide a preliminary characterisation of the relationship among these age-related ...
Addison, Addison, Bandeen-Roche, Buford, Calvani, Cesari, De Martinis, Deng, Dong, Franceschi, Goodpaster, Guralnik, Haehling, Hsu, Hughes, Hughes, Jiang, Jo, Lau, Liao, Marzetti, Marzetti, Marzetti, Opal, Peterson, Prokopchuk, Roubenoff, Seals, Szymańska, Tuttle, Varadhan, Westerhuis, Westerhuis, Zoico   +33 more
core   +2 more sources

Nicotinamide and Pyridoxine Supplementation Enhances Muscle Stem Cell Activity and Muscle Regeneration in Humans: A Randomized Placebo‐Controlled Clinical Trial of High Force Eccentric Contraction Recovery in Healthy Young Men

Advanced Science, EarlyView.
In a randomized clinical trial, we test the potential of combined nicotinamide (NAM) and pyridoxine (PN) to improve muscle recovery through muscle stem cell (MuSC) activity. Daily oral NAM and PN supplementation after high intensity muscle contractions enhances MuSC activation and differentiation, and accelerates muscle regeneration, providing new ...
Grith Højfeldt, Joris Michaud, Ann Damgaard, Karoline Karlog, Eugenia Migliavacca, Sonia Karaz, Elham Pazirandeh‐Micol, Odd E. Johansen, Leonidas G. Karagounis, Bjørk W. Helge, William Hagemann, Michael Kjaer, Jerome N. Feige, Pascal Stuelsatz, Abigail L. Mackey   +14 more
wiley   +1 more source

Safeguarding vitality and cognition: The role of sarcopenia in intrinsic capacity decline among octogenarians from multiple cohorts

The Journal of Nutrition, Health and Aging
Background: Sarcopenia and intrinsic capacity (IC) declines pose significant challenges to healthy aging, particularly in the rapidly growing octogenarian population.
Pi-Shan Hsu, Wei-Ju Lee, Li-Ning Peng, Wan-Hsuan Lu, Lin-Chieh Meng, Fei-Yuan Hsiao, Liang-Kung Chen   +6 more
doaj   +1 more source

Relative sarcopenia and mortality and the modifying effects of chronic kidney disease and adiposity

Journal of Cachexia, Sarcopenia and Muscle, 2019
Background Conventional definitions of sarcopenia based on lean mass may fail to capture low lean mass relative to higher fat mass, that is, relative sarcopenia.
Susan L. Ziolkowski, Jin Long, Joshua F. Baker, Glenn M. Chertow, Mary B. Leonard   +4 more
doaj   +1 more source